Keywords: SMase، sphingomyelinase; Ceramide; Sphingomyelin-based liposomes; Three-dimensional cultured skin epidermis modelβ-GCase, β-glucocerebrosidase; CBE, Conduritol B epoxide; GlcCer, Glucosylceramide; SM, Sphingomyelin; SM-L, Sphingomyelin-based liposomes; SMase, Sphingomyelinase
مقالات ISI SMase، sphingomyelinase (ترجمه نشده)
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Exogenous ceramide-1-phosphate (C1P) and phospho-ceramide analogue-1 (PCERA-1) regulate key macrophage activities via distinct receptors
Keywords: SMase، sphingomyelinase; C1P, ceramide 1-phosphate; CERA-1, ceramide analog-1; CERK, ceramide kinase; CRE, cAMP response element; LPA, lysophosphatidic acid; MCP-1, monocyte chemoattractant protein-1; PCERA-1, phospho-ceramide analog-1; SM, sphingomyelin; SMase, sphingomyelinase;
Dynamics of ceramide generation and metabolism in response to fenretinide – Diversity within and among leukemia
Keywords: SMase، sphingomyelinase; 4-HPR, N-(4-hydroxyphenyl)retinamide; ROS, reactive oxygen species; GC, glucosylceramide; SPT, serine palmitoyltransferase; SMase, sphingomyelinase; ALL, acute lymphoblastoid leukemia; AML, acute myelogenous leukemia; CML, chronic myelogenous leukemia; TL
Pathological roles of ceramide and its metabolites in metabolic syndrome and Alzheimer's disease
Keywords: SMase، sphingomyelinase; SM, sphingomyelin; Cer, ceramide; SMS, sphingomyelin synthase; MetS, metabolic syndrome; AD, Alzheimer's disease; Aβ, amyloid-β peptide; SLs, sphingolipids; SPT, serine-palmitoyltransferase; SMase, sphingomyelinase; PM, plasma membrane; CERK, ceramide kin
Recruitment of a phospholipase C/sphingomyelinase into non-lamellar lipid droplets during hydrolysis of lipid bilayers
Keywords: SMase، sphingomyelinase; GUVs, giant unilamellar vesicles; PlcHR2, phospholipase C/sphingomyelinase HR2; NMR, nuclear magnetic resonance; PLCs, phospholipases C; SMase, sphingomyelinase; Cer, ceramide; SM, sphingomyelin; Chol, cholesterol; DAG, diacylglycerol; DOPC, 1,2-dioleoyl-
Long chain ceramides and very long chain ceramides have opposite effects on human breast and colon cancer cell growth
Keywords: SMase، sphingomyelinase; Cer, ceramide; dhCer, dihydroceramide; CerS(s), ceramide synthase(s); DES, dihydroceramide desaturase; GCS, glucosylceramide synthase; KSR, 3-ketosphinganine reductase; SMS, sphingomyelin synthase; SMase, sphingomyelinase; Sph1P, sphingosine-1-phosphate;
Endotoxin activates de novo sphingolipid biosynthesis via nuclear factor kappa B-mediated upregulation of Sptlc2
Keywords: SMase، sphingomyelinase; LPS, lipopolysaccharide; SPT, serine palmitoyltransferase; NFκB, nuclear factor kappa B; ChIP, chromatin immunoprecipitation; SM, sphingomyelin; SMase, sphingomyelinase; CAD, coronary artery disease; JNK, c-Jun amino-terminal kinase; dn, dominant negative
The action of sphingomyelinase in lipid monolayers as revealed by microscopic image analysis
Keywords: SMase، sphingomyelinase; SMase, Sphingomyelinase; PLA2, phospholipase A2; Cer, N-acylsphingosine; SM, sphingomyelin; chol, cholesterol; GUVs, giant unilamellar vesicles; ROIs, Regions of Interest; hgd, Highest Gap Distance; GGVF, generalized gradient vector flow; LE, liquid-expan
De novo ceramide synthesis is responsible for the anti-tumor properties of camptothecin and doxorubicin in follicular thyroid carcinoma
Keywords: SMase، sphingomyelinase; CPT, camptothecin; DOX, doxorubicin; FB1, fumonisin B1; FTC, follicular thyroid carcinoma; GCS, glucosylceramide synthase; LASS, longevity assurance homolog; PDMP, phenyl-2-decanoylamino-3-morpholino-1-propanol; SMase, sphingomyelinase; TSP-1, thrombospon
A possible mechanism underlying the ceramide deficiency in atopic dermatitis: Expression of a deacylase enzyme that cleaves the N-acyl linkage of sphingomyelin and glucosylceramide
Keywords: SMase، sphingomyelinase; AD, atopic dermatitis; CDase, ceramidase; GlcCDaseβ, -glucocerebrosidase; GCer, glucosylceramide; GC, glucosylceramide; GSP, glucosylsphingosine; IEF, isoelectric focusing; PC, phosphorylcholine; SM, sphingomyelin; SMase, sphingomyelinase; SS, sphingosine
Transcriptional regulation of neutral sphingomyelinase 2 gene expression of a human breast cancer cell line, MCF-7, induced by the anti-cancer drug, daunorubicin
Keywords: SMase، sphingomyelinase; SMase, sphingomyelinase; SM, sphingomyelin; EMSA, electrophoresis mobility shift assay; ChIP, chromatin immunoprecipitation; DA, daunorubicin; Sp, specificity proteinNSMase2; Daunorubicin; Ceramide; Promoter analysis; EMSA; ChIP; Sp family protein
Specific, rapid, and sensitive enzymatic measurement of sphingomyelin, phosphatidylcholine and lysophosphatidylcholine in serum and lipid extracts
Keywords: SMase، sphingomyelinase; PL, phospholipids; DAOS, N-ethyl-N-(2-hydroxy-3-sulfopropyl)-3,5-dimethoxyaniline; PC, phosphatidylcholine; SM, sphingomyelin; SMase, sphingomyelinase; VLDL, very low-density lipoprotein; LDL, low-density lipoprotein; HDL, high density lipoprotein; PLD, p
Serine palmitoyltransferase inhibitor myriocin induces the regression of atherosclerotic plaques in hyperlipidemic ApoE-deficient mice
Keywords: SMase، sphingomyelinase; SM, sphingomyelin; SMase, sphingomyelinase; SPT, serine palmitoyltransferase; TG, triglyceride; myr, myriocin; PC, phosphatidylcholine; apoE KO, apolipoprotein E deficient; RT-PCR, real-time PCR; SAA, serum amyloid A; SREBP, sterol response element bindin
Sphingomyelinase generation of ceramide promotes clustering of nanoscale domains in supported bilayer membranes
Keywords: SMase، sphingomyelinase; AFM, atomic force microscopy; chol, cholesterol; DOPC, 1,2-dioleoyl-sn-glycero-3-phosphocholine; DPPC, 1,2-dipalmitoyl-sn-glycero-3-phosphocholine; ESM, egg sphingomyelin; GUV, giant unilamellar vesicles; PC, phosphatidylcholine; SMase, sphingomyelinase;
Functions of sphingolipid metabolism in mammals — Lessons from genetic defects
Keywords: SMase، sphingomyelinase; GalCer, galactosylceramide; GlcCer, glucosylceramide; GSL, glycosphingolipid; iNKT cells, invariant natural killer T cells; LacCer, lactosylceramide; S1P, sphingosine 1-phosphate; SL, sphingolipid; SM, sphingomyelin; SMase, sphingomyelinase; SPC, sphingos
Penta-acetyl geniposide-induced apoptosis involving transcription of NGF/p75 via MAPK-mediated AP-1 activation in C6 glioma cells
Keywords: SMase، sphingomyelinase; (Ac)5GP, penta-acetyl geniposide; SMase, sphingomyelinase; NGF, nerve growth factor; MAPK, mitogen-activated protein kinase; ERK, extracellular signal-regulated protein kinase; JNK, c-Jun NH2-terminal kinase; RT-PCR, reverse transcription polymerase chain
Phospholipase D protects ECV304 cells against TNFα-induced apoptosis
Keywords: SMase، sphingomyelinase; Cer, ceramide; TNFα, Tumor necrosis factor α; PLD, phospholipase D; PA, phosphatidic acid; DGK, diacylglycerol kinase; DAG, diacylglycerol; SMase, sphingomyelinase; PBS, phosphate-buffered salinePhospholipase D; siRNA; Tumor necrosis factor α; Ceramide; A
Sphingomyelinase-to-LDL molar ratio determines low density lipoprotein aggregation size: biological significance
Keywords: SMase، sphingomyelinase; LDL, low density lipoprotein; SMase, sphingomyelinase; DLS, dynamic light scattering; SM, egg sphingomyelin; CER, ceramide; n, aggregate number; F, forward rate constant; R, reverse rate constant; PLC, phospholipase CSphingomyelinase; LDL; Aggregation; Dy
Epidermal sphingolipids: Metabolism, function, and roles in skin disorders
Keywords: SMase، sphingomyelinase; Cer, ceramide; CLE, corneocyte lipid envelope (covalently-bound omega-hydroxy ceramides); FA, fatty acid; GlcCer, glucosylceramide; GlcCerase, β-glucocerebrosidase; SC, stratum corneum; SM, sphingomyelin; SMase, sphingomyelinase; N, non-hydroxy fatty acid
Sphingolipids as modulators of cancer cell death: Potential therapeutic targets
Keywords: SMase، sphingomyelinase; GalCer, galactosylceramide; GlcCer, glucosylceramide; GCS, glucosylceramide synthase; MDR, multidrug resistance; ROS, reactive oxygen species; SL, sphingolipid; SM, sphingomyelin; SMase, sphingomyelinase; SMS, sphingomyelin synthase; S1P, sphingosine 1-ph