
Subtle changes in TCRα CDR1 profoundly increase the sensitivity of CD4 T cells
Keywords: APL; altered peptide ligand; CAb; clonotypic Ab for n3.L2 TCR; DN; double negative thymocytes; DP; double positive thymocytes; Hb; hemoglobin; koff; off-rate constant; kon; on-rate constant; MHCII; MHC class II; pMHC; peptide MHC complex; scTCR; single ch