PAF53 is essential in mammalian cells: CRISPR/Cas9 fails to eliminate PAF53 expression
Keywords: Ribosomal RNA; Nucleolus; RNA polymerase I; rDNA; PAF53; A49; CRISPR/Cas9; Transcription; rDNA; ribosomal DNA; sgRNA; small guide RNA; CRISPR; clustered regularly interspaced short palindromic repeats; Cas9; CRISPR-associated protein-9 nuclease; Pol I; RN