Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; SNP, single-nucleotide polymorphism; T2DM, type 2 diabetes mellitus; NPPA, natriuretic peptide precursor A; NPPB, natriuretic peptide precursor B; OR, odds ratio; CI, confidence interval; BMI, body mass index; BNP, brain natriuretic peptide; GWAS, genome-
مقالات ISI SNP، پلی مورفیسم تک نوکلئوتیدی (ترجمه نشده)
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Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; GRK4, G protein–coupled receptor kinase 4; SNP, single-nucleotide polymorphism
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; QTL, quantitative trait loci; SNP, single-nucleotide polymorphism; LV, Lake Victoria; LM, Lake Malawi; LT, Lake Tanganyika; LG, linkage group; cM, centimorgan; LOD, log-likelihoodHybrid line; Linkage group; Linkage mapping
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; GABA, γ-aminobutyric acid; MnPO, median preoptic area; NREM, non-rapid eye movement; PEP, pre-ejection period; PSG, polysomnography; REM, rapid eye movement; SNP, single-nucleotide polymorphism; TMN, tuberomammillary nucleus of the posterior hypothalamus;
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; ALS, amyotrophic lateral sclerosis; FALS, familial amyotrophic lateral sclerosis; SALS, sporadic amyotrophic lateral sclerosis; FTD, frontotemporal dementia; GWAS, genome-wide association study; SNP, single-nucleotide polymorphism; NGS, next generation se
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; LCT, lactase; LPH, lactase-phlorizin hydrolase; SNP, single-nucleotide polymorphism; LP, lactase persistent; LNP, lactase non-persistent; PCR, polymerase chain reaction; DMEM, Dulbecco's Modified Eagle's MediumPig; Lactase; SNP; Luciferase reporter gene;
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; CGN, chronic glomerulonephritis; AH, arterial hypertension; BP, blood pressure; SBP, systolic blood pressure; DBP, diastolic blood pressure; GFR, glomerular filtration rate; DNA, deoxyribonucleic acid; SNP, single-nucleotide polymorphism; ACE, angiotensin
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; AD, Alzheimer's disease; IL, Interleukin; SNP, single-nucleotide polymorphism; ApoE, apolipoprotein E; LOAD, late-onset Alzheimer's disease; Aβ, amyloid-β; MMSE, Mini Mental State Examination; OR, odds ratio; CI, confidence interval; HWE, Hardy–Weinberg e
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; GRS, genetic risk score; SNP, single-nucleotide polymorphism; PKDCC, protein kinase domain containing, cytoplasmic; CDKAL1, CDK5-regulatory subunit-associated protein 1-like 1; WNT16, wingless-type MMTV-integration site family member 16; GPATCH1, G-patch
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; CT imaging; idiopathic pulmonary fibrosis; MUC5B; rs35705950; usual interstitial pneumonitisFIP, familial interstitial fibrosis; G, guanine; IPF, idiopathic pulmonary fibrosis; SNP, single-nucleotide polymorphism; T, thymine; UIP, usual interstitial pneum
Association of protein tyrosine phosphatase non receptor type 22 (PTPN22) C1858T gene polymorphism with type 1 diabetes mellitus in Egyptian children cohort
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; PTPN 22, protein tyrosine phosphatase nonreceptor 22 gene; TCR, T-cell receptors; SNP, single-nucleotide polymorphism; DEMPU, Diabetes Endocrine and Metabolism Pediatric Unit; T1DM, type 1 diabetes mellitus; CTLA4, cytotoxic T lymphocyte antigen-4; LYP, l
High-accuracy haplotype imputation using unphased genotype data as the references
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; KGP, 1000 Genomes Project; SNP, single-nucleotide polymorphism; CEU, CEPH, U.S. Utah residents with ancestry from northern and western Europe; HGDP, Human Genome Diversity ProjectImputation; Big data; References
Genetic variations in SEC16B, MC4R, MAP2K5 and KCTD15 were associated with childhood obesity and interacted with dietary behaviors in Chinese school-age population
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; BMI, body mass index; GWAS, genome-wide association study; SNP, single-nucleotide polymorphism; WC, waist circumference; WtHR, waist-to-height ratio; SD, standard deviations; GRS, genetic risk score; FDR, false discovery rate; MI, multiplicative interacti
Use of genome sequencing to assess nucleotide structure variation of Staphylococcus aureus strains cultured in spaceflight on Shenzhou-X, under simulated microgravity and on the ground
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; PCR, polymerase chain reaction; SNP, single-nucleotide polymorphism; SVs, sequence variants; MRSA, methicillin-resistant Staphylococcus aureus; IRs, insert regions; DRs, deletion regionsStaphylococcus aureus; Spaceflight; Genome; High-throughput; SNP
Platelet Count Mediates the Contribution of a Genetic Variant in LRRC 16A to ARDS Risk
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; ALI, acute lung injury; DIC, disseminated intravascular coagulation; MAF, minor allele frequency; MGH, Massachusetts General Hospital; PLT, platelet count; QC, quality control; QTL, quantitative trait locus; SNP, single-nucleotide polymorphism
The effect of metallothionein 2A core promoter region single-nucleotide polymorphism on accumulation of toxic metals in sinonasal inverted papilloma tissues
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; MT2A, metallothionein 2A; SNP, single-nucleotide polymorphism; IP, sinonasal inverted papilloma; NCM, non-cancerous sinonasal mucosa; RFLP, restriction fragment length polymorphism technique; FASS, flame atomic absorption spectrometer systemMetallothionei
Association between 12p13 SNP rs11833579 and ischemic stroke in Asian population: An updated meta-analysis
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; OR, odds ratio; 95% CI, 95% confidence interval; LAA, large artery atherosclerosis; SAO, small-artery occlusion; SNP, single-nucleotide polymorphism; Ninjurin2, nerve injury induced protein 2; HWE, Hardy–Weinberg equilibriumIschemic stroke; Chromosome 12p
Rapid detection of Down's syndrome using quantitative real-time PCR (qPCR) targeting segmental duplications on chromosomes 21 and 11
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; FISH, fluorescence in situ hybridization; qPCR, quantitative real-time PCR; SNP, single-nucleotide polymorphism; MLPA, multiplex ligation-dependent probe amplification; CNV, copy number variation; QF-PCR, quantitative fluorescent polymerase chain reaction
Genetic variation at IL12B, IL23R and IL23A is associated with psoriasis severity, psoriatic arthritis and type 2 diabetes mellitus
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; BMI, body mass index; CVRF, cardiovascular risk factors; DL, dyslipidemia; DM, diabetes mellitus; HT, arterial hypertension; IC, ischemic cardiomyopathy; OR, odds ratio; Ps, psoriasis; PsA, psoriatic arthritis; SNP, single-nucleotide polymorphism; CI, con
Surfactant Protein-D–Encoding Gene Variant Polymorphisms Are Linked to Respiratory Outcome in Premature Infants
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; BPD, Bronchopulmonary dysplasia; CPAP, Continuous positive airway pressure; Met, Methionine; RD, Respiratory distress; RDS, Respiratory distress syndrome; SFTPD, Surfactant protein-D–encoding gene; SNP, Single-nucleotide polymorphism; SP-D, Surfactant pro
De novo MECP2 duplication derived from paternal germ line result in dysmorphism and developmental delay
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; MECP2, methyl CpG binding protein 2; FISH, fluorescence in situ hybridization; SNP, single-nucleotide polymorphism; CGH, comparative genome hybridization; CNVs, copy number variations; FoSTeS, Fork Stalling and Template Switching; IFN-α, interferon alphaX
Association between TLR2, MTR, MTRR, XPC, TP73, TP53 genetic polymorphisms and gastric cancer: A meta-analysis
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; OR, odds ratio; CI, confidence interval; SNP, single-nucleotide polymorphism; GC, gastric cancer
The impact of GGH -401C > T polymorphism on cisplatin-based chemoradiotherapy response and survival in cervical cancer
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; GGH, Gamma Glutamyl Hydrolase; C, cytosine; T, thymine; SNP, single-nucleotide polymorphism; FIGO, International Federation of Gynecology and Obstetrics; Gy, Gray; RECIST, response evaluation criteria in solid tumors; PCR, polymerase chain reaction; A, Ad
Association between IL13 gene polymorphisms and susceptibility to cancer: A meta-analysis
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; IL13, Interleukin-13; SNP, single-nucleotide polymorphism; HWE, Hardy–Weinberg equilibrium; OR, odds ratios; CI, confidence intervalInterleukin-13; Polymorphism; Meta-analysis; Cancer susceptibility
Bilateral Wilms Tumor and Early Presentation in Pediatric Patients Is Associated with the Truncation of the Wilms Tumor 1 Protein
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; DDS, Denys-Drash syndrome; ESRD, End-stage renal disease; HRM, High-resolution melting; PB, Peripheral blood; SDS, Sodium n-dodecyl sulfate; SNP, Single-nucleotide polymorphism; WT, Wilms tumor; WT1, Wilms tumor 1
Associations between polymorphisms in the antiviral TRIM genes and measles vaccine immunity
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; MMR, measles/mumps/rubella; MV, measles virus; CMI, cell-mediated immunity; LD, linkage disequilibrium; SNP, single-nucleotide polymorphism; TRIM, tripartite motif; IQR, interquartile range; FDR, false discovery rate; EM, expectation-maximization; MAF, mi
Structural and phylogenetic comparison of napsin genes: The duplication, loss of function and human-specific pseudogenization of napsin B
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; NAPSA, napsin A; NAPSB, napsin B; SNP, single-nucleotide polymorphism; cDNA, DNA complementary to RNA; bp, base pair(s); PCR, Polymerase Chain Reaction; kb, kilobase(s) or 1000 bp; NJ, Neighbor-Joining; ML, Maximum-Likelihood; KCNC3, potassium voltage gat
No evidence for an association between ABO blood group and overall ischemic stroke or any of the major etiologic subtypes
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; SAHLSIS, Sahlgrenska Academy Study on Ischemic Stroke; TOAST, Trial of Org 10172 in Acute Stroke Treatment; MI, myocardial infarction; CAD, coronary artery disease; GWAS, genome-wide association study; SNP, single-nucleotide polymorphism; RFLP-PCR, restri
Genetic variants in antioxidant genes are associated with sperm DNA damage and risk of male infertility in a Chinese population
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; ROS, reactive oxygen species; GPX1, glutathione peroxidase 1; CAT, catalase; PON1, paraoxonase 1; SOD2, superoxide dismutase 2; NQO1, NAD(P)H dehydrogenase quinone 1; SNP, single-nucleotide polymorphism; 8-OHdG, 8-hydroxydeoxyguanosineOxidative stress; An
Lack of association between TNF-α gene promoter polymorphisms and pancreatitis: A meta-analysis
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; TNF-α, Tumor necrosis factor alpha; AP, Acute pancreatitis; CP, Chronic pancreatitis; SNP, Single-nucleotide polymorphism; OR, Odds ratio; CI, Confidence intervalSingle-nucleotide polymorphism; 308G>A; 238G>A; Susceptibility; Severity
HLA Class I: An unexpected role in integrin β4 signaling in endothelial cells
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; KIR, the killer cell immunoglobulin like receptor; S6K, S6 kinase; S6RP, S6 ribosome protein; EIF4A1, eukaryotic translation initiation factor 4A1; MMP, matrix metalloproteinase; SNP, single-nucleotide polymorphism
Increased Y-chromosome resolution of haplogroup O suggests genetic ties between the Ami aborigines of Taiwan and the Polynesian Islands of Samoa and Tonga
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; STR, short tandem repeat; SNP, single-nucleotide polymorphism; RFLP, restriction fragment length polymorphism; PCR, Polymerase chain reaction; mtDNA, Mitochondrial DNA; YCC, Y-chromosome consortium; AMOVA, Analyses of Molecular Variance; MDS, Multidimensi
Glutathione (GSH) and the GSH synthesis gene Gclm modulate vascular reactivity in mice
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; GSH, glutathione; GPx, glutathione peroxidase; ROS, reactive oxygen species; SNP, single-nucleotide polymorphism; GCLC, glutamate–cysteine ligase catalytic subunit; GCLM, glutamate–cysteine ligase modifier subunit; WT, wild type; NO, nitric oxide; ACh, ac
The impact of co-morbid conditions on family history of venous thromboembolism in Whites and Blacks
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; AF, attributable fraction; BMI, body mass index; CDC, Centers for Disease Control and Prevention; CI, confidence interval; DVT, deep vein thrombosis; OR, odds ratio; PE, pulmonary embolism; SNP, single-nucleotide polymorphism; VTE, venous thromboembolismC
Structural and Functional Impact of Cancer-Related Missense Somatic Mutations
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; SNP, single-nucleotide polymorphism; SVM, support vector machine; GEF, guanine nucleotide exchange factor; GAP, GTPase-activating protein; PDB, Protein Data Bank; HC, high confidence; XDH, xanthine dehydrogenase; TGFBR2, transforming growth factor β recep
Genotyping : One Piece of the Puzzle to Personalize Antiplatelet Therapy
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; genotyping; antiplatelet therapy; CYP2C19*2ADP, adenosine diphosphate; CYP, hepatic cytochrome P450; HPR, high on-treatment platelet reactivity; HR, hazard ratio; SNP, single-nucleotide polymorphism
Association of the manganese superoxide dismutase gene Ala–9Val polymorphism with clinical phenotypes and tardive dyskinesia in schizophrenic patients
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; AIMS, Abnormal Involuntary Movement Scale; ANOVA, one-way analysis of variance; MnSOD, manganese superoxide dismutase; PANSS, Positive and Negative Syndrome Scale; SNP, single-nucleotide polymorphism; TD, tardive dyskinesiaAssociation; Manganese superoxid
Interleukin 6–174 G/C promoter and variable number of tandem repeats (VNTR) gene polymorphisms in sporadic Alzheimer's disease
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; IL-6, interleukin 6; AD, Alzheimer's disease; APP, amyloid precursor protein; VNTR, variable number of tandem repeats; bp, base pairs; SNP, single-nucleotide polymorphism; APOE, apolipoprotein E; CDR, clinical dementia rating scale; CI, confidence interva
Association study of BDNF and DRD3 genes in schizophrenia diagnosis using matched case–control and family based study designs
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; SCZ, schizophrenia; DRD3, dopamine D3 receptor gene; BDNF, brain-derived neurotrophic factor gene; SNP, single-nucleotide polymorphism; GPCR, G-protein coupled receptor; ERK, extracellular signal regulated kinase; cAMP, cyclic Adenosine Mono-Phosphate; FB
Chromosome 4q25 Variants and Atrial Fibrillation Recurrence After Catheter Ablation
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; atrial fibrillation; gene variants; catheter ablationAF, atrial fibrillation; CI, confidence interval; ERAF, early recurrence of atrial fibrillation; LRAF, late recurrence of atrial fibrillation; OR, odds ratio; SNP, single-nucleotide polymorphism
Conserved recoding RNA editing of vertebrate C1q-related factor C1QL1
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; ADAR, adenosine deaminase acting on RNA; C1QL1, complement component 1, q subcomponent-like 1; SNP, single-nucleotide polymorphism; ECS, editing site complementary sequenceRNA editing; Inosine; Adenosine deaminase acting on RNA; Double-stranded RNA; Compl
Manganese superoxide dismutase gene Ala–9Val polymorphism might be related to the severity of abnormal involuntary movements in Korean schizophrenic patients
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; AIMS, Abnormal Involuntary Movement Scale; MnSOD, manganese superoxide dismutase; PANSS, Positive and Negative Syndrome Scale; ROS, reactive oxygen species; SNP, single-nucleotide polymorphism; SOD, superoxide dismutase; TD, Tardive dyskinesiaAbnormal inv
Genome-Wide Association Analysis in Sarcoidosis and Crohn's Disease Unravels a Common Susceptibility Locus on 10p12.2
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; BMBF, Bundesministerium für Bildung und Forschung; GWAS, genome-wide association analysis; LD, linkage disequilibrium; OR, odds ratio; SNP, single-nucleotide polymorphism; WTCCC, Wellcome Trust Case Control Consortium
Combined Functional and Positional Gene Information for the Identification of Susceptibility Variants in Celiac Disease
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; CD, celiac disease; IL, interleukin; MHC, major histocompatibility complex; SNP, single-nucleotide polymorphism
Future impact of integrated high-throughput methylome analyses on human health and disease
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; DNA methylation; reverse phenotyping; complex diseaseGWAS, genome-wide association study; SNP, single-nucleotide polymorphism; MVP, methylated variable position; CGI, CpG island; MeDIP, methylated DNA immunoprecipitation
Synonymous Mutations and Ribosome Stalling Can Lead to Altered Folding Pathways and Distinct Minima
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; SNP, single-nucleotide polymorphism; MDR1, multidrug resistance 1; P-gp, P-glycoprotein; ABC, ATP-binding cassette; OA, ovalbumin; OAR, renatured OA; OAN, native OA; CFTR, cystic fibrosis transmembrane conductance regulator; NBD, nucleotide binding domain
Arginine (CGC) codon targeting in the human prostacyclin receptor gene (PTGIR) and G-protein coupled receptors (GPCR)
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; PGI2, prostacyclin; hIP, human prostacyclin receptor; PTGIR, human prostacyclin receptor gene, GPCR, G-protein coupled receptor; TM, transmembrane; DMEM, Dulbecco's Modified Eagle's Medium; SNP, single-nucleotide polymorphism; dbSNP, SNP database; GPCRDB,
Haplotype of thrombomodulin gene associated with plasma thrombomodulin level and deep vein thrombosis in the Japanese population
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; DVT, deep vein thrombosis; TM, thrombomodulin; PC, protein C; APC, activated protein C; PS, protein S; EGF, epidermal growth factor; SNP, single-nucleotide polymorphism; sTM, soluble TM; 5′-UTR, 5′-untranslated region; 3′-UTR, 3′-untranslated regionThromb
Potential of Waxy gene microsatellite and single-nucleotide polymorphisms to develop japonica varieties with desired amylose levels in rice (Oryza sativa L.)
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; Ac, amylose content; EAN, Estação Agronómica Nacional; EtBr, ethidium bromide; GBSS, granule-bound starch synthase; MAS, marker-assisted selection; NPT, new plant type; SNP, single-nucleotide polymorphism; TBE, tris-borate EDTA buffer; Wx, Waxy geneAmylos
Interrogating genomic diversity of E. coli O157:H7 using DNA tiling arrays
Keywords: SNP، پلی مورفیسم تک نوکلئوتیدی; SNP, single-nucleotide polymorphism; MNP, multi-nucleotide polymorphism; CNP, copy number polymorphismTiling DNA microarray; Escherichia coli O157:H7; Single nucleotide polymorphism