Stereo-specific synthesis of analogs of nerve agents and their utilization for selection and characterization of paraoxonase (PON1) catalytic scavengers
Keywords: OPH, organophosphate hydrolase; PTE, phosphotriesterase; PON, paraoxonases; CHMC, 3-cyano-7-hydroxy-4-methylcoumarin; hAChE, recombinant human AChE; TcAChE, Torpedo californica AChE; EMP, O-ethyl methylphosphonyl; nPrMP, O-n-propyl methylphosphonyl; iPrMP