Hsp105 reduces the protein aggregation and cytotoxicity by expanded-polyglutamine proteins through the induction of Hsp70
Keywords: polyQ; polyglutamine; SMBA; spinal and bulbar muscular atrophy; NLS; nuclear localization signal; NES; nuclear export sequences; JNK; c-Jun N-terminal kinase; p38MAPK; p38 mitogen-activated protein kinase; Hsp105α; Hsp105β; Hsp70; Polyglutamine diseases