The Polybasic N-Terminal Region of the Prion Protein Controls the Physical Properties of Both the Cellular and Fibrillar Forms of PrP
Keywords: PrP, prion protein; PrPC, cellular isoform of the prion protein; PrPSc, disease-associated isoform of the prion protein; PrP 23–231, full-length recombinant prion protein; PrP 31–231, recombinant prion protein encompassing residues 31–231; α-PrP, alpha-he