Keywords: پیش فرآیند; high-concentration protein formulations; formulation development; preformulation; screening tools; prediction; stability; solubility; viscosity;
مقالات ISI پیش فرآیند (ترجمه نشده)
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Keywords: پیش فرآیند; BS; bile salt; Buf; buffer capacity; FaSSIF; fasted state simulated intestinal fluid; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; MES; 2-(N-morpholino)ethanesulfonic acid; Osm; osmolarity; PL; phospholipid; RSD; relative standard deviation;
Keywords: پیش فرآیند; amorphous; solid dispersion; QSPR; structure property relationship; in silico modeling; calorimetry (DSC); microscopy; X-ray powder diffractometry; preformulation; API; active pharmaceutical ingredient; ASD; amorphous solid dispersion; DSC; differential s
Keywords: پیش فرآیند; solvate; crystallography; preformulation; crystallization; desolvation; physical characterization;
Keywords: پیش فرآیند; ACN; acetonitrile; API; active pharmaceutical ingredient; ASD; amorphous solid dispersion; BCS; biopharmaceutical classification system; CAP; cellulose acetate phthalate; DCM; dichloromethane; DMF; N,N-dimethylformamide; DL; drug load; DSC; differential s
Keywords: پیش فرآیند; IBS; NK receptor; Preformulation; Salt screen; Solid-state; Stability;
Keywords: پیش فرآیند; crystallinity; crystallization; drug-like properties; nonlinear regression; physical characterization; physicochemical properties; physicochemical; preformulation; structure-property relationship (SPR);
Keywords: پیش فرآیند; Preformulation; Minoxidil; Effervescent formulations; Hair follicles; Skin permeation;
Keywords: پیش فرآیند; cocrystals; physicochemical properties; preformulation; formulation; crystal engineering; clinical trials;
Keywords: پیش فرآیند; high-throughput technologies; monoclonal antibody; pH; physical stability; preformulation; protein aggregation; protein formulation; fluorescence spectroscopy; biopharmaceuticals characterization; protein folding/refolding;
Keywords: پیش فرآیند; Dual antiplatelet therapy; Interaction/degradation products; Physico-chemical characterization; Polypill; Preformulation; Ticagrelor; Solid-state;
Keywords: پیش فرآیند; Cystinosis; Ophthalmic delivery; Gel; Cysteamine; Preformulation;
Keywords: پیش فرآیند; supersaturation; preformulation; precipitation; oral drug delivery; gastrointestinal; excipients; SDDS; supersaturating drug delivery systems; DS; degree of supersaturation; tind; induction time; DMSO; dimethylsulfoxide; FaSSIF; fasted-state simulated int
Keywords: پیش فرآیند; dissolution; intrinsic dissolution rate; apparent solubility; preformulation; poorly water-soluble drug; small scale;
Keywords: پیش فرآیند; protein formulation; preformulation; protein aggregation; physical stability; light scattering (static); protein; interaction;
Keywords: پیش فرآیند; analytical chemistry; excipients; formulation; imaging methods; particle size; preformulation; Raman spectroscopy; solid dosage form; solid state; tableting;
Keywords: پیش فرآیند; physical stability; particle size; biotechnology; cancer; preformulation; formulation; phase diagram; viral vectors;
Keywords: پیش فرآیند; cocrystals; food effects; oral absorption; supersaturation; physicochemical properties; preformulation; solubility; surfactants; mathematical model; poorly water-soluble drugs;
Keywords: پیش فرآیند; transdermal; transdermal drug delivery; stability; solid state stability; preformulation; physical stability; photodegradation; photochemistry; oxidation; drug–excipient interaction
Keywords: پیش فرآیند; Preformulation; Solid-state; Drug development; Formulation; Drug delivery; Process analytical technologies; Quality control; Dissolution testing;
Keywords: پیش فرآیند; Nanostructured lipid carriers; Ibuprofen; Factorial design; Preformulation; Particle size; Zeta potential;
Keywords: پیش فرآیند; Benznidazole; Chagas disease; Cyclodextrin; Compatibility; Itraconazole; Preformulation
Keywords: پیش فرآیند; Brij 96; Calorimetry (DSC); Preformulation; Nile red; rifampicin; isoniazid; pyrazinamide; Fluorescence spectroscopy; Microemulsions; UV/Vis Spectroscopy;
Keywords: پیش فرآیند; preformulation; excipients; dissolution; stability; salts; hydrate; phase transition; pH; compression; co-crystal;
Keywords: پیش فرآیند; chemical stability; oxidation; HPLC; preformulation; peroxy radical; forced degradation;
Keywords: پیش فرآیند; personalized medicine; preformulation; inkjet printing; flexography; SEM-EDX; physical characterization; poorly water-soluble drugs; oral drug delivery; formulation; microscopy;
Keywords: پیش فرآیند; 9-nitrocamptothecin; physicochemical properties; preformulation; solubility; micelles; hydrolysis; kinetics; N-oxide; pluronic; stability;
Unusual Self-Assembly of the Recombinant Chlamydia trachomatis Major Outer Membrane Protein-Based Fusion Antigen CTH522 Into Protein Nanoparticles
Keywords: پیش فرآیند; vaccines; vaccine delivery; protein formulation; protein structure; protein folding/refolding; protein aggregation; preformulation; mass spectrometry; self-assembly;
Pressure-temperature phase diagram of the dimorphism of the anti-inflammatory drug nimesulide
Keywords: پیش فرآیند; Polymorphism; Thermodynamics; Pressure-temperature phase diagram; Phase behavior; Crystallography; Calorimetry; Preformulation;
Preformulation Characterization, Stabilization, and Formulation Design for the Acrylodan-Labeled Glucose-Binding Protein SM4-AC
Keywords: پیش فرآیند; preformulation; physicochemical characterization; excipients; stabilization; high-throughput fluorescence assay; acrylodan fluorescence; glucose binding; AC; acrylodan; CD; circular dichroism; cIEF; capillary isoelectric focusing; FL; fluorescence; Qr; gl
Visualization of Protonation/Deprotonation of Active Pharmaceutical Ingredient in Solid State by Vapor Phase Amine-Selective Alkyne Tagging and Raman Imaging
Keywords: پیش فرآیند; Raman spectroscopy; solid state; solid dosage form; salts/salt selection; preformulation; physicochemical properties; image analysis; imaging methods; formulation; analytical chemistry;
Supersaturation of zafirlukast in fasted and fed state intestinal media with and without precipitation inhibitors
Keywords: پیش فرآیند; Preformulation; Food effects; Precipitation inhibitors; Amorphous; Biorelevant media; Bioavailability;
Dehydration and Stabilization of a Reactive Tertiary Hydroxyl Group in Solid Oral Dosage Forms of BMS-779788
Keywords: پیش فرآیند; stability; chemical stability; kinetics; pH; preformulation; stabilization; solid dosage form;
Stability hierarchy between Piracetam forms I, II, and III from experimental pressure-temperature diagrams and topological inferences
Keywords: پیش فرآیند; Crystal polymorphism; Solid state; Phase diagram; Phase transition; Physical stability; Preformulation;
Preformulation study and influence of DMSO and propylene glycol on the antioxidant action of isocoumarin paepalantine isolated from Paepalanthus bromelioides
Keywords: پیش فرآیند; Antioxidant; Paepalantine; Preformulation
Characterization and Thermodynamic Relationship of Three Polymorphs of a Xanthine Oxidase Inhibitor, Febuxostat
Keywords: پیش فرآیند; polymorphism; physicochemical properties; calorimetry (DSC); physical characterization; phase transition; physical stability; polymorph; thermal analysis; thermodynamics; preformulation;
Coencapsulation of Hydrophobic and Hydrophilic Antituberculosis Drugs in Synergistic Brij 96 Microemulsions: A Biophysical Characterization
Keywords: پیش فرآیند; nonionic microemulsions; anti-TB drugs; stability; in vitro release; Brij 96; derivative absorbance spectroscopy; UV-visible spectroscopy; solubility; toxicity; preformulation;
Investigation of the Sedimentation Behavior of Aluminum Phosphate: Influence of pH, Ionic Strength, and Model Antigens
Keywords: پیش فرآیند; vaccine adjuvants; Alum; suspension; stabilization; sedimentation analysis; sedimentation volume ratio; preformulation; formulation; physical characterization;
An Intravaginal Ring for the Simultaneous Delivery of an HIV-1 Maturation Inhibitor and Reverse-Transcriptase Inhibitor for Prophylaxis of HIV Transmission
Keywords: پیش فرآیند; polymeric drug delivery system; stability; epithelial delivery/permeability; HIV/AIDS; mucosal drug delivery; extrusion; biocompatibility; physicochemical properties; preformulation; controlled release;
Nebulization of Active Pharmaceutical Ingredients with the eFlow®rapid: Impact of Formulation Variables on Aerodynamic Characteristics
Keywords: پیش فرآیند; active pharmaceutical ingredient; aerosols; aerosol manipulation; excipients; lung deposition; mass median aerodynamic diameter; particle size; preformulation; pulmonary drug delivery; vibrating-mesh nebulizer;
The use of the SeDeM diagram expert system for the formulation of Captopril SR matrix tablets by direct compression
Keywords: پیش فرآیند; SeDeM; Diagram expert system; Preformulation; Direct compression; Quality by Design (ICH Q8); Index good compression (IGC); Captopril; Slow release
A New Apparatus for RealâTime Assessment of the Particle Size Distribution of Disintegrating Tablets
Keywords: پیش فرآیند; excipients; kinetics; tableting; preformulation; particle size; tablet disintegration; superdisintegrants;
In Vivo and Ex Vivo Evaluation of a Multi-Particulate Composite Construct for Sustained Transbuccal Delivery of Carbamazepine
Keywords: پیش فرآیند; carbamazepine; preclinical; controlled release; porous-structured; transbuccal; preformulation; in vitro/in vivo correlation; mathematical model; polymeric drug delivery system; permeation enhancer;
A high throughput platform for understanding the influence of excipients on physical and chemical stability
Keywords: پیش فرآیند; Preformulation; High-throughput screening; Processing; Phase transformation; Excipient
Development of a Stable Virus-Like Particle Vaccine Formulation against Chikungunya Virus and Investigation of the Effects of Polyanions
Keywords: پیش فرآیند; stabilization; thermal analysis; vaccines; particle size; physical stability; physicochemical properties; preformulation; spectroscopy; protein formulation;
Preformulation and Development of a Once-Daily Sustained-Release Tenofovir Vaginal Tablet Tablet Containing A Single Excipient
Keywords: پیش فرآیند; tenofovir; HIV/AIDS; antiretroviral; vaginal tablet; microbicide; hardness; particle size; preformulation; powder technology;
Development of a Codrug Approach for Sustained Drug Delivery Across Microneedle-Treated Skin
Keywords: پیش فرآیند; microneedle; naltrexone; cyclooxygenase inhibitor; codrug; pore closure; permeability; preformulation; stability; metabolism; transdermal;
Long chain lipid based tamoxifen NLC. Part I: Preformulation studies, formulation development and physicochemical characterization
Keywords: پیش فرآیند; Tamoxifen; Preformulation; Solubility; Nanostructured lipid carrier; Stability
Implications of In-Use Photostability: Proposed Guidance for Photostability Testing and Labeling to Support the Administration of Photosensitive Pharmaceutical Products, Part 1: Drug Products Administered by Injection
Keywords: پیش فرآیند; stability; preformulation; photodegradation; photochemistry; injectables; chemical stability; physical stability;
Aluminum Adjuvant Dose Guidelines in Vaccine Formulation for Preclinical Evaluations
Keywords: پیش فرآیند; preformulation; vaccines; vaccine adjuvants; injectables; protein formulation;