R-Loop Depletion by Over-expressed RNase H1 in Mouse B Cells Increases Activation-Induced Deaminase Access to the Transcribed Strand without Altering Frequency of Isotype Switching
Keywords: R-loops; somatic hypermutation; class switch recombination; RNase H1; transgenic mouse; CSR; class switch recombination; SHM; somatic hypermutation; Tg; transgenic; TCR; T-cell receptor; LPS; lipopolysaccharide; IL4; interleukin 4; pol II; polymerase II;