Keywords: سلول های اپیتلیال رنگدانه شبکیه; GLP-1; glucagon-like peptide-1; GLP-1RA; glucagon-like peptide-1 receptor agonists; DR; diabetic retinopathy; VEGF; vascular endothelial growth facto; DM; diabetes mellitus; Ops; oscillatory potentials; E4; Exenatide-4; GCL; ganglion cell layer; RGC; Reti
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Keywords: سلول های اپیتلیال رنگدانه شبکیه; AMD; age-related macular degeneration; ARPE; arising retinal pigment epithelial cells; b-FGF; basic fibroblast growth factor; BSA; bovine serum albumin; BDNF; brain-derived neurotrophic factor; CNS; Central Nervous System; CNTF; ciliary neurotrophic facto
Keywords: سلول های اپیتلیال رنگدانه شبکیه; Polymers; Ocular drug delivery; Nanoparticles; Microparticles; Gels; Ocular bioavailability; ABC; ATP-binding cassette superfamily; ANDA; Abbreviated new drug application; AUC; Area-under-the-curve; BSA; Bovine serum albumin; DDS; Drug delivery system; EP
Keywords: سلول های اپیتلیال رنگدانه شبکیه; Human embryonic stem cells; Retinal pigment epithelial cells; Phototoxicity; Alternative test method;
Keywords: سلول های اپیتلیال رنگدانه شبکیه; α-syn; alpha synuclein; Tf; transferrin; TfR; transferrin receptor; DA; dopamine; PD; Parkinson's disease; Tf-Fe; transferrin bound iron; NTBI; non transferrin bound iron; SN; substantia nigra; RPE; retinal pigment epithelium; OCT; optical coherence tomo
Keywords: سلول های اپیتلیال رنگدانه شبکیه; epiretinal membrane; myofibroblast; retinal detachment; retinal pigment epithelial cells; wound healing
Keywords: سلول های اپیتلیال رنگدانه شبکیه; hBMSC; human bone marrow-derived stem cells; BM; bone marrow; mPB; mobilized peripheral blood; hRPE; human retinal pigment epithelium; AMD; age-related macular degeneration; POS; photoreceptor outer segments; FACS; fluorescence-activated cell sorting; MAC
Keywords: سلول های اپیتلیال رنگدانه شبکیه; Diabetic retinopathy; Protein arginine methyltransferase; Coactivator-associated arginine methyltransferase 1; CARM1; Apoptosis; Retinal pigment epithelial cells;
Keywords: سلول های اپیتلیال رنگدانه شبکیه; Sphingomyelinase; Endoplasmic reticulum stress; Nitric oxide; Retinal pigment epithelial cells; Free radicals;
Keywords: سلول های اپیتلیال رنگدانه شبکیه; Retinal pigment epithelial cells; Proliferative vitreoretinopathy; Tacrolimus; Transforming growth factor β; Oligonucleotide microarray
Knockdown of survivin results in inhibition of epithelial to mesenchymal transition in retinal pigment epithelial cells by attenuating the TGFβ pathway
Keywords: سلول های اپیتلیال رنگدانه شبکیه; BIRC5; Survivin; Lentiviral CRISPR/Cas9 nickase vector; YM155; Retinal pigment epithelial cells; Epithelial to mesenchymal transition (EMT);
A cell penetrating peptide from SOCS-1 prevents ocular damage in experimental autoimmune uveitis
Keywords: سلول های اپیتلیال رنگدانه شبکیه; Immune suppression; Autoimmune uveitis; Retinal pigment epithelial cells; Mouse model; Ocular inflammation;
Artemisinin protects human retinal pigment epithelial cells from hydrogen peroxide-induced oxidative damage through activation of ERK/CREB signaling
Keywords: سلول های اپیتلیال رنگدانه شبکیه; Retinal pigment epithelial cells; Age-related macular degeneration; Artemisinin; ROS; ERK;
MicroRNA-29b regulates TGF-β1-mediated epithelial-mesenchymal transition of retinal pigment epithelial cells by targeting AKT2
Keywords: سلول های اپیتلیال رنگدانه شبکیه; MicroRNA-29b; Retinal pigment epithelial cells; Akt2; EMT;
The novel triterpenoid RTA 408 protects human retinal pigment epithelial cells against H2O2-induced cell injury via NF-E2-related factor 2 (Nrf2) activation
Keywords: سلول های اپیتلیال رنگدانه شبکیه; Retinal pigment epithelial cells; Oxidative stress; RTA 408; Nrf2
Autophagy in the eye: Development, degeneration, and aging
Keywords: سلول های اپیتلیال رنگدانه شبکیه; Autophagy; Retina; Chaperone mediated autophagy; Lysosomes; Mitophagy; Retinal ganglion cells; Retinal pigment epithelial cells; Photoreceptor; Glaucoma; Macular degeneration; Retinal dystrophies; Diabetic retinopathy; 3-MA; 3-methyl adenine; 8-OH DPAT; 8
Notch signaling regulates M2 type macrophage polarization during the development of proliferative vitreoretinopathy
Keywords: سلول های اپیتلیال رنگدانه شبکیه; Macrophages; Notch signaling; Proliferative vitreoretinopathy; Retinal pigment epithelial cells; Wound healing;
Human retinal pigment epithelial cell proliferation by the combined stimulation of hydroquinone and advanced glycation end-products via up-regulation of VEGF gene
Keywords: سلول های اپیتلیال رنگدانه شبکیه; AGE; advanced glycation endproduct; AMD; age-related macular degeneration; BSA; bovine serum albumin; ELISA; enzyme-linked immunosorbent assay; FCS; fetal calf serum; HQ; hydroquinone; IdU; 5ʹ-Indo-2ʹ-deoxyuridine; RAGE; receptor for advanced glycation
Nrf2 activators modulate oxidative stress responses and bioenergetic profiles of human retinal epithelial cells cultured in normal or high glucose conditions
Keywords: سلول های اپیتلیال رنگدانه شبکیه; Carnosol (PubChem CID: 442009); Dimethyl fumarate (PubChem CID: 637568); Nrf2; Nuclear factor (erythroid-derived 2)-like 2; DMF; dimethylfumarate; NG; normal glucose; HG; high glucose; ROS; reactive oxygen species; HO-1; heme oxygenase-1; SnPPIX; tin prot
Regulation of the cholesterol efflux transporters ABCA1 and ABCG1 in retina in hemochromatosis and by the endogenous siderophore 2,5-dihydroxybenzoic acid
Keywords: سلول های اپیتلیال رنگدانه شبکیه; RPE; retinal pigment epithelium; ABCA1; ATP-binding cassette transporter A1; ABCG1; ATP-binding cassette transporter G1; Bdh2; β-hydroxybutyrate dehydrogenase-2; 2,5-DHBA; 2,5-dihydroxybenzoic acid; AMD; age-related macular degeneration; pRPE; primary cu
Hyperglycemia promotes vasculogenesis in choroidal neovascularization in diabetic mice by stimulating VEGF and SDF-1 expression in retinal pigment epithelial cells
Keywords: سلول های اپیتلیال رنگدانه شبکیه; age-related macular degeneration; bone marrow-derived cells; diabetes mellitus; retinal pigment epithelial cells; AMD; age-related macular degeneration; BMCs; bone marrow-derived cells; BMSCs; bone marrow-derived mesenchymal stem cells; CNV; choroidal neo
Decorin inhibits angiogenic potential of choroid-retinal endothelial cells by downregulating hypoxia-induced Met, Rac1, HIF-1α and VEGF expression in cocultured retinal pigment epithelial cells
Keywords: سلول های اپیتلیال رنگدانه شبکیه; choroidal neovascularization; decorin; Met; vascular endothelial growth factor; retinal pigment epithelial cells; hypoxia;
Complement expression in retinal pigment epithelial cells is modulated by activated macrophages
Keywords: سلول های اپیتلیال رنگدانه شبکیه; complement; retinal pigment epithelial cells; macrophages
Molecular expression and functional activity of efflux and influx transporters in hypoxia induced retinal pigment epithelial cells
Keywords: سلول های اپیتلیال رنگدانه شبکیه; Efflux and influx transporters; Hypoxia; Molecular expression and functional activity; Retinal pigment epithelial cells
Vitreous-induced cytoskeletal rearrangements via the Rac1 GTPase-dependent signaling pathway in human retinal pigment epithelial cells
Keywords: سلول های اپیتلیال رنگدانه شبکیه; PVR; proliferative vitreoretinopathy; RPE; retinal pigment epithelial cells; ERM; epiretinal membrane; EMT; epithelial-mesenchymal transdifferentiation; LIMK; LIM kinase; Cytoskeletal rearrangement; Rac1 GTPase; Vitreous; Human retinal pigment epithelia
Viability of freeze dried microencapsulated human retinal pigment epithelial cells
Keywords: سلول های اپیتلیال رنگدانه شبکیه; Freeze drying; Retinal pigment epithelial cells; Cell microcapsulation; Cell therapy; Trehalose; Alginate;
ReviewThe immunological challenges of cell transplantation for the treatment of Parkinson's disease
Keywords: سلول های اپیتلیال رنگدانه شبکیه; Dopamine; Nigrostriatal degeneration; Central nervous system; Immunosuppression; Stem cells; Retinal pigment epithelial cells;
TGF-β-stimulated aberrant expression of class III β-tubulin via the ERK signaling pathway in cultured retinal pigment epithelial cells
Keywords: سلول های اپیتلیال رنگدانه شبکیه; Class III β-tubulin; Retinal pigment epithelial cells; Transforming growth factor-β; Proliferative vitreoretinopathy;
Erythropoietin protects retinal pigment epithelial cells against the increase of permeability induced by diabetic conditions: Essential role of JAK2/ PI3K signaling
Keywords: سلول های اپیتلیال رنگدانه شبکیه; Erythropoietin; Diabetic macular edema; Permeability; Retinal pigment epithelial cells; JAK2; PI3K/AKT
Pigment epithelium derived factor (PEDF) is neuroprotective in two in vitro models of Parkinson's disease
Keywords: سلول های اپیتلیال رنگدانه شبکیه; Retinal pigment epithelial cells; Dopaminergic neurons; Trophic factors; Neurite length; Cell transplantation; Pigment epithelium derived factor;
Focal adhesion kinase signaling pathway participates in the formation of choroidal neovascularization and regulates the proliferation and migration of choroidal microvascular endothelial cells by acting through HIF-1 and VEGF expression in RPE cells
Keywords: سلول های اپیتلیال رنگدانه شبکیه; focal adhesion kinase; choroidal neovascularization; retinal pigment epithelial cells; hypoxia; signal transduction; choroidal microvascular endothelial cells
Spheramine for Treatment of Parkinson's Disease
Keywords: سلول های اپیتلیال رنگدانه شبکیه; Parkinson's disease; retinal pigment epithelial cells; neurotherapeutics; neurodegeneration; cellular therapies; cell transplantation;
Alginate-based microencapsulation of retinal pigment epithelial cell line for cell therapy
Keywords: سلول های اپیتلیال رنگدانه شبکیه; Cell encapsulation; Alginate; Protein release; Retinal pigment epithelial cells; ARPE-19
Alterations of activity and intracellular distribution of the 20S proteasome in ageing retinal pigment epithelial cells
Keywords: سلول های اپیتلیال رنگدانه شبکیه; Proteasome; Ageing; Redistribution; Retinal pigment epithelial cells; Age-related macular degeneration
The involvement of phosphatidylinositol 3-kinase /Akt signaling in high glucose-induced downregulation of GLUT-1 expression in ARPE cells
Keywords: سلول های اپیتلیال رنگدانه شبکیه; Diabetic retinopathy; Retinal pigment epithelial cells; PI-3 kinase/Akt; Protein kinase C
Effect of magnolol on TGF-β1 and fibronectin expression in human retinal pigment epithelial cells under diabetic conditions
Keywords: سلول های اپیتلیال رنگدانه شبکیه; Diabetic retinopathy; TGF-β1; Fibronectin; Retinal pigment epithelial cells; Magnolol; High glucose; S100b
Geldanamycin, a HSP90 inhibitor, attenuates the hypoxia-induced vascular endothelial growth factor expression in retinal pigment epithelium cells in vitro
Keywords: سلول های اپیتلیال رنگدانه شبکیه; retinal pigment epithelial cells; hypoxia; vascular endothelial growth factor; heat shock proteins; geldanamycin
Synthesis of complement factor H by retinal pigment epithelial cells is down-regulated by oxidized photoreceptor outer segments
Keywords: سلول های اپیتلیال رنگدانه شبکیه; complement; complement factor H; age-related macular degeneration; retinal pigment epithelial cells; photoreceptor outer segment; cytokine
Synthetic carotenoid derivatives prevent photosensitised killing of retinal pigment epithelial cells more effectively than lutein
Keywords: سلول های اپیتلیال رنگدانه شبکیه; cationic carotenoid derivatives; lysosomes; macular degeneration; photoprotection; retinal pigment epithelial cells; singlet oxygenA2E, 2-[2,6-dimethyl-8-(2,6,6-trimethyl-1-cyclohexen-1-yl)-1E,3E,5E,7E-octatetraenyl]-1-(2-hydroxyethyl)-4-[4-methyl-6(2,6,6
High glucose concentration induces elevated expression of anti-oxidant and proteolytic enzymes in cultured human retinal pigment epithelial cells
Keywords: سلول های اپیتلیال رنگدانه شبکیه; proteomics; retinal pigment epithelial cells; hyperglycemia; two-dimensional electrophoresis; mass spectrometry; oxidative stressMALDI-TOF MS, matrix-assisted laser desorption/ionization time-of-flight mass spectrometry; IEF, isoelectric focusing; PMF, pe
15-Deoxy-12,14-prostaglandin J2 inhibits interferon gamma induced MHC class II but not class I expression on ARPE cells through a PPAR gamma independent mechanism
Keywords: سلول های اپیتلیال رنگدانه شبکیه; 15-Deoxy-12,14-prostaglandin J2; Retinal pigment epithelial cells; Inflammation; Interferon gamma; MHC class II; PPARγ
Signaling pathways involved in PDGF-evoked cellular responses in human RPE cells
Keywords: سلول های اپیتلیال رنگدانه شبکیه; Retinal pigment epithelial cells; PDGF stimulation; Proliferation; Chemotaxis; VEGF expression; ERK1/2; p38 MAPK; PI3K
Retinal pigment epithelial cell transplantation could provide trophic support in Parkinson's disease: Results from an in vitro model system
Keywords: سلول های اپیتلیال رنگدانه شبکیه; Retinal pigment epithelial cells; Parkinson's disease; Pigment-epithelial derived factor; Striatal neurons; Dopaminergic neurons; Trophic factors; Neurite length; Levodopa; Tyrosinase; Cell transplantation
Different death stimuli evoke apoptosis via multiple pathways in retinal pigment epithelial cells
Keywords: سلول های اپیتلیال رنگدانه شبکیه; apoptosis; retinal pigment epithelial cells; oxidation; cytotoxic T lymphocytes; fasAg, antigen; AIF, apoptosis inducing factor; CMF-PBS, Ca+2/Mg+2-free phosphate buffered saline; CTL, cytotoxic T lymphocytes; CuZnSOD, copper zinc superoxide dismutase; DM
Toxicity of oxidized β-carotene to cultured human cells
Keywords: سلول های اپیتلیال رنگدانه شبکیه; retinal pigment epithelial cells; K562 cells; carotenoid derived aldehydes; oxidative stress; β-carotene;
Resveratrol reduces oxidation and proliferation of human retinal pigment epithelial cells via extracellular signal-regulated kinase inhibition
Keywords: سلول های اپیتلیال رنگدانه شبکیه; AMD; age-related macular degeneration; BrdU; bromodeoxyuridine; DCF; dichlorofluorescein; DCFDA; 2â²,7â²-dichlorofluorescin diacetate; DCFH; dichlorofluorescin; ERK 1/2; extracellular signal-regulated kinase; MAPK; mitogen-activated protein kinase; MEK;
The fibroblast growth factor receptors, FGFR-1 and FGFR-2, mediate two independent signalling pathways in human retinal pigment epithelial cells
Keywords: سلول های اپیتلیال رنگدانه شبکیه; Fibroblast growth factor receptors; L-type calcium channels; bFGF-induced-c-fos expression; Neovascularisation; Age-related macular degeneration; Retinal pigment epithelial cells;
Selective and efficient culturing of retinal pigment epithelial cells using a feeder layer
Keywords: سلول های اپیتلیال رنگدانه شبکیه; conditioned medium; feeder layer; retinal pigment epithelial cells; 3T3-J2;