H1152 promotes the degradation of polyglutamine-expanded ataxin-3 or ataxin-7 independently of its ROCK-inhibiting effect and ameliorates mutant ataxin-3-induced neurodegeneration in the SCA3 transgenic mouse
Keywords: Polyglutamine-expanded ataxin-3; Polyglutamine-expanded ataxin-7; H1152; Rho-kinase inhibitor; SCA3 transgenic mice; Pontine nuclei; SCA3; Spinocerebellar ataxia type 3; ROCK; Rho-kinase; SCA7; Spinocerebellar ataxia type 7;