Superoxide anion mediated mitochondrial dysfunction leads to hepatocyte apoptosis preferentially in the periportal region during copper toxicity in rats
Keywords: CuSO4, copper sulphate; RPMI 1640, Roswell Park Memorial Institute 1640; FBS, fetal bovine serum; ALT, alanine transaminase; PP, periportal; PV, perivenous; HEPES, N-(2-hydroxyethyl)-piperazine-N′-2-ethanesulphonic acid; EDTA, ethylene diamine tetraacetic