Abcb1a (P-glycoprotein) limits brain exposure of the anticancer drug candidate seliciclib in vivo in adult mice
Keywords: سلتیکلیب; Seliciclib; Blood-brain barrier; P-glycoproptein; Mice; Microdialysis; BBB; blood brain barrier; ER; efflux ratio; CDK; cyclin-dependent kinase; ABCB1/P-gp/MDR1; ATP-binding Cassette B1/P-glycoprotein/Multidrug Resistance Protein 1; CSF; arteficial cerebr