
High affinity Grb2-SH3 domain ligand incorporating Cβ-substituted prolines in a Sos-derived decapeptide
Keywords: سس، آخرین هفتاد و نه; Grb2-SH3 domain; Cβ-substituted prolines; Fluorescence; ITCMAPK, mitogen-activated protein kinase; Grb2, growth factor receptor-bound protein 2; SH3, Src homology 3; PPII, polyproline II; Sos, son of sevenless; CD, circular dichroism; TKR, tyrosine kinase