Molecular Analysis of Two Novel Missense Mutations in the GDF5 Proregion That Reduce Protein Activity and Are Associated with Brachydactyly Type C
Keywords: GDF5, growth and differentiation factor 5; BMP, bone morphogenetic protein; BDC, brachydactyly type C; FL, full length; rh, recombinant human; SBE, SMAD binding element; PFU, plaque-forming units; DMEM, Dulbecco's modified Eagle's medium; FBS, fetal bovin