Keywords: پیریدازینون; Solid state reaction; Azines; Pyrazoles; Pyridazinones; Solvent-free conditions;
مقالات ISI پیریدازینون (ترجمه نشده)
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A telescoped protocol for the synthesis of new pyrrolo [3,4-d]pyridazinones by cascade reactions
Keywords: پیریدازینون; Vinyl azides; 2H-Azirines; Pyridazinones; Cascade reactions; Pyrrolo[3,4-d]pyridazinones;
Synthesis and evaluation of anticancer activity of some novel 6-aryl-2-(p-sulfamylphenyl)-pyridazin-3(2H)-ones
Keywords: پیریدازینون; Pyridazinones; Benzenesulfonamides; Sulfonamides; Anticancer; Antiproliferative activity
An efficient chemo- and regioselective three-component synthesis of pyridazinones and phthalazinones using activated KSF
Keywords: پیریدازینون; Regioselective; Pyridazinones; Phthalazinones; Montmorillonite-KSF
New pyridazinone derivatives with vasorelaxant and platelet antiaggregatory activities
Keywords: پیریدازینون; Pyridazinones; Butenolides; Vasorelaxant; Antiplatelet agents
Discovery of 5-substituted-N-arylpyridazinones as inhibitors of p38 MAP kinase
Keywords: پیریدازینون; p38; Pyridazinones; Kinase
Synthesis and vasodilatory activity of some amide derivatives of 6-(4-carboxymethyloxyphenyl)-4,5-dihydro-3(2H)-pyridazinone
Keywords: پیریدازینون; Hypertension; Pyridazinones; Hydrazine derivatives; Vasodilatory activity
Novel HCV NS5B polymerase inhibitors derived from 4-(1′,1′-dioxo-1′,4′-dihydro-1′λ6-benzo[1′,2′,4′]thiadiazin-3′-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 5: Exploration of pyridazinones containing 6-amino-substituents
Keywords: پیریدازینون; Pyridazinones; 5-Hydroxy-3(2H)-pyridazinone derivatives; Hepatitis C virus (HCV); RNA-dependent RNA polymerase (RdRp); Non-nucleoside NS5B inhibitors
2-Substituted 4-, 5-, and 6-[(1E)-3-oxo-3-phenylprop-1-en-1-yl]pyridazin-3(2H)-ones and 2-substituted 4,5-bis[(1E)-3-oxo-3-phenylprop-1-en-1-yl]pyridazin-3(2H)-ones as potent platelet aggregation inhibitors: Design, synthesis, and SAR studies
Keywords: پیریدازینون; Platelets; Pyridazinones; Chalcones; Antiplatelet agents
Novel HCV NS5B polymerase inhibitors derived from 4-(1′,1′-dioxo-1′,4′-dihydro-1′λ6-benzo[1′,2′,4′]thiadiazin-3′-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 1: Exploration of 7′-substitution of benzothiadiazine
Keywords: پیریدازینون; Pyridazinones; 5-Hydroxy-3(2H)-pyridazinone derivatives; Hepatitis C virus (HCV); Structure-based design; RNA-dependent RNA polymerase (RdRp); Small molecule, Non-nucleoside NS5B inhibitors
Novel HCV NS5B polymerase inhibitors derived from 4-(1′,1′-dioxo-1′,4′-dihydro-1′λ6-benzo[1′,2′,4′]thiadiazin-3′-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 2: Variation of the 2- and 6-pyridazinone substituents
Keywords: پیریدازینون; Pyridazinones; 5-Hydroxy-3(2H)-pyridazinone derivatives; Hepatitis C virus (HCV); Structure-based design; RNA-dependent RNA polymerase (RdRp); Small molecule; Non-nucleoside NS5B inhibitors
Novel HCV NS5B polymerase inhibitors derived from 4-(1′,1′-dioxo-1′,4′-dihydro-1′λ6-benzo[1′,2′,4′]thiadiazin-3′-yl)-5-hydroxy-2H-pyridazin-3-ones: Part 4. Optimization of DMPK properties
Keywords: پیریدازینون; Pyridazinones; 5-Hydroxy-3(2H)-pyridazinone derivatives; Hepatitis C virus (HCV); RNA-dependent RNA polymerase (RdRp); Small molecule; Non-nucleoside NS5B inhibitors; DMPK properties
Novel HCV NS5B polymerase inhibitors derived from 4-(1′,1′-dioxo-1′,4′-dihydro-1′λ6-benzo[1′,2′,4′]thiadiazin-3′-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 3: Further optimization of the 2-, 6-, and 7′-substituents and initial pharmacokinetic assessments
Keywords: پیریدازینون; Pyridazinones; 5-Hydroxy-3(2H)-pyridazinone derivatives; Hepatitis C virus (HCV); RNA-dependent RNA polymerase (RdRp); Small molecule; Non-nucleoside NS5B inhibitors; DMPK profiling; Ratio of liver to plasma concentration
Pyridazines part 41: Synthesis, antiplatelet activity and SAR of 2,4,6-substituted 5-(3-oxo-3-phenylprop-1-en-1-yl)- or 5-(3-phenylprop-2-enoyl)pyridazin-3(2H)-ones
Keywords: پیریدازینون; Platelets; Antiplatelet agents; Pyridazinones; Palladium
Pyridazine derivatives. Part 40: Reactivity of 5-alkynylpyridazin-3(2H)-ones toward hydrochloric acid
Keywords: پیریدازینون; Pyridazinones; Electrophilic addition; Protecting groups; X-ray diffraction;