Fasudil, a Rho kinase inhibitor, promotes the autophagic degradation of A53T α-synuclein by activating the JNK 1/Bcl-2/beclin 1 pathway
Keywords: ROCK، Rho kinase; α-syn, α-synuclein; PD, Parkinson׳s disease; ROCK, Rho kinase; WT, wild-type; LBs, Lewy bodies; UPS, ubiquitin proteasome system; BSA, bovine serum albumin; CMA, chaperone-mediated autophagy; 3-MA, 3-methyladenine; Co-IP, Co-Immunoprecipitation; TEM, Tran