Targeting a marker of the tumour neovasculature using a novel anti-human CD105-immunotoxin containing the non-toxic type 2 ribosome-inactivating protein nigrin b
Keywords: IC50, concentration of inhibitor that affords 50% inhibition of the biologic activity; RIP(s), ribosome-inactivating protein(s); hCD105, human CD105; mCD105, mouse CD105; SPDP, N-succinimidyl-3-(2-pyridyldithio)-propionate; mAb, monoclonal antibodyNigrin