Overcoming bioanalytical challenges associated with the separation and quantitation of GSK1278863, a HIF-prolyl hydroxylase inhibitor, and its 14 stereoisomeric metabolites
Keywords: HLQ, higher limit of quantification; LLQ, lower limit of quantification; UHPLC–MS/MS, ultra high performance liquid chromatography tandem mass spectrometry; SFC, supercritical fluid chromatography; UPC2, ultra performance convergence chromatography; SPE,