
Efficient disruption of endogenous Bombyx gene by TAL effector nucleases
Keywords: Gene targeting; ZFN; Nonhomologous end joining; MMEJ; BmBLOS2; Chimeric nucleasesNHEJ, nonhomologous end joining; SD-MMEJ, synthesis-dependent microhomology-mediated end joining; HR, homologous recombination; ssa, single-strand annealing; ZF, zinc finger;