دانلود مقالات ISI درباره SH2، Src همولوژی 2 + ترجمه فارسی

ایزومیزاسیون پرولیل و کاتالیزور آن در تجمع پروتئین و پروتئین

Prolyl Isomerization and Its Catalysis in Protein Folding and Protein Function

Keywords: SH2، Src همولوژی 2; RNase A, ribonuclease A; Itk, interleukin-2 tyrosine kinase; SH2, Src homology 2; G3P, gene 3 protein; EF-G, elongation factor G; CypA, cyclophilin A; FKBP, FK506 binding protein; TF, trigger factorprotein folding; protein regulation; prolyl isomerases; c

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2015 سفارش ترجمه

Identification of a truncated kinase suppressor of Ras 2 mRNA in sperm

Keywords: SH2، Src همولوژی 2; KSR, kinase suppressor of Ras; ERK, extracellular signal-regulated protein kinase; T-KSR2, testes-kinase suppressor of Ras 2; MAPK, mitogen activated protein kinase; CA, conserved area; SH2, Src homology 2; RACE, rapid amplification of cDNA ends; NDK-1, n

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Phylogenetic analysis, expression patterns, and transcriptional regulation of human CTEN gene

Keywords: SH2، Src همولوژی 2; Cten, C-terminal tensin-like; SH2, Src homology 2; PTB, phosphotyrosine-binding; Q-PCR, quantitative-PCR; 5′RAC, 5′-Rapid amplification of cDNA ends; CDS, coding regions; MSA, multiple sequence alignment (MSA); BPH, benign prostatic hyperplasia (BPH); ENC

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Genetic Incorporation of a Photo-Crosslinkable Amino Acid Reveals Novel Protein Complexes with GRB2 in Mammalian Cells

Keywords: SH2، Src همولوژی 2; SH2, Src homology 2; pBpa, p-benzoyl-l-phenylalanine; EGFR, epidermal growth factor receptor; SH3, Src homology 3; pTyr, phosphorylated tyrosine; EGF, epidermal growth factor; tmdPhe, p-trifluoromethyl-diazirinyl-l-phenylalanine; TyrRS, tyrosyl-tRNA synth

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Functional Implications of the Conformational Switch in AICD Peptide upon Binding to Grb2-SH2 Domain

Keywords: SH2، Src همولوژی 2; APP, amyloid precursor protein; AICD, APP intracellular C-terminal domain; AD, Alzheimer's disease; SH2, Src homology 2; Grb2, growth factor receptor binding protein-2; PTB, protein tyrosine binding; PDB, Protein Data Bank; CFP, cyan fluorescent protein;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

Mutation of tyrosine residue 857 in the PDGF β-receptor affects cell proliferation but not migration

Keywords: SH2، Src همولوژی 2; PDGF, platelet-derived growth factor; PDGFR, PDGF receptor; Erk, extracellular regulated kinase; PAE, porcine aortic endothelial cell; PI3K, phosphatidylinositol 3-kinase; FBS, fetal bovine serum; SH2, Src homology 2; SHP-2, SH2-domain containing phosphat

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

What precedes the initial tyrosine phosphorylation of the high affinity IgE receptor in antigen-activated mast cell?

Keywords: SH2، Src همولوژی 2; FcεRI, high-affinity IgE receptor; MIRR, multichain immune recognition receptor; ITAM, immunoreceptor tyrosine-based activation motif; SH2, Src homology 2; PTK, protein tyrosine kinase; PTP, protein tyrosine phosphatase; RBL, rat basophilic leukemia; EGFP

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Identification of an Allosteric Signaling Network within Tec Family Kinases

Keywords: SH2، Src همولوژی 2; Itk, interleukin-2 tyrosine kinase; Btk, Bruton's tyrosine kinase; SH2, Src homology 2; SH3, Src homology 3; PKA, protein kinase A; PDB, Protein Data BankItk and Btk; regulatory spine; kinase activation; gatekeeper residue; phosphorylation

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Activated Rac1 requires gp130 for Stat3 activation, cell proliferation and migration

Keywords: SH2، Src همولوژی 2; STATs, Signal Transducers and Activators of Transcription; IL6, Interleukin-6; ptyr, phosphorylated tyrosine; Erk, Extracellular-signal activated kinase; SH2, Src homology 2; JAKs, Janus kinases; Hsp90, Heat shock protein 90; NFkB, Nuclear Factor-kappaB;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

Functional Interaction of the Ras Effector RASSF5 with the Tyrosine Kinase Lck: Critical Role in Nucleocytoplasmic Transport and Cell Cycle Regulation

Keywords: SH2، Src همولوژی 2; NES, nuclear export signal; SH3, Src homology 3; NLS, nuclear localization signal; LMB, leptomycin B; SH2, Src homology 2; NPC, nuclear pore complex; CHX, cycloheximide; GFP, green fluorescent protein; GST, glutathione S-transferase; DMEM, Dulbecco's modi

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2010 سفارش ترجمه

Csk-binding protein can regulate Lyn signals controlling cell morphology

Keywords: SH2، Src همولوژی 2; Csk, COOH-terminal Src kinase; Cbp, Csk binding protein; SH2, Src homology 2; SH3, Src homology 3; Epo, erythropoietin; SOCS1, suppressor of cytokine signaling 1; STAT, signal transducer and activator of transcription; JAK, Janus kinase; PLCγ, phspholipas

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2009 سفارش ترجمه

SH2-Dependent Autophosphorylation within the Tec Family Kinase Itk

Keywords: SH2، Src همولوژی 2; Itk, interleukin-2 tyrosine kinase; Btk, Bruton's tyrosine kinase; SH2, Src homology 2; SH3, Src homology 3; XLA, X-linked agammaglobulinemia; Csk, C-terminal Src kinase; Irk, insulin receptor kinase; PI3K, phosphoinositide 3-kinase; HSQC, heteronuclear s

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2009 سفارش ترجمه

Proline Isomerization Preorganizes the Itk SH2 Domain for Binding to the Itk SH3 Domain

Keywords: SH2، Src همولوژی 2; Itk, interleukin-2 tyrosine kinase; SH3, Src homology 3; SH2, Src homology 2; PH, Pleckstrin homology; pY, phosphotyrosine; RDC, residual dipolar coupling; NOE, nuclear Overhauser enhancement; NOESY, NOE spectroscopy; 3D, three-dimensional; TOCSY, total c

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2009 سفارش ترجمه

Tyk2 expression and its signaling enhances the invasiveness of prostate cancer cells

Keywords: SH2، Src همولوژی 2; Jak, Janus kinase; RT-PCR, reverse transcriptase-polymerase chain reaction; SH2, Src homology 2; Stat, signal transducers and activators of transcriptionTyk2; Jak; Prostate cancer; Invasion; Metastasis

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

The nuclear localization of SOCS6 requires the N-terminal region and negatively regulates Stat3 protein levels

Keywords: SH2، Src همولوژی 2; SOCS, suppressors of cytokine signaling; STAT, signal transducer and activator of transcription; JAK, Janus kinase; SH2, Src homology 2; CIS, cytokine-inducible SH2-containing protein; IR, insulin receptor; IRS, insulin receptor substrate; GFP, green fluo

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Increased SOCS6 stability with PMA requires its N-terminal region and the Erk pathway via Pkcδ activation

Keywords: SH2، Src همولوژی 2; PMA, phorbol 12-myristate 13-acetate; SOCS, suppressors of cytokine signaling; STAT, signal transducer and activator of transcription; JAK, Janus kinase; SH2, Src homology 2; CIS, cytokine-inducible SH2-containing protein; PKC, protein kinase CPMA; SOCS6;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

High resolution crystal structures of the p120 RasGAP SH3 domain

Keywords: SH2، Src همولوژی 2; SH3, Src homology 3; SH2, Src homology 2; RasGAP, Ras GTPase activating protein; G3BP, RasGAP SH3 binding protein; p190, Rho GTPase activating protein; PH, pleckstrin homology; SAD, Single-wavelength anomalous diffractionRasGAP; SH3 domain; Dimerization;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

Localized activation of Src-family protein kinases in the mouse egg

Keywords: SH2، Src همولوژی 2; MII, meiosis II; GST, glutathione S transferase; SH2, Src homology 2; eCG, equine chorionic gonadotropin; hCG, human chorionic gonadotropin; KSOM, potassium simplex optimized medium; PIPES, piperazine-N,N′-bis[2-ethanesulfonic acid]; EGTA, ethylene glycol

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2007 سفارش ترجمه

Crystal structure of the C-terminal SH3 domain of the adaptor protein GADS in complex with SLP-76 motif peptide reveals a unique SH3–SH3 interaction

Keywords: SH2، Src همولوژی 2; SH3, Src homology 3; SH2, Src homology 2; LAT, linker for activation of T cell; r.m.s.d., root-mean-square difference; PRS, prolin-rich sequencesGADS; SLP-76; SH3; SH3–SH3 interaction; Signaling transduction; X-ray crystallography

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2007 سفارش ترجمه

Solution Structure of a Hck SH3 Domain Ligand Complex Reveals Novel Interaction Modes

Keywords: SH2، Src همولوژی 2; Hck, hematopoietic cell kinase; SH3, Src homology 3; SH2, Src homology 2; HckSH3, Hck SH3 domain; Fyn, Fgr/Yes-related kinase; Abl, Abelson tyrosine kinase; Src, Rous sarcoma viral oncogene homolog; Nef, negative factor; ADAM, a disintegrin and metallopro

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2007 سفارش ترجمه

Two dimensional Blue Native-/SDS-PAGE analysis of SLP family adaptor protein complexes

Keywords: SH2، Src همولوژی 2; BCR, B cell antigen receptor; BN-PAGE, Blue Native polyacrylamide gel electrophoresis; 2D, two dimensional; Gads, Grb2-like adaptor protein downstream of Shc; MPC, multiprotein complex; SH2, Src homology 2; SH3, src homology 3; SLP, SH2 domain containing

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Determinants governing the potency of STAT3 activation via the individual STAT3-recruiting motifs of gp130

Keywords: SH2، Src همولوژی 2; aa, amino acid; ELISA, enzyme-linked immunosorbant assay; FERM, four-point-one, ezrin, radixin, moesin; JAK, Janus kinase; R, receptor; SH2, Src homology 2; SHP2, SH2-domain-containing tyrosine phosphatase 2; SOCS, suppressor of cytokine signalling; STAT,

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Regulation of Stat3 nuclear import by importin α5 and importin α7 via two different functional sequence elements

Keywords: SH2، Src همولوژی 2; STAT, Signal Transducers and Activators of Transcription; IP, immunoprecipitation; JAK, Janus kinase; SH2, Src homology 2; PCR, polymerase chain reaction; PBS, phosphate-buffered saline; TCL, total cell lysate; GST, Glutathione-S-transferase; SDS-PAGE, SD

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه