دانلود مقالات ISI درباره Pybop + ترجمه فارسی

ارتباط ساختار-فعالیت مولفین های پنتاپپتید سیکل به عنوان افزایش دهنده های فیبرینولیز

Structure-activity relationship of cyclic pentapeptide malformins as fibrinolysis enhancers

Keywords: RNCGDQLZIATDOU-ZDRBWGSPSA-N; ICYPJNZJUFGALC-PDTBJYIYSA-N; PDRMAVOIWIVXKH-SFUSBHMVSA-N; ISADXJRTBSLWPX-ZDRBWGSPSA-N; NLBLLPROASDPSC-QWWZWVQMSA-N; XKMIKZDBUOHHDK-ZDRBWGSPSA-N; BTURADNXKHTWGA-IJOLSIAMSA-N; UEKHRDLXBMZMPD-ZYIYBEKCSA-N; UQCLCXDOXVZEOA-JARUQAPT

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

سنتز جامد فیزیکی کتابخانه های مشتقات آمینو استروئید اتینیل شده به عنوان عوامل بالقوه آن لوکمی

Solid-phase synthesis of libraries of ethynylated aminosteroid derivatives as potential antileukemic agents

Keywords: AA; amino acid; AcOH; acetic acid; 6-Cl-HOBt; 6-chloro-1-hydroxybenzotriazole; DCM; dichloromethane; DIPEA; N,N-diisopropylethylamine; DMF; N,N-dimethylformamide; Fmoc; 9-fluorenylmethoxycarbonyl; h; hour; HOBt; 1-hydroxybenzotriazole hydrate; HPLC; high-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

کشف یک بازدارنده استروئیدی سولفاتاز مبتنی بر سولفامات با خواص مولکول گیرنده استروژن انتخابی درونی

Discovery of a sulfamate-based steroid sulfatase inhibitor with intrinsic selective estrogen receptor modulator properties

Keywords: Sulfatase; Enzyme; Inhibitor; Estrogen; Cancer; SERM; ALP; alkaline phosphatase; DEA; diethylamine; DHEA; dehydroepiandrosterone; DHEAS; dehydroepiandrosterone sulfate; 5-diol; 5-androstene-3β,17β-diol; DIPEA; diisopropylamine; E1; estrone; E1S; estrone

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

سنتز جامد فیزیکی مایکروویو از پپتیدهای سیکللی لاکتام پل زنجیره جانبی به زنجیره جانبی

Microwave-assisted solid-phase synthesis of side-chain to side-chain lactam-bridge cyclic peptides

Keywords: Cyclic peptides; Microwave assisted synthesis; Lactam-bridge cyclic peptides; SHU9119; MTII; MWA-SPPS; microwave-assisted solid phase peptide synthesis; MBHA; methylbenzhydryl; MCR; melanocortin receptors; NDP; [Nle4, DPhe7]-αMSH; MTII; melanotan-II; RP-

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Lactam hybrid analogues of solonamide B and autoinducing peptides as potent S. aureus AgrC antagonists

Keywords: Autoinducing peptides; Anti-virulence therapy; Solonamide; Quorum-sensing system; Staphylococcus aureus; AIP; autoinducing peptide; CA-MRSA; community-associated; Dap; (S)-2,3-diaminopropamoic acid; Fmoc; fluoren-9-ylmethoxycarbonyl; hLeu; homoleucine; HO

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2018 سفارش ترجمه

Rationally designed divalent caffeic amides inhibit amyloid-β fibrillization, induce fibril dissociation, and ameliorate cytotoxicity

Keywords: Amyloid-β; Alzheimer's disease; Caffeic acid; Divalent caffeic amide; Inhibitor; Cytotoxicity; Aβ; amyloid-β; AD; Alzheimer's disease; CA; caffeic acid; CCS; collision cross-section; DMF; dimethylformamide; EDCI; 1-ethyl-3-(3-dimethylaminopropyl) carbo

دانلود رایگان متن کامل مقاله ISI 62 صفحه سال انتشار : 2018 سفارش ترجمه

Phenylglycine racemization in Fmoc-based solid-phase peptide synthesis: Stereochemical stability is achieved by choice of reaction conditions

Keywords: COMU; (1-cyano-2-ethoxy-2-oxoethylidenaminooxy)dimethylaminomorpholinocarbenium hexafluorophosphate; DBU; 1,8-diazabicyclo[5.4.0]undec-7-ene; DEPBT; 3-diethoxyphosphoryloxy)-1,2,3-benzotriazin-4(3H)-one; DIPEA; N,N-diisopropylethylamine; DMF; N,N-dimethyl

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2017 سفارش ترجمه

First example of peptides targeting the dimer interface of Leishmania infantum trypanothione reductase with potent in vitro antileishmanial activity#

Keywords: Peptides; Helix stabilization; Protein-protein interactions; Trypanothione reductase; Leishmania infantum; Cell-penetrating peptides; CPP; cell-penetrating peptide; DSSP; define secondary structure of proteins algorithm; ELISA; Enzyme-Linked ImmunoSorbent

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

Effect of TLR ligands co-encapsulated with multiepitopic antigen in nanoliposomes targeted to human DCs via Fc receptor for cancer vaccines

Keywords: AAA; amino acid analysis; C18; octadecylsilica; DIEA; N,N-diisopropyl-ethylamine; DIPCDI; N,N'-Diisopropylcarbodiimide; DMF; N,N-dimethylformamide; DMSO; dimethyl sulfoxide Fmoc, 9-fluorenylmethoxycarbonyl; HOAt; 1-hydroxy-7-azabenzotriazole (3-hydroxy-

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

5-Substituted 3-chlorokenpaullone derivatives are potent inhibitors of Trypanosoma brucei bloodstream forms

Keywords: ACN; acetonitrile; CDK; cyclin-dependent kinase; CLK; cdc2-like kinase; CK; casein kinase; DIPEA; diisopropylethylamine; DMEM; Dulbecco's modified Eagle's medium; DMF; N,N-dimethylformamide; DMSO; dimethyl sulfoxide; DYRK1A; dual specificity tyrosine

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Antimicrobial and host cell-directed activities of Gly/Ser-rich peptides from salmonid cathelicidins

Keywords: Antimicrobial peptide; Trout cathelicidin; Antibacterial activity; Immunomodulation; Head kidney leukocytes; AMP; Antimicrobial peptide; BSA; Bovine serum albumin; CD; Circular dichroism; CFU; Colony forming units; DCM; Dichloromethane; DIPEA; Diisopropyl

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Discovery of antitumor anthra[2,3-b]furan-3-carboxamides: Optimization of synthesis and evaluation of antitumor properties

Keywords: Anthra[2,3-b]furan-3-carboxamides; DNA ligands; Topoisomerase inhibitors; Protein kinase inhibitors; Cytotoxicity; Circumvention of multidrug resistance; Antitumor activity; CDI; 1,1′-carbonyldiimidazole; DCC; N,N′-dicyclohexylcarbodiimide; EDC; 1-eth

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

Design, synthesis and biological evaluation of pyrido[2,3-d]pyrimidin-7-(8H)-ones as HCV inhibitors

Keywords: Hepatitis C; HCV genotype 1b replicon; Small molecule inhibitor; Pyrido[2,3-d]pyrimidin-7-(8H)-ones; BOP; (Benzotriazol-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; m-CPBA; 3-Chloroperbenzoic acid; DBU; 1,8-Diazabicyclo[5.4.0]undec-7-ene; D

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2016 سفارش ترجمه

A novel synthetic luteinizing hormone-releasing hormone (LHRH) analogue coupled with modified β-cyclodextrin: Insight into its intramolecular interactions

Keywords: BOP; benzotriazole-1-yl-oxy-tris-(dimethylamino)-phosphonium hexafluorophosphate; CLTR-Cl; 2-chlorotrityl chloride; DCC; N,N′-dicyclohexylcarbodiimide; DMA; dimethylacetamide; DIC; N,N′-diisopropylcarbodiimide; DIEA; diisopropylethylamine; DMF; N,N-di

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

PEGylation of the peptide Bac7(1-35) reduces renal clearance while retaining antibacterial activity and bacterial cell penetration capacity

Keywords: Antimicrobial peptide; Proline-rich; PEGylation; Antibacterial activity; Cell penetrating; Optical imaging; Boc2O; Di-t-butyl dicarbonate; Et2O; ethyl ether; CFU; colony forming unit; Cmc; S-carboxymethyl-cysteine; DIEA; N,N-Diisopropylethylamine; HCTU; 2

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

[Dmt1]DALDA analogues with enhanced μ opioid agonist potency and with a mixed μ/κ opioid activity profile

Keywords: Boc; tert-butyloxycarbonyl; DAMGO; H-Tyr-d-Ala-Gly-Phe(NMe)-Gly-ol; Dmp; 2′,6′-dimethylphenylalanine; Dmt; 2′,6′-dimethyltyrosine; [Dmt1]DALDA; H-Dmt-d-Arg-Phe-Lys-NH2; DSLET; H-Tyr-d-Ser-Gly-Phe-Leu-Thr-OH; EDT; 1,2-ethanediol; Emp; 2′-ethyl-6â

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Linear and cyclic glycopeptide as HIV protease inhibitors

Keywords: HIV-1 protease; Linear and cyclic glycopeptides; Solid and solution peptide synthesis; Molecular docking; AIDS; acquired immunodeficiency syndrome; CTC; 2-chlorotrityl chloride; DCM; dichloromethane; DIPEA; N,N-diisopropyl ethylamine; DMF; N,N-dimethylfor

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2013 سفارش ترجمه

Discovery of novel A3 adenosine receptor ligands based on chromone scaffold

Keywords: [3H]CCPA; [3H](2R,3R,4S,5R)-2-[2-chloro-6-(cyclopentylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol; [3H]HEMADO; [3H] 2-(1-Hexynyl)-N6-methyladenosine; [3H]NECA; [3H]adenosine-5′-(N-ethylcarboxamide); AR; Adenosine receptor; Arg; arginine; Asn; as

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Weight loss effects of quaternary salts of 5-amino-1-(chloromethyl)-1,2-dihydro-3H-benz[e]indoles; structure-activity relationships

Keywords: AIBN; 2,2′-azobis[isobutyronitrile]; CBI; seco-1,2,9,9a-tetrahydrocyclopropa[c]benz[e]indol-4-one; CSA; camphorsulfonic acid; DIPEA; diisopropylethylamine; DMA; dimethylacetamide; DMAP; 4-dimethylaminopyridine; EDCI·HCl; N-ethyl-N′-(3-dimethylaminopr

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2012 سفارش ترجمه

Accelerating lead optimization of chromone carboxamide scaffold throughout microwave-assisted organic synthesis

Keywords: Chromone carboxamide; Microwave-assisted organic synthesis; Lead optimization program; PyBOP; PCl3O;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2011 سفارش ترجمه

Positively charged amino acids flanking a sumoylation consensus tetramer on the 110 kDa tri-snRNP component SART1 enhance sumoylation efficiency

Keywords: Bis-Tris; 2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)propane-1,3-diol; E1; SUMO activating enzyme; E2; SUMO protein carrier protein; E3; SUMO ligase; Fmoc; 9H-fluorenylmethyloxycarbonyl; IPTG; isopropyl-β-D-thiogalactopyranoside; NMM; N-methylmorpholi

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

An efficient route to VEGF-like peptide porphyrin conjugates via microwave-assisted 'click-chemistry'

Keywords: Porphyrins; Angiogenesis; Click-chemistry; Microwaves; PDT; Cyclic peptide; Abs301; absorbance at 301 nm; AcOH; acetic acid; All; allyl; Boc; tert-butoxycarbonyl; Da; dalton; DIEA; N,N-diisopropylethylamine; DMAc; N,N-dimethylacetamide; DMF; N,N-dimethyl

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Synthesis of chiral threefold and sixfold functionalized macrocyclic imidazole peptides

Keywords: Amino acids; Cyclization; Imidazoles; Macrocycles; Peptidomimetics; Bn; benzyl; Boc; tert-butyloxycarbonyl; DCM; dichloromethane; DMF; N,N-dimethylformamide; NMM; N-methylmorpholine; PhtN; phthalimido; PyBOP; benzotriazole-1-yloxytrispyrrolidinophosphoniu

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Modification of guanine residues in PNA-synthesis by PyBOP

Keywords: Coupling reagents; PNA synthesis; Guanine; PyBOP; HATU;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2006 سفارش ترجمه

Solid-phase synthesis of backbone-cyclized β-helical peptides

Keywords: Alkanesulfonamide; Safety-catch linker; Cyclic peptide; Solid-phase peptide synthesis; β-Hairpin; β-Turn; β-Helix; HPLC; Gel-permeation chromatography; AS-SLC; alkanesulfonamide safety-catch linker; CBC; cleavage-by-cyclization; Boc; t-butoxycarbonyl;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Introduction of the Aib-Pro unit into peptides by means of the 'azirine/oxazolone method' on solid phase

Keywords: α-Aminoisobutyric acid; Azirine/oxazolone method; Peptaibols; Peptide synthesis; Photocleavable linker; Aib; α-aminoisobutyric acid; DIPEA; N,N-diisopropylethylamine; HOBt; 1-hydroxybenzotriazole; PyBOP; (1H-benzotriazol-1-yloxy)tripyrrolidinophosphoniu

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Chemical synthesis and NMR characterization of structured polyunsaturated triacylglycerols

Keywords: Polyunsaturated fatty acids; Triacylglycerols; Structured lipids; PyBOP; NMR structural analysis; Positional distribution

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Synthesis and preliminary physical applications of a rhodamin-biotin phosphatidylethanolamine, an easy attainable lipid double probe

Keywords: Boc; tertio-butyloxycarbonyl; DBU; 1,8-diazabicyclo[5,4,0]undec-7-ene; DHB; 2,5-dihydroxybenzoic acid; DIEA; diisopropyl ethyl amine; DMAP; 4-N,N-dimethylaminopyridine; DMF; N,N-dimethylformamide; DSPE; distearyl-phosphatidylethanolamine; Fmoc; 9-fluoreny

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه