Keywords: SHR; spontaneously hypertensive rats; DCE; dried chokeberry fruit extract; ROS; reactive oxygen species; SAP; systolic arterial pressure; DAP; diastolic arterial pressure; MAP; mean arterial pressure; PP; pulse pressure; CI; cardiac index; HR; heart rate;
مقالات ISI (ترجمه نشده)
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Keywords: MetS; metabolic syndrome; GFR; glomerular filtration rate; ROS; reactive oxygen species; Ox-LDL; oxidized low-density lipoprotein; ELAM; elamipretide; mPTP; mitochondrial permeability transition pore; PBS; phosphate-buffered saline; PRA; plasma renin acti
Keywords: Alcohol-free red wine; Anthocyanins; Malvidin-3-O-glucoside; Blood pressure; Oxidative stress; Magnesium; RW; red wine; AFRW; alcohol-free red wine; ROS; reactive oxygen species; SHR; spontaneously hypertensive rats; eNOS; endothelial nitric oxide synthas
Keywords: SNPs; Single nucleotide polymorphisms; IFNL3; interferon lambda 3; SVR; sustained virologic response; HCV-2/3; Hepatitis C virus genotype 2 and 3; RVR; rapid virological response; OR; odds ratio; PegIFNα/RBV; pegylated interferon-alpha and ribavirin; CHC
Safety and Efficacy of Sofosbuvir and Daclatasvir for Hepatitis C Virus Infection in Patients with β-Thalassemia Major
Keywords: DAA; Direct Acting Antiviral; DCV; Daclatasvir; ETR; End of Treatment Response; HCV; Hepatitis C Virus; PegINF-α; Pegylated Interferon-α; RBV; Ribavirin; RVR; Rapid Virological Response; SOF; Sofosbuvir; SVR12; Sustained Virological Response Post-treatm
Evaluation of TRIM5 and TRIM22 polymorphisms on treatment responses in Iranian patients with chronic hepatitis C virus infection
Keywords: HCV; hepatitis C virus; CHC; chronic HCV; HCC; hepatocellular cancer; SVR; sustained virologic response; TRIM; tripartite motif; pegIFN-α/RBV; pegylated interferon-α and ribavirin; DDAs; direct-acting antivirals; RVR; rapid virologic response; cEVR; com
Efficacy And Safety of Sofosbuvir Based Regimens For Treatment of Hepatitis C Recurrence After Living Donor Liver Transplantation: An Experience From India
Keywords: DAA; direct acting antivirals; DDLT; deceased donor liver transplant; ETR; end of treatment response; HCV; hepatitis C; LDLT; living donor liver transplantation; RVR; rapid virological response; SVR12; sustained virological response at 12 weeks; hepatitis
Impact of Direct Acting Antiviral Therapy for Treatment of Hepatitis C Genotypes 1, 3 and 4: A Real Life Experience from India
Keywords: DAA; Direct Acting Antiviral; DCV; Daclatasvir; EASL; European Association of Study of the Liver (EASL); ETR; End of Treatment Response; HBV; Hepatitis B; HCC; Hepatocellular Carcinoma; HCV; Hepatitis C Virus; HIV; Human Immunedeficiency Virus; ITT; inten
Generic Direct Acting Antivirals in Treatment of Chronic Hepatitis C Infection in Patients of Thalassemia Major
Keywords: PRC; packed red blood cells; HIV; human immunodeficiency virus; DAAs; direct acting antivirals; SVR; sustained virological response; RNA; ribonucleic acid; VAS; visual analogue scale; RVR; rapid virological response; EBR; elbasvir; GZR; grazoprevir; SD; s
Changes in risk behaviours during and following treatment for hepatitis C virus infection among people who inject drugs: The ACTIVATE study
Keywords: HCV; hepatitis C virus; PWID; people who inject drugs; DAAs; directly acting antivirals; OST; opioid substitution therapy; OR; odds ratio; CI; confidence interval; HIV; human immunodeficiency virus; RVR; rapid virological response; RNA; ribonucleic acid;
Effect of IL15 rs10833 and SCARB1 rs10846744 on virologic responses in chronic hepatitis C patients treated with pegylated interferon-α and ribavirin
Keywords: HCV; hepatitis C virus; CHC; chronic HCV; HCC; hepatocellular cancer; SVR; sustained virologic response; SCARBI; scavenger receptor type B class I; IL-15; interleukin-15; DDAs; direct-acting antivirals; RVR; rapid virologic response; cEVR; completely earl
Research ArticleHepatitis C reinfection after sustained virological response
Keywords: HCV; hepatitis C virus; PWID; people who inject drugs; SVR; sustained virological response; IDU; injecting drug use; DAAs; direct-acting antivirals; RNA; ribonucleic acid; OST; opioid substitution treatment; RVR; rapid virological response; E1; envelope 1
IFNL4 ss469415590 polymorphism contributes to treatment decisions in patients with chronic hepatitis C virus genotype 1b, but not 2a, infection
Keywords: ALT; alanine aminotransferase; AST; aspartate aminotransferase; BMI; body mass index; cEVR; complete early virological response; CHC; chronic hepatitis C; CI; confidence interval; ETVR; end-of-treatment virological response; EVR; early virological respons
Optimal retrofit of a CO2 capture pilot plant using superstructure and rate-based models
Keywords: CCS; carbon capture and storage; EOR; enhanced oil recovery; GA; genetic algorithm; IMTP; Intalox metal tower packing; LVR; lean vapor recompression; MEA; monoethanolamine; MVR; mechanical vapor recompression; PCC; post-combustion carbon capture; PZ; pipe
Roles of ITPA and IL28B genotypes in chronic Hepatitis C patients treated with peginterferon plus ribavirin in Tunisian population
Keywords: ITPA; inosine triphosphate; SVR; sustained virological response; HCV; hepatitis C virus; HCC; hepatocellular carcinoma; PEG-IFN; pegylated interferon; GWAS; Genome Wide Association Study; SNPs; single nucleotide polymorphisms; III IFN; interferon III; IL2
Research ArticleDaclatasvir and asunaprevir plus peginterferon alfa and ribavirin in HCV genotype 1 or 4 non-responders
Keywords: HCV; hepatitis C virus; SVR; sustained virological response; LLOQ; lower limit of quantification; DAA; direct-acting antiviral; ALT; alanine aminotransferase; ULN; upper limit of normal; AE; adverse event; RVR; rapid virological response; cEVR; complete e
In vitro combinations containing Tegobuvir are highly efficient in curing cells from HCV replicon and in delaying/preventing the development of drug resistance
Keywords: DAA; direct acting antivirals; SOC; standard of care; Peg_IFN; pegylated interferon; RBV; ribavirin; RVR; rapid virological response; cEVR; complete early virological response; vRVR; very rapid viral response; 2â²-C-MeCyt; 2â²-C-methylcytidine; TCA; thi
Identification of naïve HVC-4 patients who may be treated with pegylated-interferon and ribavirin according to IL28B polymorphisms
Keywords: HCV; hepatitis C virus; HCV-4; hepatitis C virus genotype 4; PEG-IFN; pegylated interferon alfa; SVR; sustained virological response; RVR; rapid virological response; EVR; early virological response; SNP; single nucleotide polymorphism; IL; interleukin; N
Research ArticleExtended duration therapy with pegylated interferon and ribavirin for patients with genotype 3 hepatitis C and advanced fibrosis: Final results from the STEPS trial
Keywords: AE; adverse event; Hb; hemoglobin; HCV; hepatitis C virus; HIV; human immunodeficiency virus; PegIFN/RBV; peginterferon-α and ribavirin; RNA; ribonucleic acid; RVR; rapid virologic response; SAE; serious adverse event; SVR; sustained virologic response;
Comparative Effectiveness of Telaprevir-Based Triple Therapy in Patients With Chronic Hepatitis C
Keywords: HCV; hepatitis C virus; p-IFN; pegylated interferon; RBV; ribavirin; RVR; rapid virologic response; SVR; sustained virologic response;
Hepatocyte expression of TRAIL pathway regulators correlates with histopathological and clinical parameters in chronic HCV infection
Keywords: cFLIP; cellular FLICE/caspase-8-inhibitory protein; cEVR; complete early viral response; CMV; cytomegalovirus; DR; death receptor; EBV; Epstein-Barr virus; EVR; early virologic response; FADD; FAS-associated via death domain; HCC; hepatocellular carcino
Research ArticleA randomized phase 2b study of peginterferon lambda-1a for the treatment of chronic HCV infection
Keywords: Lambda; peginterferon lambda-1a; alfa; peginterferon alfa-2a; GT1,4; HCV genotype 1 or 4; GT2,3; HCV genotype 2 or 3; cEVR; complete early virologic response; RVR; rapid virologic response; EOT; end-of-treatment; SVR12; sustained virologic response at pos
My Treatment Approach to Chronic Hepatitis CÂ Virus
Keywords: BOC; boceprevir; FDA; Food and Drug Administration; HCC; hepatocellular carcinoma; HCV; hepatitis C virus; HIV; human immunodeficiency virus; PEGINF; peginterferon; RBV; ribavirin; RVR; rapid virologic response; SMV; simeprevir; SOF; sofosbuvir; SVR; sust
Combination of Vaniprevir With Peginterferon and Ribavirin Significantly Increases the Rate of SVR in Treatment-Experienced Patients With Chronic HCV Genotype 1 Infection and Cirrhosis
Keywords: Clinical Trial; Fibrosis; Direct-Acting Antiviral Agent; HCV; hepatitis C virus; LLQ; lower limit of quantification; mITT; modified intention-to-treat; P/R; peginterferon alfa and ribavirin; RAV; resistance-associated variants; RVR; rapid virologic respon
Simeprevir Increases Rate of Sustained Virologic Response Among Treatment-Experienced Patients With HCV Genotype-1 Infection: A Phase IIb Trial
Keywords: Direct-Acting Antivirals; DAA; Clinical Trial; SVR24; AE; adverse event; EOT; end of treatment; FSS; Fatigue Severity Scale; HCV; hepatitis C virus; PegIFN; peginterferon-α2a; PegIFN-α; peginterferon-α; RBV; ribavirin; RVR; rapid virologic response; SV
EASL Clinical Practice Guidelines: Management of hepatitis C virus infection
Keywords: AE; adverse event; ALT; alanine aminotransferase; BMI; body mass index; BOC; boceprevir; BT; viral breakthrough; CPGs; Clinical Practice Guidelines; CYP3A4; cytochrome p450 3A4; DAA; direct-acting antiviral; DVR; delayed virological response; EIA; enzyme
Sofosbuvir (GS-7977) plus peginterferon/ribavirin in treatment-naïve patients with HCV genotype 1: A randomized, 28-day, dose-ranging trial
Keywords: HCV; hepatitis C virus; PegIFN; pegylated interferon; RBV; ribavirin; RVR; rapid virologic response; SVR; sustained virologic response; IL; interleukin; LOD; limit of detection; MedDRA; Medical Dictionary for Regulatory Activities; ECG; electrocardiogram;
Research ArticleTemperature rise after peginterferon alfa-2a injection in patients with chronic hepatitis C is associated with virological response and is modulated by IL28B genotype
Keywords: HCV; hepatitis C virus; PegIFN; peginterferon alfa 2a; IP-10; interferon-gamma-inducible protein-10; IFN; interferon; PGE2; prostaglandin E2; ISG; interferon-stimulated gene; RVR; rapid virological response; EVR; early virological response; SVR; sustained
Research ArticleTelaprevir can be successfully and safely used to treat older patients with genotype 1b chronic hepatitis C
Keywords: TVR; telaprevir; RVR; rapid virological response; SVR; sustained virological response; IL28B; interleukin 28B; HCV; hepatitis C virus; HCC; hepatocellular carcinoma; PegIFN-α; pegylated interferon α; RBV; ribavirin; NS3/4A; non-structural 3/4A; DAA; dir
ReviewNS5A inhibitors in the treatment of hepatitis C
Keywords: HCV; hepatitis C virus; DAA; direct acting antiviral; NS; nonstructural; RdRp; RNA-dependent RNA polymerase; IFN; interferon; UTR; untranslated region; IRES; internal ribosome entry site; SVR; sustained virological response; RVR; rapid virologic response;
Research ArticleEffect of gender and ITPA polymorphisms on ribavirin-induced anemia in chronic hepatitis C patients
Keywords: HCV; Hepatitis C virus; SVR; sustained virologic response; RVR; rapid virologic response; SNP; single nucleotide polymorphism; GWAS; genome-wide association study; HCV; Gender; Age; Ribavirin-induced anemia; ITPA;
Research ArticleClinical milestones for the prediction of severe anemia by chronic hepatitis C patients receiving telaprevir-based triple therapy
Keywords: HCV; hepatitis C virus; PegIFN; pegylated interferon; RBV; ribavirin; SVR; sustained virological response; TVR; telaprevir; ITPA; inosine triphosphatase; SNP; single nucleotide polymorphism; Hb; hemoglobin; eGFR; estimated glomerular filtration rate; RVR;
ReviewPerspectives and challenges of interferon-free therapy for chronic hepatitis C
Keywords: HCV; hepatitis C virus; HIV; human immunodeficiency virus; SVR; sustained virologic response; RVR; rapid virologic response; eRVR; extended rapid virologic response; EVR; early virologic response; peg; pegylated; IFN; interferon; IL28B; interleukin 28B; D
Innate Immune Tolerance and the Role of Kupffer Cells in Differential Responses to Interferon Therapy Among Patients With HCV Genotype 1 Infection
Keywords: PBMC; Microarray Analysis; Therapeutic Efficacy; Drug; EVR; early virologic responder; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; IFITM1; interferon-induced transmembrane 1; IFN; interferon; ISG; interferon-stimulated gene; NR; nonresponder; OAS; ol
Virologic response at week 8 of combined treatment as a predictor of sustained virologic response in non rapid virologic response, chronic HCV genotype 4 infected patients
Keywords: Week 8; SVR; RVR; HCV; Genotype 4
Will Interferon-Free Regimens Prevail?
Keywords: CHC; chronic hepatitis C virus infection; DAA; direct-acting antiviral; HTA; host-targeting agent; Peg-IFN; peginterferon; RAV; resistance-associated amino acid variant; RBV; ribavirin; RVR; rapid virologic response; SVR; sustained virologic response;
Research ArticleIL28B polymorphism is associated with treatment response in patients with genotype 4 chronic hepatitis C
Keywords: GWAS; genome wide association study; HCV; hepatitis C virus; IFN-λ3; interferon λ3; IL28B; interleukin 28B; NR; non response; PCR; polymerase chain reaction; PEG-IFN; pegylated interferon; RVR; rapid virological response; SNP; single nucleotide polymorp
Research ArticleHyporesponsiveness to PegIFNα2B plus ribavirin in patients with hepatitis C-related advanced fibrosis
Keywords: HCV; hepatitis C virus; PegIFN; pegylated-interferon; Rbv; ribavirin; Peg; polyethylene glycol; SVR; sustained virological response; RVR; rapid virological response; cEVR; complete early virological response; ETR; end of treatment response; S; Ishak fibro
Research ArticleRefined prediction of week 12 response and SVR based on week 4 response in HCV genotype 1 patients treated with peginterferon alfa-2a (40KD) and ribavirin
Keywords: RVR; rapid virological response; SVR; sustained virological response; HCV; hepatitis C virus; EVR; early virological response; PCR; polymerase chain reaction; cEVR; complete early virological response; Hepatitis C; Peginterferon; Peginterferon alfa-2a; Su
Research ArticleAntiviral activity of TMC435 monotherapy in patients infected with HCV genotypes 2-6: TMC435-C202, a phase IIa, open-label study
Keywords: HCV; hepatitis C virus; PegIFN; peginterferon; RBV; weight-based ribavirin; SVR; sustained virologic response; AE; adverse event; DAA; direct-acting antiviral; q.d.; once daily; RVR; rapid virologic response; IC; inhibitory concentration; ECG; electrocard
Research ArticleInterleukin-28B genetic variants in identification of hepatitis C virus genotype 1 patients responding to 24 weeks peginterferon/ribavirin
Keywords: HCV; hepatitis C virus; CHC; chronic hepatitis C; GWAS; genome-wide associated studies; SNP; single nucleotide polymorphism; IL-28B; interleukin 28B; SVR; sustained virological response; RVR; rapid virological response; EOTVR; end-of-treatment virological
Research ArticleA randomized trial of 48 versus 24 weeks of combination pegylated interferon and ribavirin therapy in genotype 6 chronic hepatitis C
Keywords: HCV; hepatitis C virus; ALT; alanine aminotransferase; AST; aspartate aminotransferase; PEG-IFN; pegylated interferon; RBV; ribavirin; SVR; sustained virological response; RVR; rapid virological response; cEVR; complete early virological response; ETR; en
Research ArticleLack of TGF-β production by hepatitis C virus-specific T cells during HCV acute phase is associated with HCV clearance in HIV coinfection
Keywords: TGF-β; transforming growth factor-beta; HCV; hepatitis C virus; HIV; human immunodeficiency virus; ICS; intracellular cytokine staining; IFN; interferon; SVR; sustained virologic response; RVR; rapid virologic response; PBMC; peripheral blood mononuclear
Rotational velocity rescaling of molecular dynamics trajectories for direct prediction of protein NMR relaxation
Keywords: RVR; rotational velocity rescaling; GB3; B3 domain of Protein G; PDB; protein data bank; MD; molecular dynamics; rms; root mean square; RDC; residual dipolar coupling; NOE; nuclear Overhauser enhancement; CSA; chemical shift anisotropy; ROESY; rotating fr
Experimental investigation of a Kaplan draft tube – Part II: Off-design conditions
Keywords: Kaplan; LDA; Pressure recovery; Phase-averaged; RVR
International HepatologyNS5A inhibitors: A new breakthrough for the treatment of chronic hepatitis C
Keywords: DAAs; direct acting antivirals; SVR; sustained virological response; RVR; rapid virological response; PEG-IFN; pegylated-interferon; RBV; ribavirin; HCC; hepatocellular carcinoma; Boceprevir; Telaprevir; Pegylated interferon; Ribavirin; Protease inhibitor
HBsAg loss with HBsAg/anti-HBs seroconversion and non-detectable HCV-RNA in a patient with chronic HBV e-minus/HCV hepatitis treated with two cycles of antiviral therapy
Keywords: Chronic hepatitis; Coinfection; Hepatitis B Virus (HBV); Hepatitis C Virus (HCV); Peginterferon-alfa; Ribavirin; ALT; (serum) Alanine Transaminase; Anti-HBs (HBsAb); Antibody to Hepatitis B surface (antigen); AST; (serum) Aspartate Transaminase; CH; Chron
International HepatologyA sprint to increase response to HCV treatment: Expectancies but caution
Keywords: DAA; direct acting antivirals; SVR; sustained virological response; RVR; rapid virological response; PEG-IFN; pegylated-interferon; RBV; ribavirin; Boceprevir; Pegylated interferon; Ribavirin; Protease inhibitors; IL28B;
Research ArticleEarly virologic response and IL28B polymorphisms in patients with chronic hepatitis C genotype 3 treated with peginterferon alfa-2a and ribavirin
Keywords: RVR; rapid virological response; UVR; ultrarapid virological response; HCV; hepatitis C virus; BMI; body mass index; SVR; sustained virological response;