Keywords: PTEN، فسفاتاز و تنسین همولوگ; CAT, catalase; FAK, focal adhesion kinase; H2O2, hydrogen peroxide; MMP, matrix metalloproteinase; Nox, NADPH oxidase; p130cas, Crk-associated substrate; PIP3, phosphatidylinositol (3,4,5)-trisphosphate; PTEN, phosphatase and tensin homolog; PTP, protein
مقالات ISI PTEN، فسفاتاز و تنسین همولوگ (ترجمه نشده)
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Keywords: PTEN، فسفاتاز و تنسین همولوگ; ROCK, Rho-associated protein kinase; Akt, protein kinase B; PTEN, phosphatase and tensin homolog; GSK3β, glycogen synthase kinase 3β; CUMS, chronic unpredictable mild stress; CMC-Na, carboxymethyl cellulose; IL-1β, interleukin 1β; IL-6, interleukin 6; TNF
Frequency of PTEN alterations, TMPRSS2-ERG fusion and their association in prostate cancer
Keywords: PTEN، فسفاتاز و تنسین همولوگ; PTEN, phosphatase and tensin homolog; TMPRSS2, trans membrane protease, serine 2; ERG, erythroblastosis virus E26 oncogene homolog; PCA, prostate cancer; FISH, fluorescent in situ hybridization; PSA, prostate-specific antigenPTEN; TMPRSS2-ERG; Prostate ca
First application of the Automated QUantitative Analysis (AQUA) technique to quantify PTEN protein expression in ovarian cancer: A correlative study of NCIC CTG OV.16
Keywords: PTEN، فسفاتاز و تنسین همولوگ; OC, epithelial ovarian cancer; PTEN, phosphatase and tensin homolog; AQUA, Automated QUantitative Analysis; RD, residual disease; OS, overall survival; PFS, progression free survival; RR, response rate; HR, hazard ratioBRCA1; PTEN; Ovarian carcinoma; AQUA
Discovery and antiplatelet activity of a selective PI3Kβ inhibitor (MIPS-9922)
Keywords: PTEN، فسفاتاز و تنسین همولوگ; PI3 kinase; Kinase selectivity; Platelet aggregation inhibitors; ThrombosisACD, Acid citrate dextrose; PTEN, phosphatase and tensin homolog; ADME, absorption, distribution, metabolism, and excretion; TRAP, thrombin receptor activating peptide; PRP, platel
NMDA receptor activation regulates sociability by its effect on mTOR signaling activity
Keywords: PTEN، فسفاتاز و تنسین همولوگ; TSC, Tuberous Sclerosis Complex; ASD, Autism spectrum disorder; mTORC1, Mammalian target of rapamycin complex 1; Rheb, Ras homolog enriched in brain; mTOR, Mammalian target of rapamycin; PTEN, Phosphatase and tensin homolog; NMDA, N-methyl-D-aspartate; ER
Investigating the effects of in utero benzene exposure on epigenetic modifications in maternal and fetal CD-1 mice
Keywords: PTEN، فسفاتاز و تنسین همولوگ; γH2AX, phosphorylated histone H2A variant X; TSA, trichostatin A; Parp-1, poly[ADP-ribose] synthase 1; HAT, histone acetyltransferase; Pten, phosphatase and tensin homolog; MAGE1, melanoma antigen 1; HDAC, histone deacetylase; DNMT, DNA methyl transferase
MiR-429 increases the metastatic capability of HCC via regulating classic Wnt pathway rather than epithelial–mesenchymal transition
Keywords: PTEN، فسفاتاز و تنسین همولوگ; HCC, hepatocellular carcinoma; PVTT, portal vein tumor thrombus; PT, HCC primary tumor; NT, peri-cancerous tissues; H&E, hematoxylin and eosin; miR-429, microRNA-429; PTEN, phosphatase and tensin homolog; MMP2, matrix metallopeptidase 2; MMP7, matrix meta
miR-29b suppresses proliferation, migration, and invasion of tongue squamous cell carcinoma through PTEN–AKT signaling pathway by targeting Sp1
Keywords: PTEN، فسفاتاز و تنسین همولوگ; TSCC, tongue squamous cell carcinoma; Sp1, specificity protein 1; 3′ UTR, 3′ untranslated region; miRNAs, MicroRNAs; PTEN, phosphatase and tensin homolog; PI3K, phosphatidylinositol-3-kinase; DNMT3A/3B, DNA methyltransferase 3A/3B; HOK, human oral keratin
Long non-coding RNA ANRIL (CDKN2B-AS) is induced by the ATM-E2F1 signaling pathway
Keywords: PTEN، فسفاتاز و تنسین همولوگ; DDR, DNA damage response; hnRNP-K, heterogeneous nuclear ribonucleoprotein K; PTEN, phosphatase and tensin homolog; PTENP1, PTEN pseudogene 1; PI3K, phosphatidylinositide 3-kinases; CTNNB1, cadherin-associated protein β1; INK4, inhibitors of CDK4Long non-
miRNAs, a potential target in the treatment of Non-Small-Cell Lung Carcinomas
Keywords: PTEN، فسفاتاز و تنسین همولوگ; NSCLC, Non Small Cell Lung Cancer; HEF1, Human Enhancer of Filamentation 1; EGF receptors, Epidermal Growth Factor receptors; vEGF, vascular Endothelial Growth Factor; PTEN, Phosphatase and TENsin Homolog; BCL-2, B-Cell Lymphoma 2; PCR, Polymerisation Cha
PIWIL4 regulates cervical cancer cell line growth and is involved in down-regulating the expression of p14ARF and p53
Keywords: PTEN، فسفاتاز و تنسین همولوگ; PIWIL4, Piwi-like protein 4; PTEN, phosphatase and tensin homolog; PBS, phosphate buffered saline; MTT, 3-(4,5)-dimethylthiahiazo(-z-y1)-3,5-di-phenytetrazoliumromide; TUNEL, terminal deoxynucleotidyl transferase dUTP nick end labeling; PCR, polymerase ch
Thymoquinone: Potential cure for inflammatory disorders and cancer
Keywords: PTEN، فسفاتاز و تنسین همولوگ; PTEN, phosphatase and tensin homolog; STAT3, signal transducer and activator of transcription 3; PPAR-γ, peroxisome proliferator-activated receptors gamma; ROS, reactive oxygen species; NO, nitric oxide; TNF-α, tumor necrosis factor; IL, interleukin; MAPK
Endocrine-active chemicals in mammary cancer causation and prevention
Keywords: PTEN، فسفاتاز و تنسین همولوگ; DES, diethylstilbestrol; BPA, bisphenol A; TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin; DMBA, dimethylbenz[a]anthracene; PND, postnatal day; ER, estrogen receptor; PR, progesterone receptor; PTEN, phosphatase and tensin homolog; NMU, N-nitroso-N-methylurea;
Selenoprotein W promotes cell cycle recovery from G2 arrest through the activation of CDC25B
Keywords: PTEN، فسفاتاز و تنسین همولوگ; BIAM, biotin conjugated IAM; DCFH-DA, 2’, 7’–dichlorofluorescein diacetate; DTT, dithiothreitol; GSH, glutathione; IAM, iodoacetamide; IR, irradiation; NAC, N-acetyl cysteine; PTEN, phosphatase and tensin homolog; ROS, reactive oxygen species; s.d., stand
Family friction as ΔNp73 antagonises p73 and p53
Keywords: PTEN، فسفاتاز و تنسین همولوگ; ATM, Ataxia Telangiectasia Mutated; MEF, mouse embryonic fibroblast; Mdm2, double minute protein; PTEN, phosphatase and tensin homolog; p53AIP1, p53 apoptosis inducing protein 1; PIR2, p73 induced RING 2 protein; SAOS, sarcoma osteogenic; WT, wild type; 5
Autophagy in cancer: Having your cake and eating it
Keywords: PTEN، فسفاتاز و تنسین همولوگ; LC3, microtubule-associated protein 1 light chain 3; OIS, oncogene-induced senescence; PI3K, phosphoinositide 3-kinase; mTOR, mammalian target of rapamycin; PTEN, phosphatase and tensin homolog; NRF2, NF-E2-related factor 2; HDF, human diploid fibroblasts
Flaxseed oil–trastuzumab interaction in breast cancer
Keywords: PTEN، فسفاتاز و تنسین همولوگ; ALA, alpha-linolenic acid; BD, basal diet; DHA, docosahexaenoic acid; EPA, eicosapentaenoic acid; FAS, fatty acid synthase; FS, flaxseed; FO, flaxseed oil; HER2, human epidermal growth factor receptor-2; PTEN, phosphatase and tensin homolog; TAM, tamoxife
Nucleophosmin is overexpressed in thyroid tumors
Keywords: PTEN، فسفاتاز و تنسین همولوگ; NPM, nucleophosmin; ARF, alternative reading frame; FA, follicular adenomas; PTC, papillary thyroid carcinoma; FTC, follicular thyroid carcinomas; UC, undifferentiated carcinomas; PTEN, phosphatase and tensin homolog; HA, hemagglutininNucleophosmin; Thyro
MicroRNAs in immune regulation—Opportunities for cancer immunotherapy
Keywords: PTEN، فسفاتاز و تنسین همولوگ; miR, microRNA; DAMP, damage associated molecular pattern; PAMP, pathogen associated molecular pattern; DC1, type-1 dendritic cell; DC2, type-2 dendritic cell; Th1, type-1 T help cell; E2F, E2 transcription factor; PTEN, phosphatase and tensin homolog; IL,
The clinicopathologic values of the molecules associated with the main pathogenesis of the glioblastoma
Keywords: PTEN، فسفاتاز و تنسین همولوگ; IHC, immunohistochemistry; EGFR, epidermal growth factor receptor; pAkt or PKB, protein kinase B; PTEN, phosphatase and tensin homolog; PI3K, phosphoinositide 3-kinase; IHC, immunohistochemistry; FISH, fluorescence in situ hybridizationGlioblastoma; Progn
Inhibitors of phosphatidylinositol-3-kinase in cancer therapy
Keywords: PTEN، فسفاتاز و تنسین همولوگ; PI3K, phosphatidylinositol-3-kinase; mTor, mammalian target of rapamycin; ATM, Ataxia telangiectasia mutated; PTEN, phosphatase and tensin homolog; IGFR, insulin-like growth factor receptor; EGFR, epidermal growth factor receptor; PDK, phosphatidylinosito
Differential regulation of Akt/protein kinase B isoforms during cell cycle progression
Keywords: PTEN، فسفاتاز و تنسین همولوگ; MEF, mouse embryo fibroblast; PI3K, phosphatidylinositol 3-kinase; PtdIns-(3,4,5)P3, phosphatidylinositol 3,4,5-trisphosphate; PTEN, phosphatase and tensin homolog; PKB, protein kinase B; PH, pleckstrin homology; mTOR, mammalian target of rapamycinAkt/pro
Thyroid hormone regulation of stem cell development during intestinal remodeling
Keywords: PTEN، فسفاتاز و تنسین همولوگ; T3, thyroid hormone; TR, thyroid hormone receptor; PTEN, phosphatase and tensin homolog; rER, rough endoplasmic reticulum; RXR, 9-cis retinoic acid receptors; TRE, thyroid hormone response element; SMRT, silencing mediator for retinoid and thyroid recepto
MicroRNA-21 Regulates Expression of the PTEN Tumor Suppressor Gene in Human Hepatocellular Cancer
Keywords: PTEN، فسفاتاز و تنسین همولوگ; FAK, focal adhesion kinase; miRNA, microRNA; MMP, matrix metalloprotease; PCR, polymerase chain reaction; PTEN, phosphatase and tensin homolog; siRNA, small interfering RNA
Models representing type I and type II human endometrial cancers: Ishikawa H and Hec50co cells
Keywords: PTEN، فسفاتاز و تنسین همولوگ; CDK, Cyclin-dependent kinase; EGFR, epidermal growth factor receptor; ERK, extracellular regulated kinase; PBS, phosphate buffered saline; PTEN, phosphatase and tensin homolog; RB, retinoblastoma; RBL, retinoblastoma like; HE, Hematoxylin Eosin; PIP3, pho
Infection of Human Immunodeficiency Virus and Intracellular Viral Tat Protein Exert a Pro-survival Effect in a Human Microglial Cell Line
Keywords: PTEN، فسفاتاز و تنسین همولوگ; HIV-1, human immunodeficiency virus type 1; PTEN, phosphatase and tensin homolog; CNS, central nervous system; HCV, hepatitis type C virus; HTLV-1, human T-cell leukemia virus type 1; PI-3-K, PI-3-kinase; CHX, cycloheximide; GFP, green fluorescent protein
Comparison of replicative senescence and stress-induced premature senescence combining differential display and low-density DNA arrays
Keywords: PTEN، فسفاتاز و تنسین همولوگ; HDFs, human diploid fibroblasts; RS, replicative senescence; SIPS, stress-induced premature senescence; t-BHP, tert-butylhydroperoxide; EtOH, Ethanol; PTEN, phosphatase and tensin homolog; IGFBP-3, insulin-like growth factor binding protein-3; LRP-1, lipo