دانلود مقالات ISI درباره فن آوری تحلیلی فرآیند (PAT) + ترجمه فارسی

On-line near infrared spectroscopy as a Process Analytical Technology (PAT) tool to control an industrial seeded API crystallization

Keywords: فن آوری تحلیلی فرآیند (PAT); Process Analytical Technology (PAT); Near infrared spectroscopy; On-line measurement; Active pharmaceutical ingredient (API) crystallization;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Lyophilization Process Design Space

Keywords: فن آوری تحلیلی فرآیند (PAT); freeze-drying/lyophilization; quality by design (QbD); process analytical technology (PAT); Design Space; processing; Scale-Up; heat and mass transfer; process validation; primary drying;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Rapid classification of pharmaceutical ingredients with Raman spectroscopy using compressive detection strategy with PLS-DA multivariate filters

Keywords: فن آوری تحلیلی فرآیند (PAT); Compressive detection; Raman spectroscopy; Rapid classification; PLS-DA; Process analytical technology (PAT); Cialis®

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

A novel approach to monitor coating amount by short-wavelength near-infrared spectroscopy using a tracer with a long-chain hydrocarbyl group

Keywords: فن آوری تحلیلی فرآیند (PAT); Process Analytical Technology (PAT); Near-infrared (NIR); In-process monitoring; Film coating; Short wavelength near-infrared (SW-NIR); Long-chain hydrocarbyl

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Wireless transmission of ultrasonic waveforms for monitoring drug tablet properties and defects

Keywords: فن آوری تحلیلی فرآیند (PAT); Wireless transmitter; Drug tablets; Real-time quality monitoring systems; In-die online monitoring; Process analytical technology (PAT)

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Utilizing Dynamic Light Scattering as a Process Analytical Technology for Protein Folding and Aggregation Monitoring in Vaccine Manufacturing

Keywords: فن آوری تحلیلی فرآیند (PAT); protein folding/refolding; protein aggregation; process analytical technology (PAT); biopharmaceuticals characterization; vaccines; light scattering (dynamic); particle sizing;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Development of a methodology to estimate error in the on-line measurements of blend uniformity in a continuous powder mixing process

Keywords: فن آوری تحلیلی فرآیند (PAT); Process Analytical Technology (PAT); Continuous powder mixing; NIR (Near Infra-Red) spectroscopy

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Inline monitoring and a PAT strategy for pharmaceutical hot melt extrusion

Keywords: فن آوری تحلیلی فرآیند (PAT); Hot melt extrusion; Process Analytical Technology (PAT); Near-infrared spectroscopy (NIRS); API content; Quality control

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Improved C-control of crystallization with reduced calibration effort via conductometry

Keywords: فن آوری تحلیلی فرآیند (PAT); Crystallization; Process analytical technology (PAT); Conductivity; Supersaturation control; Crystal size distribution (CSD); Quality-by-design (QbD)

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Process analytical tools for monitoring, understanding, and control of pharmaceutical fluidized bed granulation: A review

Keywords: فن آوری تحلیلی فرآیند (PAT); Fluidized bed granulation; Process Analytical Technology (PAT); In-process monitoring; Control; Process understanding

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2013 سفارش ترجمه

Strategic funding priorities in the pharmaceutical sciences allied to Quality by Design (QbD) and Process Analytical Technology (PAT)

Keywords: فن آوری تحلیلی فرآیند (PAT); Quality by Design (QbD); Process Analytical Technology (PAT); Product design; Personalized healthcare; Continuous processing; Biopharmaceuticals;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2012 سفارش ترجمه

In-line NIR spectroscopy for the understanding of polymer–drug interaction during pharmaceutical hot-melt extrusion

Keywords: فن آوری تحلیلی فرآیند (PAT); NIR spectroscopy; Hot-melt extrusion (HME); Process Analytical Technology (PAT); In-line monitoring; Continuous production

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Acoustic chemometric prediction of total solids in bioslurry: A full-scale feasibility study for on-line biogas process monitoring

Keywords: فن آوری تحلیلی فرآیند (PAT); Acoustic chemometrics; Partial Least Squares Regression (PLS-R); Total Solids (TS); Bioslurry; On-line monitoring; Process Analytical Technology (PAT)

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

THz spectroscopy: An emerging technology for pharmaceutical development and pharmaceutical Process Analytical Technology (PAT) applications

Keywords: فن آوری تحلیلی فرآیند (PAT); Terahertz spectroscopy; Pharmaceutical development; Process Analytical Technology (PAT); Chemometrics; Pharmaceutical manufacturing process; First principles modeling

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

A novel in-line NIR spectroscopy application for the monitoring of tablet film coating in an industrial scale process

Keywords: فن آوری تحلیلی فرآیند (PAT); Process Analytical Technology (PAT); Film coating; Near-Infrared Spectroscopy (NIRS); In-line monitoring; NIR Chemical Imaging (NIR-CI); Multivariate Data Analysis (MVDA);

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Raman spectroscopy for the in-line polymer–drug quantification and solid state characterization during a pharmaceutical hot-melt extrusion process

Keywords: فن آوری تحلیلی فرآیند (PAT); Raman spectroscopy; Hot-melt extrusion (HME); Process Analytical Technology (PAT); In-line measurements; Solid dispersions; Solid solutions

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Real-time predictions of drug release and end point detection of a coating operation by in-line near infrared measurements

Keywords: فن آوری تحلیلی فرآیند (PAT); Coating operation; Dissolution testing; Sustained release tablets; Process analytical technology (PAT); End point determination; Near infrared spectroscopy (NIRS);

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Development of a Process Analytical Technology (PAT) for in-line monitoring of film thickness and mass of coating materials during a pan coating operation

Keywords: فن آوری تحلیلی فرآیند (PAT); Process Analytical Technology (PAT); Near Infrared Spectroscopy (NIRS); In-line measurements; Real-time monitoring; Coating; Terahertz Pulsed Imaging (TPI)

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Real-time in-die compaction monitoring of dry-coated tablets

Keywords: فن آوری تحلیلی فرآیند (PAT); Dry-coated tablets; Real-time quality monitoring systems; In-die online monitoring; Core eccentricity; Process Analytical Technology (PAT)

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Real-time on-line flow cytometry for bioprocess monitoring

Keywords: فن آوری تحلیلی فرآیند (PAT); Process analytical technology (PAT); Bioprocess monitoring; eGFP; Flow-injection; Flow cytometry

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Development, validation and transfer of a Near Infrared method to determine in-line the end point of a fluidised drying process for commercial production batches of an approved oral solid dose pharmaceutical product

Keywords: فن آوری تحلیلی فرآیند (PAT); Process Analytical Technology (PAT); Method validation; Loss on drying in-line monitoring; Near Infrared (NIR); Partial Least Square (PLS)

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Monitoring lentiviral vector production kinetics using online permittivity measurements

Keywords: فن آوری تحلیلی فرآیند (PAT); Lentiviral vector production; HEK293; Perfusion culture; Online monitoring; Permittivity measurements; Dielectric spectroscopy; Process Analytical Technology (PAT)

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Comparison of near infrared and microwave resonance sensors for at-line moisture determination in powders and tablets

Keywords: فن آوری تحلیلی فرآیند (PAT); Near infrared (NIR); Microwave resonance technology (MRT); Process analytical technology (PAT); At-line water determination; Powders; Tablets

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Optimization of a high shear wet granulation process using focused beam reflectance measurement and particle vision microscope technologies

Keywords: فن آوری تحلیلی فرآیند (PAT); process analytical technology (PAT); particle size; granulation; particle technology; physical characterization; processing; online monitoring; process control; FBRM®; quality by design (QBD);

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Quality-by-Design (QbD): An integrated process analytical technology (PAT) approach for a dynamic pharmaceutical co-precipitation process characterization and process design space development

Keywords: فن آوری تحلیلی فرآیند (PAT); Quality-by-Design (QbD); Process analytical technology (PAT); Co-precipitation; Real-time process monitoring; Critical process variable; Design space

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2011 سفارش ترجمه

Development and characterization of “push–pull” sampling device with fast reaction quenching coupled to high-performance liquid chromatography for pharmaceutical process analytical technologies

Keywords: فن آوری تحلیلی فرآیند (PAT); High-performance liquid chromatography (HPLC); Online sampling; Sample preparation; Automation; Process analytical technology (PAT)

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Different modes of dynamic image analysis in monitoring of pharmaceutical dry milling process

Keywords: فن آوری تحلیلی فرآیند (PAT); Process analytical technology (PAT); Conical mill; Process analyzers; Dynamic image analysis; Shape factor; Quality by design

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Mechanical and geometric property characterization of dry-coated tablets with contact ultrasonic techniques

Keywords: فن آوری تحلیلی فرآیند (PAT); Dry-coated tablets; Core eccentricity; Real-time compaction monitoring; Mechanical properties; Acoustic monitoring techniques; Process Analytical Technology (PAT)

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

A PAT Approach to Improve Process Understanding of High Shear Wet Granulation Through In-Line Particle Measurement Using FBRM C35

Keywords: فن آوری تحلیلی فرآیند (PAT); FBRM C35; focused beam reflectance measurement (FBRM); high shear wet granulation; particle size; particle size distribution (PSD); design of experiments (DOE); critical process parameter (CPP); critical quality attribute (CQA); quality by design (QbD); p

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2010 سفارش ترجمه

Evaluation of in-line spatial filter velocimetry as PAT monitoring tool for particle growth during fluid bed granulation

Keywords: فن آوری تحلیلی فرآیند (PAT); Spatial filter velocimetry (SFV); Process analytical technology (PAT); Fluid bed granulation; Particle size (distribution); Process understanding; In-line measurements

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

PAT method to gather bioprocess parameters in real-time using simple input variables and first principle relationships

Keywords: فن آوری تحلیلی فرآیند (PAT); Bioprocessing; Mathematical modeling; Metabolism; Parameter identification; Process Analytical Technology (PAT); Quality by Design (QbD)

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2010 سفارش ترجمه

Quality‐by‐Design (QbD): An Integrated Process Analytical Technology (PAT) Approach for Real‐Time Monitoring and Mapping the State of a Pharmaceutical Coprecipitation Process

Keywords: فن آوری تحلیلی فرآیند (PAT); Quality‐by‐Design (QbD); process analytical technology (PAT); coprecipitation; real‐time process monitoring; incubation; nucleation; crystal growth; crystal size distribution (CSD); principal component analysis; process trajectory;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2010 سفارش ترجمه

NIR techniques create added values for the pellet and biofuel industry

Keywords: فن آوری تحلیلی فرآیند (PAT); Near infrared spectroscopy; Bi-orthogonal partial least squares (BPLS); Multivariate calibration; Multivariate statistical process control; Process analytical technology (PAT)

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Quality-by-Design (QbD): An integrated multivariate approach for the component quantification in powder blends

Keywords: فن آوری تحلیلی فرآیند (PAT); Quality-by-Design (QbD); Process analytical technology (PAT); Design of experiments; Multivariate statistical data analysis; Powder blending; Component quantification; Moving block standard deviation; ANOVA; Scale of scrutiny; Modeling

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Quality-By-Design (QbD): An Integrated Approach for Evaluation of Powder Blending Process Kinetics and Determination of Powder Blending End-point

Keywords: فن آوری تحلیلی فرآیند (PAT); quality-by-design (QbD); process analytical technology (PAT); design of experiments; multivariate statistical data analysis; powder blending; process monitoring; blending end-point determination; moving block standard deviation; process dynamics;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2009 سفارش ترجمه

In-line and real-time process monitoring of a freeze drying process using Raman and NIR spectroscopy as complementary process analytical technology (PAT) tools

Keywords: فن آوری تحلیلی فرآیند (PAT); process analytical technology (PAT); Raman spectroscopy; NIR spectroscopy; freeze drying; process monitoring; principal component analysis (PCA); multivariate curve resolution (MCR)

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2009 سفارش ترجمه

In-vitro tomography and non-destructive imaging at depth of pharmaceutical solid dosage forms

Keywords: فن آوری تحلیلی فرآیند (PAT); Solid dosage form; Tomography; Non-destructive testing; Process analytical technology (PAT); Controlled release; X-ray microtomography; Magnetic resonance imaging (MRI); NMR imaging; NMR microscopy; Terahertz pulsed imaging (TPI); Optical coherence tomogr

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2009 سفارش ترجمه

Direct determination of ephedrine intermediate in a biotransformation reaction using infrared spectroscopy and PLS

Keywords: فن آوری تحلیلی فرآیند (PAT); Biocatalysis; Reaction monitoring; Process analytical technology (PAT); Infrared spectroscopy

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Controlling granule size by granulation liquid feed pulsing

Keywords: فن آوری تحلیلی فرآیند (PAT); Fluid-bed granulation; Particle-size distribution; Granule growth; Process analytical technology (PAT)

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Near-infrared reflectance spectroscopy as a process analytical technology tool in Ginkgo biloba extract qualification

Keywords: فن آوری تحلیلی فرآیند (PAT); Near-infrared spectroscopy; Qualification; Ginkgo biloba; Pharmaceutical products; Process analytical technology (PAT)

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Delayed Release Tablet Dissolution Related to Coating Thickness by Terahertz Pulsed Image Mapping

Keywords: فن آوری تحلیلی فرآیند (PAT); Asacol; mesalamine; mesalazine; delayed release; terahertz pulsed imaging; coating mapping; mean dissolution time (MDT); process analytical technology (PAT);

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Perspectives in the use of spectroscopy to characterise pharmaceutical solids

Keywords: فن آوری تحلیلی فرآیند (PAT); Amorphous forms; Computational chemistry; Multivariate analysis; Polymorphism; Processing-induced transformation (PIT); Process analytical technology (PAT); Solid state; Spectroscopic methods

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2008 سفارش ترجمه

Process Analytical Technology (PAT): Quantification Approaches in Terahertz Spectroscopy for Pharmaceutical Application*

Keywords: فن آوری تحلیلی فرآیند (PAT); process analytical technology (PAT); terahertz spectroscopy; chemometrics; multivariate analysis; spectral superposition; univariate method; partial least squares; spectral preprocessing algorithms; excipients; interaction;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2008 سفارش ترجمه

Noncontact Photo-Acoustic Defect Detection in Drug Tablets

Keywords: فن آوری تحلیلی فرآیند (PAT); drug tablet monitoring; noncontact process monitoring; process monitoring; defective drug tablets; Process Analytical Technology (PAT);

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Analysis of sustained-release tablet film coats using terahertz pulsed imaging

Keywords: فن آوری تحلیلی فرآیند (PAT); Terahertz pulsed imaging; Film coating; Refractive index; Coating uniformity; Process analytical technology (PAT)

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

Analysis of Coating Structures and Interfaces in Solid Oral Dosage Forms by Three Dimensional Terahertz Pulsed Imaging

Keywords: فن آوری تحلیلی فرآیند (PAT); terahertz pulsed imaging; far infrared; structural imaging; coating analysis; film coating; sugar coating; tablets; multilayer tablet; soft gelatin capsules; process analytical technology (PAT);

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Process analytical technology (PAT): Effects of instrumental and compositional variables on terahertz spectral data quality to characterize pharmaceutical materials and tablets

Keywords: فن آوری تحلیلی فرآیند (PAT); Process analytical technology (PAT); Terahertz spectroscopy; Measurement process; Crystalline materials; Amorphous state; Characterization; Mass-transfer analysis

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

In Situ Raman Spectroscopy for In-Line Control of Pharmaceutical Crystallization and Solids Elaboration Processes: A Review

Keywords: فن آوری تحلیلی فرآیند (PAT); particulate processes; process analytical technology (PAT); crystallization; control; polymorphism

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2007 سفارش ترجمه

Evaluation of tunable diode laser absorption spectroscopy for in‐process water vapor mass flux measurements during freeze drying

Keywords: فن آوری تحلیلی فرآیند (PAT); freeze drying; process analytical technology (PAT); operational qualification (OQ); scale‐up; heat and mass transfer in freeze drying; laser technology;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2007 سفارش ترجمه

A Process Analytical Technology approach to near-infrared process control of pharmaceutical powder blending. Part III: Quantitative near-infrared calibration for prediction of blend homogeneity and characterization of powder mixing kinetics

Keywords: فن آوری تحلیلی فرآیند (PAT); Process Analytical Technology (PAT); near-infrared spectroscopy; mixing; blend uniformity analysis; UV/VIS spectroscopy; multivariate analysis; principal component analysis; principal component regression; partial least squares; multi-term linear regressi

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2006 سفارش ترجمه