
A novel small-molecule YLT256 inhibits proliferation and induces apoptosis both in vitro and in vivo in solid tumors
Keywords: Bcl-2, B-cell lymphoma 2; Bak, Bcl-2 antagonist/killer-1; ΔΨm, mitochondrial membrane potential; ROS, reactive oxygen species; MTT, 3-(4,5-dimethyl-2-thiazolyl)-2,5-di-phenyl-2H-tetrazoliumbromide; PI, propidium iodide; Rh123, rhodamine-123; DCFA-DA, 2′7′