
Influence of methionine oxidation on the aggregation of recombinant human growth hormone
Keywords: r-hGH, recombinant human growth hormone; UV–Vis, ultraviolet–visible; 1,8-ANS, 1-anilinonaphthalene-8-sulfonic acid; RP-HPLC, reverse phase high pressure liquid chromatography; SEC, size exclusion chromatography; RT, room temperatureAggregation; Methionin