The tyrosine phosphatase, SHP-1, is involved in bronchial mucin production during oxidative stress
Keywords: SHP-1; Oxidative stress; Mucin; Asthma;
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SHP-1, a novel peptide isolated from seahorse inhibits collagen release through the suppression of collagenases 1 and 3, nitric oxide products regulated by NF-κB/p38 kinase
Keywords: SHP-1; Collagen; Arthritis; MMP-1; MMP-13; NO; NF-κB/p38 kinase;
IL-10 suppresses CD2-mediated T cell activation via SHP-1
Keywords: Suppression; CD4 T cells; SHP-1; IL-10; CD2; Tolerance
Poly(ADP-ribose) polymerase-1 (PARP-1) transcriptionally regulates angiotensin AT2 receptor (AT2R) and AT2R binding protein (ATBP) genes
Keywords: RAS; renin-angiotensin system; AT1R; angiotensin AT1 receptor; AT2R; angiotensin AT2 receptor; PARP-1; poly(ADP-ribose) polymerase-1; SHP-1; SH2 domain-containing phosphatase 1; PLZF; promyelocytic zinc finger protein; ATBP; AT2R binding protein; ATIP;
Development of fetal brain renin-angiotensin system and hypertension programmed in fetal origins
Keywords: ACE; angiotensin converting enzyme; ACTH; adrenocorticotropic hormone; Ang; angiotensin; AP; area postrema; AT1R; angiotensin II receptor subtype 1; AT2R; angiotensin II receptor subtype 2; ATIP; AT2R-interacting protein; AVP; arginine vasopressin; BBB; b
Purification and Characterization of the Catalytic Domain of Protein Tyrosine Phosphatase SHP-1 and the Preparation of Anti-ÎSHP-1 Antibodies
Keywords: SHP-1; Protein tyrosine phosphatase; Polyclonal antibodies;
TIMP-2 disrupts FGF-2-induced downstream signaling pathways
Keywords: TIMP-2; Angiogenesis; Integrin α3β1; Shp-1; FGF-2;
Changes in the expression and dynamics of SHP-1 and SHP-2 during cerulein-induced acute pancreatitis in rats
Keywords: SHP-1; SHP-2; Acute pancreatitis; Cerulein; SP600125; Rolipram
Somatostatin/somatostatin receptor signalling: Phosphotyrosine phosphatases
Keywords: Somatostatin; Somatostatin receptors; Phosphotyrosine phosphatase; Cell proliferation; Apoptosis; MAP kinase; SHP-1; SHP-2; DEP-1/PTPη
Protein tyrosine phosphatases in osteoclast differentiation, adhesion, and bone resorption
Keywords: Bone; Dephosphorylation; Osteoclast; PTPRO; PTP epsilon; SHP-1; Podosome; PTP-PEST
SiRNA targeting SHP-1 accelerates angiogenesis in a rat model of hindlimb ischemia
Keywords: SHP-1; Protein tyrosine phosphatase; siRNA; Angiogenesis; Hindlimb ischemia; Gene therapy
Identification of leishmania fructose-1,6-bisphosphate aldolase as a novel activator of host macrophage Src homology 2 domain containing protein tyrosine phosphatase SHP-1
Keywords: SHP-1; Src homology 2-domain containing tyrosine phosphatase; EF-1α; elongation factor-1α; GST; glutathione S-transferase; pNPP; p-nitrophenyl phosphate; IFN-γ; interferon-γ; ITIM; immunoreceptor tyrosine-based inhibitory motif; Leishmania; Aldolase;
IL-10 inhibits CD28 and ICOS costimulations of T cells via src homology 2 domain—containing protein tyrosine phosphatase 1
Keywords: IL-10; T cell; suppression; costimulation; anergy; SHP-1; phosphorylation; tolerance; inhibitionCFSE, Carboxyfluorescein succinimidyl ester; cRPMI, Complete Roswell Park Memorial Institute; DN, Dominant-negative; GALV, Gibbon ape leukemia virus; GFP, Gree
Age-related impairment of GM-CSF-induced signalling in neutrophils: Role of SHP-1 and SOCS proteins
Keywords: Ageing; Neutrophils; GM-CSF; Apoptosis; Respiratory burst; SHP-1; SOCS
Granulocyte macrophage-colony stimulating factor reduces the affinity of SHP-2 for the ITIM of CLECSF6 in neutrophils: A new mechanism of action for SHP-2
Keywords: CLECSF6; DCIR; ITIM; Neutrophil; Phosphatase; SHP-1; SHP-2; SHIP-1; Inflammation; Signal transduction; Detergent; GM-CSF; Tyrosine phosphorylation; Peptide
SHP-1 inhibits LPS-mediated TNF and iNOS production in murine macrophages
Keywords: Tyrosine; Macrophage; TNF; iNOS; SHP-1; Cytokine; Signal transduction; Phosphatase; Kinase
Normal neutrophil maturation is associated with selective loss of MAP kinase activation by G-CSF
Keywords: G-CSF; granulocyte colony stimulating factor; GM-CSF; granulocyte-macrophage colony stimulating factor]; MAPK; mitogen-activated protein kinase; STAT3; signal transduction activator of transcription-3; SHP-1; src-homology phosphatase-1; Neutrophils; MAP k
The Tyrosine Phosphatase, SHP-1, Is a Negative Regulator of Endothelial Superoxide Formation
Keywords: AS-ODN; antisense oligodesoxynucleotide; HUVEC; human umbilical vein endothelial cells; NAD(P)H; reduced nicotinamide adenine dinucleotide (phosphate); O2·â; superoxide radical; PI3K; phosphatidyl-inositol-3-kinase; PTP; protein tyrosine phosphatase; A
SHP-1 regulates STAT6 phosphorylation and IL-4-mediated function in a cell type-specific manner
Keywords: IL-4 receptor expression; Signaling; Viable motheaten; IL-4R; IL-4 receptor; SHP-1; SH2 domain-containing protein tyrosine phosphatase-1; mev/mev; Viable motheaten mice; STAT6; Signal transducer and activator of transcription; Jak; Janus kinase;
A SHPing tale: Perspectives on the regulation of SHP-1 and SHP-2 tyrosine phosphatases by the C-terminal tail
Keywords: SHP-1; SHP-2; Phosphatase; C-terminus; Phosphorylation;
Electroacupuncture up-regulates natural killer cell activity
Keywords: Electroacupuncture; NK cell; PTP; PTK; SHP-1; VCAM-1;
Differential signalling during B-cell maturation
Keywords: BCR; B-cell antigen receptor; DAG; diacylglycerol; GC; germinal centre; IP3; inositol-1,4,5-trisphosphate; ITAM; immunoreceptor tyrosine-based activation motif; ITIM; immunoreceptor tyrosine-based inhibition motif; MAPK; mitogen activated protein kinase;
Leishmania donovani engages in regulatory interference by targeting macrophage protein tyrosine phosphatase SHP-1
Keywords: Leishmania donovani; Macrophage; SHP-1;
The role of suppressors of cytokine signalling in thymopoiesis and T cell activation
Keywords: SOCS; suppressor of cytokine signalling; CIS; cytokine-induced SH2-containing protein; SH2; src-homology 2; JAK; Janus kinase; STAT; signal transducers and activators of transcription; IL; interleukin; IFN; interferon; SCF; stem cell factor; SP; single po