Keywords: تمدید فاصله QT; Angina pectoris; Non-obstructive coronary artery disease; Coronary microvascular dysfunction; QT interval prolongation; T wave morphology;
مقالات ISI تمدید فاصله QT (ترجمه نشده)
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Population Pharmacokinetic/Pharmacodynamics Modeling of Ibutilide in Chinese Healthy Volunteers and Patients With Atrial Fibrillation (AF) and/or Atrial Flutter (AFL)
Keywords: تمدید فاصله QT; ibutilide; NONMEM; population PK and PK/PD model; QT interval prolongation; sigmoid Emax model;
Electrocardiographic predictors of coronary microvascular dysfunction in patients with non-obstructive coronary artery disease: Utility of a novel T wave analysis program
Keywords: تمدید فاصله QT; Non-obstructive coronary artery disease; Coronary microvascular dysfunction; QT interval prolongation; Ventricular arrhythmia; T wave morphology;
Coronary microvascular dysfunction is associated with baseline QTc prolongation amongst patients with chest pain and non-obstructive coronary artery disease
Keywords: تمدید فاصله QT; Non-obstructive coronary artery disease; Coronary microvascular dysfunction; QT interval prolongation; Ventricular arrhythmia; Cardiovascular events
Population Pharmacokinetic-Pharmacodynamic Analysis to Compare the Effect of Moxifloxacin on QT Interval Prolongation Between Healthy Korean and Japanese Subjects
Keywords: تمدید فاصله QT; ethnic difference; Japanese; Korean; moxifloxacin; QT interval prolongation;
Drug-induced QT interval prolongation: Do we know the risks?
Keywords: تمدید فاصله QT; QT interval prolongation; Torsade de pointes; Drugs; Risk factors; Drug interactionsProlongación del intervalo QT; Torsade de pointes; Fármacos; Factores de riesgo; Interacciones farmacológicas
Hypoglycaemia and QT interval prolongation in type 1 diabetes - bridging the gap between clamp studies and spontaneous episodes
Keywords: تمدید فاصله QT; Hypoglycaemia; QT interval prolongation; Type 1 diabetes; Dead in bed;
Anti-addiction drug ibogaine inhibits voltage-gated ionic currents: A study to assess the drug's cardiac ion channel profile
Keywords: تمدید فاصله QT; hERG; human Ether-Ã -go-go-Related Gene; 18-MC; 18-Methoxycoronaridine; AP; action potential; Anti-addiction drug; hERG potassium channels; Ibogaine; 18-Methoxycoronaridine; QT interval prolongation; Voltage-gated ion channels;
Effects of probucol, a typical hERG expression inhibitor, on in vivo QT interval prolongation in conscious dogs
Keywords: تمدید فاصله QT; Probucol; hERG expression inhibitor; QT interval prolongation; Conscious dogs
Galantamine (Reminyl®) delays cardiac ventricular repolarization and prolongs the QT interval by blocking the HERG current
Keywords: تمدید فاصله QT; Galantamine; Ventricular repolarization; QT interval prolongation; Action potential; HERG blocker
Beat-by-beat QT interval variability, but not QT prolongation per se, predicts drug-induced torsades de pointes in the anaesthetised methoxamine-sensitized rabbit
Keywords: تمدید فاصله QT; Rabbit; QT; QT interval prolongation; QT interval variability; Torsades de pointes
Sensitivity of common marmosets to detect drug-induced QT interval prolongation: Moxifloxacin case study
Keywords: تمدید فاصله QT; Common marmoset; Telemetry; Moxifloxacin; QT interval prolongation; Probabilistic QT analysis; Safety pharmacology
Unclear loss of consciousness after clobutinol intake
Keywords: تمدید فاصله QT; Clobutinol; Unconsciousness; Munchausen syndrome by proxy; Forensic-toxicological analyses; QT interval prolongation; Side effect
Age-related differences of QT interval and autonomic nervous system activity in female cynomolgus monkeys
Keywords: تمدید فاصله QT; Age; Autonomic nervous system activity; Cynomolgus monkey; Methods; QT interval; QT interval prolongation; Sotalol
Evaluation of drug-induced QT prolongation in a halothane-anesthetized monkey model: Effects of sotalol
Keywords: تمدید فاصله QT; Cynomolgus monkey; Halothane; Methods; Monophasic action potential; QT interval prolongation; Sotalol; Ventricular pacing
Comparison of electrocardiographic analysis for risk of QT interval prolongation using safety pharmacology and toxicological studies
Keywords: تمدید فاصله QT; ECG, electrocardiogram; GLP, Good Laboratory Practice; hERG, human ether-a-go-go related gene; ICH, International Conference on Harmonizaton; TQT, clinical thorough QT/QTc prolongation studyhERG; QT interval prolongation; Electrocardiogram; Safety pharmac
Beat-to-beat variability of repolarization differentiates the extent of torsadogenic potential of multi ion channel-blockers bepridil and amiodarone
Keywords: تمدید فاصله QT; Bepridil; QT interval prolongation; Torsades de pointes; Beat-to-beat variability of repolarization; Chronic atrioventricular block dog
Relevance of in vitro SCREENIT results for drug-induced QT interval prolongation in vivo: A database review and analysis
Keywords: تمدید فاصله QT; APD; action potential duration; ECG; electrocardiogram; hERG; human ether-a-gogo related gene; MAP; monophasic action potential; QTc; corrected QT interval on ECG; TdP; torsade de pointes; VT; ventricular tachycardia; VF; ventricular fibrillation; TRIaD;
Identification of “toxicophoric” features for predicting drug-induced QT interval prolongation
Keywords: تمدید فاصله QT; hERG K+ channel; Toxicophore; QT interval prolongation; Molecular modeling; Homology building
Safety and secondary pharmacology: Successes, threats, challenges and opportunities
Keywords: تمدید فاصله QT; Safety pharmacology; Pharmacological profiling; Adverse drug reactions; QT interval prolongation
K201, a multi-channel blocker, inhibits clofilium-induced torsades de pointes and attenuates an increase in repolarization
Keywords: تمدید فاصله QT; K201 (JTV-519); Multi-channel blocker; Clofilium; α1-Adrenoceptor blocker; QT interval prolongation; Torsades de pointes;
Monophasic action potential in anaesthetized guinea pigs as a biomarker for prediction of liability for drug-induced delayed ventricular repolarization
Keywords: تمدید فاصله QT; Monophasic action potential; Anaesthetized guinea pigs; MAP90; QT interval prolongation; Methods; Screening; Safety pharmacology
Cardiotoxicity reduction induced by halofantrine entrapped in nanocapsule devices
Keywords: تمدید فاصله QT; QT interval prolongation; Halofantrine; Nanocapsules; Drug carriers; Cardiotoxicity; Lipophilic drug;
The efficacy and cardiac evaluation of aminomethyl tetrahydronaphthalene ketopiperazines: A novel class of potent MCH-R1 antagonists
Keywords: تمدید فاصله QT; Melanin-concentrating hormone; MCH R1 antagonists; Obesity; hERG; QT interval prolongation
Electrophysiological effects of brompheniramine on cardiac ion channels and action potential
Keywords: تمدید فاصله QT; Antihistamine; Brompheniramine; hERG; Action potential; QT interval prolongation
Use of in vitro methods to predict QT prolongation
Keywords: تمدید فاصله QT; QT interval prolongation; hERG; Proarrhythmia;