
Unfolding of the immunoglobulin light and heavy chains is required for the enzymatic removal of N-terminal pyroglutamyl residues
Keywords: PTH، phenylthiohydantoin; PGAP, pyroglutamate aminopeptidase (pyrrolidone carboxyl peptidase); PVDF, polyvinylidene difluoride; DTT, dithiotreitol; PTH, phenylthiohydantoin; Mab, monoclonal antibody; PVP, polyvinyl pyrrolidoneImmunoglobulin; Pyroglutamate aminopeptidase; Unfolding