Keywords: Medea; Mad; Smox; Insect metamorphosis; Blattella; Smads; Bursicon;
مقالات ISI (ترجمه نشده)
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Keywords: Pancreas; TGF-β; Smads; Embryonic;
TGFβ, smooth muscle cells and coronary artery disease: a review
Keywords: Transforming growth factor-beta; Smads; Cardiovascular disease; Smooth muscle cells; Vascular cells; Revascularisation surgery;
G protein coupled receptors can transduce signals through carboxy terminal and linker region phosphorylation of Smad transcription factors
Keywords: Transactivation; Smads; TGF-β; G protein coupled receptor; Phosphorylation;
Transforming growth factor-β signalling: Role and consequences of Smad linker region phosphorylation
Keywords: Transforming growth factor-β; Smads; Phosphorylation; Cell signalling; Serine/threonine kinases;
Buyanghuanwu Decoction alleviated pressure overload induced cardiac remodeling by suppressing Tgf-β/Smads and MAPKs signaling activated fibrosis
Keywords: Buyanghuanwu Decoction; Cardiac remodeling; Fibrosis; Transformation growth factor-β; Smads; Mitogen-activated protein kinases;
Haplodeficiency of activin receptor-like kinase 4 alleviates myocardial infarction-induced cardiac fibrosis and preserves cardiac function
Keywords: Activin receptor-like kinase 4; Myocardial infarction; Cardiac fibrosis; Smads; MAPK;
TGF-β1 accelerates the DNA damage response in epithelial cells via Smad signaling
Keywords: TGF-β1; DNA damage response; Smads; Lig4; Radioprotection;
Transforming growth factor-β1 SMAD effectors and medial cell number in ascending aorta diseases
Keywords: Aorta; Aneurysms; Immunoperoxidase; Extracellular matrix; TGF-β; SMADs;
Glyoxalase I drives epithelial-to-mesenchymal transition via argpyrimidine-modified Hsp70, miR-21 and SMAD signalling in human bronchial cells BEAS-2B chronically exposed to crystalline silica Min-U-Sil 5: Transformation into a neoplastic-like phenotype
Keywords: Glo1; Glyoxalase I; MG; Methylglyoxal; AGEs; Advanced glycation end products; AP; Argpyrimidine; MS5; Min-U-Sil 5; EMT; Epithelial to mesenchymal transition; E-cad; E-cadherin; ZO-1; Zonula occludens-1; α-SMA; α-smooth muscle actin; ROS; Reactive Oxygen
Hippo circuitry and the redox modulation of hippo components in cancer cell fate decisions
Keywords: Akt/PKB; protein kinase B; AMOT; gene encoding angiomotin; AREG; amphiregulin; BIRC; baculoviral IAP repeat containing protein; βTRCP; beta-transducin repeat containing protein; CD95; cluster of differentiation 95; CDK1; cyclin-dependent kinase 1; CK1δ/
XL413, a cell division cycle 7 kinase inhibitor enhanced the anti-fibrotic effect of pirfenidone on TGF-β1-stimulated C3H10T1/2 cells via Smad2/4
Keywords: Pirfenidone; Cell division cycle 7; Smads; Proliferation; Differentiation
Redox control of p53 in the transcriptional regulation of TGF-β1 target genes through SMAD cooperativity
Keywords: TGF-β1; transforming growth factor-β1; PAI-1; plasminogen activator inhibitor-1; ROS; reactive oxygen species; MEFs; mouse embryo fibroblasts; HPTEC; human proximal tubular epithelial cells; DMEM; Dulbecco's modified Eagle's Medium; DPI; diphenyleneiodo
ALK1 heterozygosity increases extracellular matrix protein expression, proliferation and migration in fibroblasts
Keywords: ALK1; Fibrosis; Extracellular matrix; Smads; Proliferation; Migration;
TGFβ/Smad signalling in psoriatic epidermis models exposed to salt water soaks and narrowband ultraviolet B radiation
Keywords: Transforming growth factor; Smads; Salt water baths; Balneotherapy; Balneophototherapy;
TGF-β signaling in tissue fibrosis: Redox controls, target genes and therapeutic opportunities
Keywords: TGF-β; NOX; NADPH oxidases; PAI-1; ROS; p53; EGFR; SMADs;
Fibroblast growth factor 2 inhibits bone morphogenetic protein 9-induced osteogenic differentiation of mesenchymal stem cells by repressing Smads signaling and subsequently reducing Smads dependent up-regulation of ALK1 and ALK2
Keywords: Fibroblast growth factor 2; Bone morphogenic proteins 9; Osteogenic differentiation; Mesenchymal stem cells; Smads;
Novel WWP2 ubiquitin ligase isoforms as potential prognostic markers and molecular targets in cancer
Keywords: TGFβ; Smads; Ubiquitin ligase; Transcription; Cancer; EMT;
Distinct roles of Smads and microRNAs in TGF-β signaling during kidney diseases
Keywords: chronic kidney disease; microRNAs; Smads; transforming growth factor-β signaling
Thalidomide inhibits fibronectin production in TGF-β1-treated normal and keloid fibroblasts via inhibition of the p38/Smad3 pathway
Keywords: Thalidomide; Keloid; Fibronectin; Mitogen-activated protein kinases (MAPKs); Fibroblasts; SMADS
The ALK-1/Smad1 pathway in cardiovascular physiopathology. A new target for therapy?
Keywords: Angiogenesis; Arteriovenous malformation; HHT; Pulmonary hypertension; Smads; TGF-β
The role of IL-7 in renal proximal tubule epithelial cells fibrosis
Keywords: High glucose; IL-7; Renal fibrosis; Smads; EMT
Preventive effects of rutin on the development of experimental diabetic nephropathy in rats
Keywords: Rutin; Diabetic nephropathy; CTGF; Smads; TGF-β1; Oxidative stress;
Wound healing genes and susceptibility to cutaneous leishmaniasis in Brazil
Keywords: Leishmaniasis; Wound healing; TGFB pathway; CTGF; SMADs; FLII;
BMP receptor-activated Smads confer diverse functions during the development of the dorsal spinal cord
Keywords: Bone morphogenetic proteins; BMPs; BMP signaling; Smads; Receptor-activated Smads; Smad1; Smad5; Spinal cord; Dorsal spinal cord; Neurons; Neural progenitors; Interneurons; Commissural axons; Axon guidance; Axon outgrowth; Cell fate
Metastatic bone disease: Role of transcription factors and future targets
Keywords: Runx/AML/Cbfa1 factors; Runx2; MicroRNA; Breast and prostate tumors in bone; Osteolytic disease; Subnuclear targeting; Smads
In vitro suppression of quercetin on hypertrophy and extracellular matrix accumulation in rat glomerular mesangial cells cultured by high glucose
Keywords: Quercetin; TGF-β1; Smads; Cell cycles; Laminin and type IV collagen; Oxidative stress
Early phase TGFβ receptor signalling dynamics stabilised by the deubiquitinase UCH37 promotes cell migratory responses
Keywords: Smads; TGFβ; Deubiquitinases; Ubiquitination; Transcription; Signalling
Controlling of bone morphogenetic protein signaling
Keywords: Bone morphogenetic protein; Signal transduction; Signaling pathway; Regulation; Smads
Albumin activates the canonical TGF receptor–smad signaling pathway but this is not required for activation of astrocytes
Keywords: Albumin; Astrocyte; Cytokines; TGFβ receptor; Smads
Pentoxifylline Attenuates Transforming Growth Factor-β1-Stimulated Elastogenesis in Human Tunica Albuginea-Derived Fibroblasts Part 2: Interference in a TGF-β1/Smad-Dependent Mechanism and Downregulation of AAT1
Keywords: Smads; Tunica Albuginea; Peyronie's Disease; Pentoxifylline; Elastin; Alpha Antitrypsin;
TGF-beta signaling in chondrocyte terminal differentiation and osteoarthritis: Modulation and integration of signaling pathways through receptor-Smads
Keywords: TGF-beta; Smads; Chondrocytes; Runx2; Osteoarthritis
Modeling and analysis of MH1 domain of Smads and their interaction with promoter DNA sequence motif
Keywords: TGF-β superfamily; Smads; Homology modeling; DNA–Smad interaction
The type I BMP receptors, Bmpr1a and Acvr1, activate multiple signaling pathways to regulate lens formation
Keywords: Lens formation; Bone morphogenetic proteins; Smads;
Insulin gene is a target in activin receptor-like kinase 7 signaling pathway in pancreatic β-cells
Keywords: ALK7; Smads; Insulin promoter; PDX-1; Pancreatic β-cell
Transforming growth factor β suppresses β-catenin/Wnt signaling and stimulates an adhesion response in human colon carcinoma cells in a Smad4/DPC4 independent manner
Keywords: TGFβ, transforming growth factor βTGFβ; Smads; β-Catenin; TCF4; Colon cancer
In vivo effects of TGFβ1 on the growth of gastric epithelium in suckling rats
Keywords: TGFβ1; Smads; p27; Cell proliferation; Apoptosis; Stomach;
Smad2 functions as a co-activator of canonical Wnt/β-catenin signaling pathway independent of Smad4 through histone acetyltransferase activity of p300
Keywords: Alk; activin-like kinase; EV; empty vector; EMT; epithelial-mesenchymal transition; GST; glutathione S transferase; HAT; histone acetyltransferase; SBE; Smad-binding element; TBE; Tcf/Lef-binding element; Activin; Beta-catenin; Smads; Tcf/Lef; TGF-beta;
Mechanisms of TGFβ inhibition of LUNG endodermal morphogenesis: The role of TβRII, Smads, Nkx2.1 and Pten
Keywords: Lung morphogenesis; Branching morphogenesis; TGFβ; TβRII; Smads; NKX2.1; SpC; Pten; Endoderm
Molecular requirements for induction of CTGF expression by TGF-β1 in primary osteoblasts
Keywords: Osteoblast; CTGF; TGF-β1; SMADs; MAPKs; Src
Bone Morphogenetic Proteins and Smad Expression in Ovine Tendon-Bone Healing
Keywords: Tendon-bone healing; Bone morphogenetic proteins; Smads; Immunohistochemistry; Ovine model
Emodin, an anthraquinone derivative from Rheum officinale Baill, enhances cutaneous wound healing in rats
Keywords: Emodin; Wound healing; Transforming growth factor-β1; Smads
Termination of TGF-β Superfamily Signaling Through SMAD Dephosphorylation—A Functional Genomic View
Keywords: transforming growth factor-β (TGF-β); SMADs; dephosphorylation
Novel dominant negative Smad antagonists to TGFβ signaling
Keywords: Smads; Antagonists; TGFβ; GRK2
Agonists of peroxisome proliferators-activated receptors (PPAR) α, β/δ or γ reduce transforming growth factor (TGF)-β-induced proteoglycans' production in chondrocytes
Keywords: PPAR; TGF-β1; Chondrocytes; Proteoglycans; Smads; ERK1/2; PGE2; Alginate system
SnoN co-repressor binds and represses smad7 gene promoter
Keywords: Smads; TGF-β; Ski; SnoN; Smad7
Homology modeling of the DNA-binding domain of human Smad5: A molecular model for inhibitor design
Keywords: Homology modeling; Smads; Transforming growth factor-beta; Phylogenetic analysis; Inhibitor design
XBP1 forms a regulatory loop with BMP-4 and suppresses mesodermal and neural differentiation in Xenopus embryos
Keywords: X. laevis; Embryogenesis; XBP1; Mesoderm; BMP-4; Smads; Unfolded protein response (UPR)
BMP signaling in skeletal development
Keywords: BMPs; BMP receptors; Smads; Skeleton development; Osteoblast differentiation; Chondrogenesis;
Synergistic activation of the murine gastrin promoter by oncogenic Ras and β-catenin involves SMAD recruitment
Keywords: Gastrin; Gene regulation; Oncogene; Ras; Wnt; SMADs; Colorectal cancer;