Keywords: AMPAR; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor; Arc; activity-regulated cytoskeletal-association protein; BDNF; bone-derived neurotrophic factor; CaMK; Ca2+/calmodulin-dependent protein kinase; cAMP; cyclic adenosine monophosphate;
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Ubiquitination/sumoylation: An alternative pathway to modify gene regulation directed by xenosensors
Keywords: Epigenetic regulation; Post-translational modifications; Nuclear receptors; Xenobiotics metabolism; AHR; aryl hydrocarbon receptor; AHRR; aryl hydrocarbon receptor repressor; ARNT; aryl hydrocarbon receptor nuclear translocator; CAR; constitutive androsta
Novel signal transducer and activator of transcription 1 mutation disrupts small ubiquitin-related modifier conjugation causing gain of function
Keywords: Signal transducer and activator of transcription 1; gain of function; sumoylation; small ubiquitin-related modifier; IFN-γ; Rhodococcus species infection; CMC; Chronic mucocutaneous candidiasis; GFP; Green fluorescent protein; GOF; Gain of function; IP10
Mechanisms of the amplifying pathway of insulin secretion in the β cell
Keywords: ABCC8; ATP binding cassette subfamily C member 8; ADCY5; adenylyl cyclase type 5; AICAR; 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside; DPP-IV; dipeptidyl peptidase 4; G6PD; glucose-6-phosphate dehydrogenase; GDH; glutamate dehydrogenase; GIP; gast
Sub-cellular localization specific SUMOylation in the heart
Keywords: AMPK; adenosine monophosphate-activated protein kinase; CAMKK; calcium-calmodulin-activated protein kinase kinase; CHIP; carboxyl terminus of HSP70-interacting protein; CVD; cardiovascular disease; cTnI; cardiac troponin I; d-flow; disturbed flow; DeSI; d
Vialinin A and thelephantin G, potent inhibitors of tumor necrosis factor-α production, inhibit sentrin/SUMO-specific protease 1 enzymatic activity
Keywords: cSENP1; catalytic human SUMO-specific protease; DUB; deubiquitinating enzyme; IC50; half maximal inhibitory concentration; rhSENP1; recombinant human SUMO-specific protease; SENP; SUMO-specific protease; SUMO; small ubiquitin-related protein modifier; SUM
Development and evaluation of a highly reliable assay for SUMO-specific protease inhibitors
Keywords: SUMO; SENP; DeSUMOlyation; Inhibitor; Assay;
Evaluation of the activity and substrate specificity of the human SENP family of SUMO proteases
Keywords: RRL; rabbit reticulocyte lysate; SENP; sentrin/SUMO-specific protease; SIM; SUMO-interacting motif; SUMO; small ubiquitin-like modifier; VME; vinyl methyl ester; VS; vinyl sulfone; Sentrin/SUMO-specific proteases; SENPs; SUMO; SUMO precursors; RanGAP1; Po
Advances in the development of SUMO specific protease (SENP) inhibitors
Keywords: Sumoylation; SUMO; SENP; Prostate cancer; Virtual screening
Quantitative Förster resonance energy transfer analysis for kinetic determinations of SUMO-specific protease
Keywords: Förster resonance energy transfer (FRET); Quantitative FRET analysis; SENP; Kinetic determinations;
SUMOylation of Blimp-1 promotes its proteasomal degradation
Keywords: Blimp-1; B lymphocyte induced maturation protein-1; KLF; Krueppel-like factor; PC; plasma cells; SENP; SUMO-specific protease; SUMO; small ubiquitin-like modifier; Plasma cell; SENP1; SUMO protease; Proteasome;
SUMOylation and de-SUMOylation in response to DNA damage
Keywords: SUMO; SENP; RPA; Repair; Replication;
Thiol-protease oxidation in age-related neuropathology
Keywords: AD; Alzheimer disease; Atg; autophagin; IDE; insulysin; MJD; Machado-Joseph disease; MMP; matrix metalloproteinase; NEP; neprilysin; PD; Parkinson disease; SENP; sentrin-specific protease; SUMO; small-ubiquitin modifier; TIMP-1; tissue inhibitor of meta
The mouse small ubiquitin-like modifier-2 (SUMO-2) inhibits interleukin-12 (IL-12) production in mature dendritic cells by blocking the translocation of the p65 subunit of NFκB into the nucleus
Keywords: B6; C57BL/6; ChIP; chromatin immunoprecipitation; CM; complete medium; DC; dendritic cell; EMSA; electrophoretic mobility shift assay; IL-12; interleukin-12; LPS; lipopolysaccharide; NK cell; natural killer cell; MHC; major histocompatibility complex; SEN
Targets and consequences of protein SUMOylation in neurons
Keywords: SUMO; Ubc9; Ubiquitin; SENP; Post-translational modification; Neuronal function
Emerging roles of desumoylating enzymes
Keywords: Desumoylation enzyme; SUMO; Ulp; SENP; SUMO isoform