Characterization of the enzymatic activity of Clostridium perfringens TpeL
Keywords: Clostridium perfringens; Toxin; TpeL; Rho-GTPases; Ras; Rac;
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Comparative life cycle assessment (LCA) of raising rainbow trout (Oncorhynchus mykiss) in different production systems
Keywords: AP; acidification potential; CML; Center for Environmental Studies, University of Leiden; EP; eutrophication potential; ES; extensive flow-through production system; GWP; global warming potential; IS; intensive flow through production system; ISO; Interna
Activation of ERK signaling and induction of colon cancer cell death by piperlongumine
Keywords: ERK; extracellular-signal-regulated kinase; RAS; rat sarcoma oncogene; MAPK; mitogen-activated protein kinase; MEK; mitogen-activated protein kinase; PPLGM; piperlongumine; ROS; reactive oxygen species; Piperlongumine; Colon cancer; MEK/ERK; Cell signalin
Regulator of G protein signaling 19 suppresses Ras-induced neoplastic transformation and tumorigenesis
Keywords: ERK; GAIP; Nm23; Ras; RGS19;
Combined CpG and poly I:C stimulation of monocytes results in unique signaling activation not observed with the individual ligands
Keywords: TLRs; Toll-like receptors; CpG; unmethylated CpG oligodeoxynucleotides; poly I:C; polyinosinic-polycytidylic acid; NO; nitric oxide; iNOS; inducible nitric oxide synthase; CREB; cAMP response element-binding protein; NFκB; nuclear factor κB; PRRs; pat
Expression and cytoprotective activity of the small GTPase RhoB induced by the Escherichia coli cytotoxic necrotizing factor 1
Keywords: CNF1; cytotoxic necrotizing factor from E. coli; CNF1; cytotoxic necrotizing factor from Y. pseudotuberculosis; TcdA; Toxin A from C. difficile strain; TcdB; Toxin B from C. difficile strain; TcsL; Lethal Toxin from C. sordellii; Deamidation; Cytokinesis;
Chronic AT2 receptor activation increases renal ACE2 activity, attenuates AT1 receptor function and blood pressure in obese Zucker rats
Keywords: CGP42112A; obesity; RAS; renin AT2 receptor;
Nitrogen-containing bisphosphonates induce apoptosis of hematopoietic tumor cells via inhibition of Ras signaling pathways and Bim-mediated activation of the intrinsic apoptotic pathway
Keywords: Nitrogen-containing bisphosphonates; Bim; Ras; ERK1/2; mTOR;
The role of Src protein in the process formation of PC12 cells induced by the proteasome inhibitor MG-132
Keywords: Cy3; Â a fluorophor cyanin dye; DMEM; Â Dulbecco's Modified Eagle's Medium; DMSO; Â dimethyl-sulfoxyde; EDTA; Â ethylenediaminetetraacetic acid; EGTA; Â ethylene glycol tetraacetic acid; ERK1/2; Â extracellular signal-regulated kinase 1 and 2; H-Ras;
Negative regulation of Shh levels by Kras and Fgfr2 during hair follicle development
Keywords: Hair follicle; Shh; RAS; FGF; Morphogen; Signal strength; Amplitude;
Angiotensin AT2 receptor activates the cyclic-AMP signaling pathway in eel
Keywords: ATIP; AT2 receptor interacting protein; CRE; cAMP-responsive element; DIG; digoxigenin; GC; guanylyl cyclase; GPCR; G-protein coupled receptor; HEK293; human embryonic kidney cell line 293; KT5823; 2,3,9,10,11,12-hexahydro-10R-methoxy-2,9-dimethyl-1-oxo-9
Ras activation mediates WISP-1-induced increases in cell motility and matrix metalloproteinase expression in human osteosarcoma
Keywords: WISP-1; Migration; Osteosarcoma; Ras; Raf-1;
MEK-1 activates C-Raf through a Ras-independent mechanism
Keywords: Raf; Ras; MEK; ERK; MAPK; Phosphorylation;
Angiotensin (5-8) modulates nociception at the rat periaqueductal gray via the NO-sGC pathway and an endogenous opioid
Keywords: AA; antinociceptive activity; Angs; angiotensins; Ang-R; Ang receptor; ANOVA; analysis of variance; AT; Ang type; ATR; Ang type receptor; DMSO; dimethylsulfoxide; HR; heart rate; MAP; mean arterial pressure; nNOS; neuronal nitric oxide synthase; NO; nitri
Design, dimensioning, and performance of a research facility for studies on the requirements of fish in RAS environments
Keywords: BW; body weight; CO2; carbon dioxide; COD; chemical oxygen demand; DO; dissolved oxygen; DM; dry matter; FT; flow-through; GRP; glass-fiber reinforced plastic; GSM; global system for mobile communication; HDPE; high-density polyethylene; HLR; hydraulic lo
Adenosine dialdehyde suppresses MMP-9-mediated invasion of cancer cells by blocking the Ras/Raf-1/ERK/AP-1 signaling pathway
Keywords: Transmethylation; Adenosine dialdehyde; AP-1; Ras; Isoprenyl carboxyl methyltransferase; S-adenosylhomocysteine hydrolase;
APC loss-induced intestinal tumorigenesis in Drosophila: Roles of Ras in Wnt signaling activation and tumor progression
Keywords: Adenomatous polyposis coli (APC); Wnt; Ras; Tumorigenesis; DE-cadherin; Drosophila;
The “self cleaning inherent gas denitrification-reactor” for nitrate elimination in RAS for pike perch (Sander lucioperca) production
Keywords: Denitrification; RAS; Moving bed; Pike perch; Feed intake;
RAS mutation analysis in a large cohort of Chinese patients with acute myeloid leukemia
Keywords: RAS; mutation; acute myeloid leukemia; Chinese
Commercial land-based farming of European lobster (Homarus gammarus L.) in recirculating aquaculture system (RAS) using a single cage approach
Keywords: Lobster farming; RAS; Management
Ral GTPases in tumorigenesis: Emerging from the shadows
Keywords: RalA; RalB; Ras; RalGEF; RalBP1; Exocyst
Effect of RAS inhibition on TGF-β, renal function and structure in experimentally induced diabetic hypertensive nephropathy rats
Keywords: TGF-β; RAS; Fibrosis; Diabetic hypertensive rat
Microbial toxicity of the insensitive munitions compound, 2,4-dinitroanisole (DNAN), and its aromatic amine metabolites
Keywords: DNAN; 2,4-dinitroanisole; MENA; 2-methoxy-5-nitroaniline; DAAN; 2,4-diaminoanisole; TNT; 2,4,6-trinitrotoluene; IC50; 50% inhibition concentration; RAS; return activated sludge; VSS; volatile suspended solids; 2,4-Dinitroanisole; 2-Methoxy-5-nitroaniline;
High nuclear expression of phosphorylated extracellular signal–regulated kinase in tumor cells in colorectal glands is associated with poor outcome in colorectal cancer
Keywords: Colorectal adenomas; Colorectal cancer; ERK; Nuclear; Phosphorylation; Ras
Waste treatment in recirculating aquaculture systems
Keywords: Recirculating aquaculture systems; RAS; Waste treatment; Waste production; Onsite treatment; Waste disposal
ROS, autophagy, mitochondria and cancer: Ras, the hidden master?
Keywords: Autophagy; Mitochondria; ROS; Ras; Metabolism
Effects of sub-lethal CO2(aq) concentrations on the performance of intensively reared gilthead seabream (Sparus aurata) in brackish water: Flow-through experiments and full-scale RAS results
Keywords: FCR, food conversion ratio; GR, growth rate; NIST, National Institute of Standards; NBS, National Bureau of Standards; NPF, no pathogens found; SGR, specific growth rate; SG, splenic granulomaGilthead seabream; CO2 sub-lethal effect; Growth rate; RAS; Def
The natural product honokiol inhibits calcineurin inhibitor-induced and Ras-mediated tumor promoting pathways
Keywords: Honokiol; Ras; VEGF; HO-1; Renal tumor
End-of-pipe denitrification using RAS effluent waste streams: Effect of C/N-ratio and hydraulic retention time
Keywords: RAS; Denitrification; Sludge hydrolysis; Volatile fatty acids
Acute and chronic nitrite toxicity in juvenile pike-perch (Sander lucioperca) and its compensation by chloride
Keywords: Pike-perch; RAS; Nitrite; Toxicity; Histology; Methemoglobin; Methemoglobinemia; Animal welfare; Nitrification;
Transient high level mammalian reovirus replication in a bat epithelial cell line occurs without cytopathic effect
Keywords: Reovirus; Bat; Persistence; Interferon; Ras
Ras and extracellular signal-regulated kinase signaling in thymocytes and T cells
Keywords: Ras; extracellular signal-regulated kinase; PAK; Bam32; Sos; phospholipase C-γ1
Contributions of KRAS and RAL in Non–Small-Cell Lung Cancer Growth and Progression
Keywords: RAL; RAS; Non–small-cell lung cancer; GTPase; Prognosis
TNF-related weak inducer of apoptosis (TWEAK) promotes kidney fibrosis and Ras-dependent proliferation of cultured renal fibroblast
Keywords: Kidney fibrosis; Fn14; TWEAK; Ras; Proliferation; NFκB
Guggulsterone sensitizes glioblastoma cells to Sonic hedgehog inhibitor SANT-1 induced apoptosis in a Ras/NFκB dependent manner
Keywords: Guggulsterone; NFκB; Ras; Shh; Glioblastoma
Crystal structures of the state 1 conformations of the GTP-bound H-Ras protein and its oncogenic G12V and Q61L mutants
Keywords: GAP; GTPase-activating protein; GppNHp; guanosine 5â²-(β,γ-imido)triphosphate; RBD; Ras-binding domain; WT; Wild type; rms; root mean square; Ras; Small GTPases; Oncogene; Crystal structure; Conformational dynamics;
Expression of RAS-like family members, c-jun and c-myc mRNA levels in neoplastic hemocytes of soft-shell clams Mya arenaria using microsphere-based 8-plex branched DNA assay
Keywords: Hemocytes; Multiplex; RAS; c-myc; c-jun; Tetraploidy
Resequencing analysis of the candidate tyrosine kinase and RAS pathway gene families in multiple myeloma
Keywords: Multiple myeloma; tyrosine kinase; RAS; resequencing; mutation analysis; cancer
The chronic effect of nitrate on production performance and health status of juvenile turbot (Psetta maxima)
Keywords: Nitrate; Toxicity; Marine; RAS; Turbot
Neoadjuvant chemotherapy modifies serum angiotensinase activities in women with breast cancer
Keywords: APN; aminopeptidase N; APB; aminopeptidase B; ASAP; aspartil aminopeptidase; APA; aminopeptidase A; RAS; renin-angiotensin system; Ang II; angiotensin II; Ang IV; angiotensin IV; Breast cancer; Renin angiotensin system; Aminopeptidases; Chemotherapy;
Consequences of RAS and MAPK activation in the ovary: The good, the bad and the ugly
Keywords: RAS; MAPKs; Ovary; Ovulation; Ovarian cancer
Depletion of CSN5 inhibits Ras-mediated tumorigenesis by inducing premature senescence in p53-null cells
Keywords: CSN5; COP9 signalosome; Ras; p53; Tumorigenesis; Senescence; Cell cycle;
Renin–angiotensin system genes polymorphism in Egyptians with premature coronary artery disease
Keywords: RAS; Genetic polymorphism; Premature CAD
RAS oncogenic signal upregulates EZH2 in pancreatic cancer
Keywords: Pancreatic cancer; RAS; EZH2; RUNX3;
Research ReportActivation of Ras/MEK/ERK signaling in chronic subdural hematoma outer membranes
Keywords: CSDH; chronic subdural hematoma; ERK; extracellular signal-regulated kinase; GAP; GTPase-activating protein; MEK; extracellular signal-regulated kinase kinase; VEGF; vascular endothelial growth factor; Chronic subdural hematoma; ERK; MEK; Ras;
Changes in actin and E-cadherin expression induced by 5-aminolevulinic acid photodynamic therapy in normal and Ras-transfected human mammary cell lines
Keywords: Photodynamic therapy (PDT); Aminolevulinic acid (ALA); Cytoskeleton; Actin; Ras; E-cadherin
The role of autophagy in cytotoxicity induced by new oncogenic B-Raf inhibitor UI-152 in v-Ha-ras transformed fibroblasts
Keywords: B-Raf inhibitor; UI-152; Ras; Autophagy; Apoptosis;
Casitas B-cell lymphoma mutation in childhood T-cell acute lymphoblastic leukemia
Keywords: CBL; Acute lymphoblastic leukemia; Noonan syndrome; RAS; NOTCH;
Protective role of the vitamin D receptor
Keywords: VDR; vitamin D receptor; RAS; renin-angiotensin system; VDRA; vitamin D receptor agonists; VDRE; vitamin D response elements; RXR; retinoid X receptors; SRC; steroid receptor activator complex; DRIP; vitamin D receptor interacting protein complex; NCoR; n
Inhibition of the renin-angiotensin system downregulates tissue factor and vascular endothelial growth factor in human breast carcinoma cells
Keywords: ACE; angiotensin-converting enzyme; EIA; enzyme immuno assay; ELISA; enzyme linked immunosorbent assay; PAR; protease activated receptor; RAS; renin-angiotensin system; RT-PCR; Real-Time reverse transcriptase polymerase chain reaction; TF; tissue factor;