
Structure and catalytic function of sphingosine kinases: Analysis by site-directed mutagenesis and enzyme kinetics
Keywords: ATP, adenosine 5′-triphosphate; SK, sphingosine kinase; hSK, human sphingosine kinase; mSK, mouse sphingosine kinase; SPH, d-erythro-sphingosine; S1P, d-erythro-sphingosine 1-phosphate; WT, wild typeSphingosine kinase; Sphingosine; Sphingosine 1-phosphate