Keywords: ssDNA، DNA تک رشته ای; CEA, carcinoembryonic antigen; LFIA, lateral-flow immunoassay; MNPs, magnetic nanoparticles; ssDNA, single-stranded DNA; ECLIA, electrochemiluminescence immunoassay; GMBN, gold magnetic biofunctional nanobeads; MRI, magnetic resonance imaging; AuNPs, gold
مقالات ISI ssDNA، DNA تک رشته ای (ترجمه نشده)
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Keywords: ssDNA، DNA تک رشته ای; Fork collapse; Replication checkpoint; ATR; Replisome; iPONDATR, ATM and Rad3-related; RPA, Replication protein A; iPOND, Isolation of proteins on nascent DNA; ChIP, Chromatin immunoprecipitation; HU, Hydroxyurea; ssDNA, Single-stranded DNA
RAD51 variant proteins from human lung and kidney tumors exhibit DNA strand exchange defects
Keywords: ssDNA، DNA تک رشته ای; HR, homologous recombination; HDR, homology-directed (DNA) repair; DSB, DNA double-strand break; dsDNA, double-stranded DNA; ssDNA, single-stranded DNA; SSB, ssDNA binding protein; WT, wild-typeRAD51; Recombination; Homology-directed repair; Cancer; Varia
POT1–TPP1 Binding and Unfolding of Telomere DNA Discriminates against Structural Polymorphism
Keywords: ssDNA، DNA تک رشته ای; ss, single-stranded; ssDNA, single-stranded DNA; nt, nucleotide; POT1, Protection of telomeres 1; OB, oligonucleotide binding; SE-HPLC, size-exclusion HPLC; CD, circular dichroism; EMSA, electrophoretic mobility shift assays; TBE, Tris/Borate/EDTAtelomere
Isolation of a novel plasmid from Couchioplanes caeruleus and construction of two plasmid vectors for gene expression in Actinoplanes missouriensis
Keywords: ssDNA، DNA تک رشته ای; dsDNA, double-stranded DNA; dso, double-strand origin; RCR, rolling-circle replication; ssDNA, single-stranded DNA; sso, single-strand originActinoplanes missouriensis; Couchioplanes caeruleus; Rare actinomycetes; Rolling-circle replication; Plasmid; Shut
Yet another job for Dna2: Checkpoint activation
Keywords: ssDNA، DNA تک رشته ای; 9–1–1, human Rad9, Rad1, Hus1 (yeast Ddc1, Rad17, Mec3) checkpoint clamp; ATM, ataxia-telangiectasia mutated; ATR, ATM and Rad3–related; ATRIP, ATR interacting protein; DSB, double-strand break; dsDNA, double-stranded DNA; ssDNA, single-stranded DNA; FEN1
A Direct Interaction with RNA Dramatically Enhances the Catalytic Activity of the HIV-1 Protease In Vitro
Keywords: ssDNA، DNA تک رشته ای; HIV, human immunodeficiency virus; PFV, prototype foamy virus; MA, matrix; CA, capsid; NC, nucleocapsid; SP1, spacer peptide 1; SP2, spacer peptide 2; ssDNA, single-stranded DNA; NIH, National Institutes of HealthGag; Maturation; p15NC; Protease; Alloster
Beyond DnaA: The Role of DNA Topology and DNA Methylation in Bacterial Replication Initiation
Keywords: ssDNA، DNA تک رشته ای; NAP, nucleoid-associated protein; IHF, integration host factor; Fis, factor-for-inversion stimulation; ssDNA, single-stranded DNA; RNAP, RNA polymeraseDNA replication; orisome formation; DNA tertiary structure; oriC methylation; nucleoid-associated protei
Context-Dependent Remodeling of Rad51–DNA Complexes by Srs2 Is Mediated by a Specific Protein–Protein Interaction
Keywords: ssDNA، DNA تک رشته ای; ssDNA, single-stranded DNA; dsDNA, double-stranded DNA; HR, homologous recombination; EMSA, electrophoretic mobility shift analysis; smFRET, single-molecule FRET; EDTA, ethylenediaminetetraacetic acidSrs2; DNA unwinding; Rad51; homologous recombination; h
Diffusion of Human Replication Protein A along Single-Stranded DNA
Keywords: ssDNA، DNA تک رشته ای; RPA, replication protein A; ssDNA, single-stranded DNA; hRPA, human RPA; OB, oligonucleotide/oligosaccharide binding; smTIRF, single-molecule total internal reflectance fluorescence; dsDNA, double-stranded DNARPA; single-molecule fluorescence; dynamics; D
Optical sequence probing with the homologous recombination protein RecA
Keywords: ssDNA، DNA تک رشته ای; ssDNA, single-stranded DNA; dsDNA, double-stranded DNA; FISH, fluorescence in situ hybridization; DTT, dithiothreitol; BSA, bovine serum albuminRecA; Optical mapping; Homologous recombination; Electrostatic manipulation
Novel Interaction of the Bacterial-Like DnaG Primase with the MCM Helicase in Archaea
Keywords: ssDNA، DNA تک رشته ای; ssDNA, single-stranded DNA; pol–prim, polymerase α–primase complex; RFC, replication factor C; Sso, Sulfolobus solfataricus; TOPRIM, topoisomerase primase; Ec, Escherichia coli; EMSA, electrophoretic mobility shift assay; GST, glutathione S-transferase; M
Escherichia coli UmuC active site mutants: Effects on translesion DNA synthesis, mutagenesis and cell survival
Keywords: ssDNA، DNA تک رشته ای; pol, DNA polymerase; rNTPs, ribonucleotides; dNTPs, deoxyribonucleotides; ATPγS, adenosine 5′[γ-thio]triphosphate; CPD, cyclobutane pyrimidine dimer; ssDNA, single-stranded DNA; pol, DNA polymerase; SSB, single-stranded DNA binding protein; TLS, translesi
Plasmodium falciparum SSB Tetramer Wraps Single-Stranded DNA with Similar Topology but Opposite Polarity to E. coli SSB
Keywords: ssDNA، DNA تک رشته ای; TCEP, tris(2-carboxyethyl)phosphine; 2-ME, 2-mercaptoethanol; ALS, apicoplast localization signal; SSB, single-stranded DNA binding; ssDNA, single-stranded DNA; Pf-SSB, P. falciparum SSB; Ec-SSB, Escherichia coli SSB; PDB, Protein Data Bank; EDTA, ethylen
Adenosine induces apoptosis in the human gastric cancer cells via an intrinsic pathway relevant to activation of AMP-activated protein kinase
Keywords: ssDNA، DNA تک رشته ای; AIF, apoptosis-inducing factor; AMPK, AMP-activated protein kinase; MTT, 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide; PBS, phosphate-buffered saline; ssDNA, single-stranded DNA; 8-CPT, 8-cyclopentyltheophylline; DMPX, 3,7-dimethyl-1-p
Yeast mitochondrial DNA polymerase is a highly processive single-subunit enzyme
Keywords: ssDNA، DNA تک رشته ای; Polγ, polymerase γ; mtDNA, mitochondrial DNA; BSA, bovine serum albumine; USP, universal primer; MTS, mitochondrial targeting sequence; ssDNA, single-stranded DNA; kpol, polymerase catalytic constant; SSB, ssDNA binding proteinDNA polymerase γ; Mip1; Yeas
The DNA damage checkpoint allows recombination between divergent DNA sequences in budding yeast
Keywords: ssDNA، DNA تک رشته ای; DDR, DNA damage response; SSA, single-strand annealing; DSB, double-strand break; BIR, break-induced replication; HR, homologous recombination; ssDNA, single-stranded DNA; NHEJ, non-homologous end joining; SDSA, synthesis-dependent strand annealing; TLS,
Two Modes of Binding of DinI to RecA Filament Provide a New Insight into the Regulation of SOS Response by DinI Protein
Keywords: ssDNA، DNA تک رشته ای; RecA filament; DinI; bacterial SOS response; LexA cleavage; homologous recombinationCTD, C-terminal domain; dsDNA, double-stranded DNA; ssDNA, single-stranded DNA; 3D, three-dimensional; PDB, Protein Data Bank; IHRSR, Iterative Helical Real-Space Reconstr
The Stalk Region of the RecU Resolvase Is Essential for Holliday Junction Recognition and Distortion
Keywords: ssDNA، DNA تک رشته ای; Holliday junction resolvases; Hjc; RecU; RuvB; RecAHJ, Holliday junction; HR, homologous recombination; RecUBst, Bacillus stearothermophilus RecU; DAPI, 4′,6-diamidino-2-phenylindole; wt, wild type; dsDNA, double-stranded DNA; ssDNA, single-stranded DNA;
The Rate of Polymerase Release upon Filling the Gap between Okazaki Fragments Is Inadequate to Support Cycling during Lagging Strand Synthesis
Keywords: ssDNA، DNA تک رشته ای; SPR, surface plasmon resonance; ssDNA, single-stranded DNA; TCEP, tris(2-carboxyethyl)phosphine hydrochlorideDNA replication; Okazaki fragment synthesis; cycling; collision model; surface plasmon resonance
Characterization of a Dual-Function Domain That Mediates Membrane Insertion and Excision of Ff Filamentous Bacteriophage
Keywords: ssDNA، DNA تک رشته ای; ICS, infection-competence segment; ssDNA, single-stranded DNA; cC, complete C domain; WTpIII, wild-type pIII; PEG, polyethylene glycol; TBS, Tris-buffered saline; TAE, Tris–acetate–ethylenediaminetetraacetic acidviral infection; phage entry; g3p; membrane
Visualizing ATP-Dependent RNA Translocation by the NS3 Helicase from HCV
Keywords: ssDNA، DNA تک رشته ای; hepatitis C virus; helicase structure; molecular motor; protein-RNA complex; RNA translocationHCV, hepatitis C virus; NS3, nonstructural protein 3; SF2, superfamily 2; ssDNA, single-stranded DNA; ssRNA, single-stranded RNA; ss/ds junction, single-stranded
Heterochromatin DNA replication and Rif1
Keywords: ssDNA، DNA تک رشته ای; DSBs, double-strand breaks; HR, homologous recombination; BIR, break-induced repair; ES, embryonic stem; T-SCE, telomere sister chromatid exchanges; ssDNA, single-stranded DNA; siRNA, short interfering RNA; ATM, ataxia telangiectasia mutated; ATR, ataxia
Targeting human Rad51 by specific DNA aptamers induces inhibition of homologous recombination
Keywords: ssDNA، DNA تک رشته ای; Rad51 inhibitor; Homologous recombination; Aptamer; DNA strand exchangeHsRad51, human Rad51; SELEX, Systematic Evolution of Ligands by EXponential enrichment; ssDNA, single-stranded DNA; dsDNA, double-stranded DNA; CD, circular dichroism; 3-D structure, t
Pathways for Double-strand Break Repair in Genetically Unstable Z-DNA-forming Sequences
Keywords: ssDNA، DNA تک رشته ای; DSB, DNA double-strand break; NHEJ, non-homologous end-joining; HR, homologous recombination; ssDNA, single-stranded DNA; WT, wild type; LMPCR, linker-mediated PCR; Mt, Mycobacterium tuberculosisZ-DNA; DNA double-strand break; genetic instability; non-hom
APOBEC1 and APOBEC3 Cytidine Deaminases as Restriction Factors for Hepadnaviral Genomes in Non-Humans In Vivo
Keywords: ssDNA، DNA تک رشته ای; HBV, hepatitis B virus; HIV, human immunodeficiency virus; ssDNA, single-stranded DNA; IFN, interferon; WHV, woodchuck hepatitis virus; DHV, duck hepatitis virus; GE, genome equivalentmouse; HBV; APOBEC; restriction factor; cytidine deaminase
Single-Molecule Study of DNA Polymerization Activity of HIV-1 Reverse Transcriptase on DNA Templates
Keywords: ssDNA، DNA تک رشته ای; HIV-1 RT, human immunodeficiency virus type-1 reverse transcriptase; ssDNA, single-stranded DNA; SSB, single-stranded DNA binding protein; dsDNA, double-stranded DNA; kpe, primer extension rate; ksd, strand displacement rate; NC, nucleocapsidHIV-1 reverse
Human RECQL5 overcomes thymidine-induced replication stress
Keywords: ssDNA، DNA تک رشته ای; DSB, double strand break; dsDNA, double stranded DNA; HR, homologous recombination; MEFs, mouse embryonic fibroblasts; ssDNA, single-stranded DNA; TLS, translesion synthesisHomologous recombination; Thymidine; RECQL5; Replication
Unfinished Stories on Viral Quasispecies and Darwinian Views of Evolution
Keywords: ssDNA، DNA تک رشته ای; HIV-1, human immunodeficiency virus type 1; HCV, hepatitis C virus; HBV, hepatitis B virus; HAART, highly active antiretroviral therapy; ssDNA, single-stranded DNA; SIV, simian immunodeficiency viruscancer; superorganism; biofilm; disease; evolution
The Single-Stranded DNA Binding Protein of Sulfolobus solfataricus Acts in the Presynaptic Step of Homologous Recombination
Keywords: ssDNA، DNA تک رشته ای; SSB, single-stranded DNA binding protein; ssDNA, single-stranded DNA; SsoSSB, Sulfolobus solfataricus SSB; SsoRadA, Sulfolobus solfataricus RadA; RPA, replication protein A; EcoSSB, Escherichia coli SSB; EMSA, electrophoretic mobility shift assay; EDTA, e
Reversal of a Mutator Activity by a Nearby Fidelity-Neutral Substitution in the RB69 DNA Polymerase Binding Pocket
Keywords: ssDNA، DNA تک رشته ای; Exo; PoldsDNA, double-stranded DNA; ssDNA, single-stranded DNA
Molecular Analyses of an Unusual Translesion DNA Polymerase from Methanosarcina acetivorans C2A
Keywords: ssDNA، DNA تک رشته ای; CPD, cis–syn cyclobutane pyrimidine thymine–thymine dimer; PCNA, proliferating cell nuclear antigen; Pol, DNA polymerase; PIP, PCNA-interacting protein; RFC, replication factor C; RPA, replication protein A; ssDNA, single-stranded DNA; TLS, translesion DN
The Escherichia coli PriA Helicase–Double-Stranded DNA Complex: Location of the Strong DNA-Binding Subsite on the Helicase Domain of the Protein and the Affinity Control by the Two Nucleotide-Binding Sites of the Enzyme
Keywords: ssDNA، DNA تک رشته ای; dsDNA, double-stranded DNA; ssDNA, single-stranded DNA; PAS, primosome assembly sitemotor proteins; helicases; PriA protein; DNA binding; allosteric interactions
Effect of 1-methyladenine on thermodynamic stabilities of double-helical DNA structures
Keywords: ssDNA، DNA تک رشته ای; m1A, 1-methyladenine; m6A, N6-methyladenine; NMR, nuclear magnetic resonance; dsDNA, double-stranded DNA; ssDNA, single-stranded DNA; UV, ultra-violet; DSC, differential scanning calorimetry; PAGE, polyacrylamide gel electrophoresis; 1D, one-dimensional;
Cancer-Associated Mutations in BRC Domains of BRCA2 Affect Homologous Recombination Induced by Rad51
Keywords: ssDNA، DNA تک رشته ای; dsDNA, double-stranded DNA; ssDNA, single-stranded DNA; TAMRA, tetramethylrhodamineBRCA2; BRC domains; homologous recombination; mutations; Rad51
Mutagenesis identifies the critical regions and amino acid residues of suid herpesvirus 1 DNA-binding protein required for DNA binding and strand invasion
Keywords: ssDNA، DNA تک رشته ای; BSA, bovine serum albumin; DBP, DNA-binding protein; dsDNA, double-stranded DNA; E. coli, Escherichia coli; HSV-1, herpes simplex virus type 1; ssDNA, single-stranded DNA; SSB, ssDNA-binding protein; SDS–PAGE, sodium dodecyl sulfate–polyacrylamide gel ele
Cleavage of Bacteriophage λ cI Repressor Involves the RecA C-Terminal Domain
Keywords: ssDNA، DNA تک رشته ای; CTD, C-terminal domain; ssDNA, single-stranded DNA; dsDNA, double-stranded DNA; EM, electron microscopy; TM, triple mutant; wt, wild typeelectron microscopy; helical polymers; image processing; recombination
Dynamic Regulatory Interactions of Rad51, Rad52, and Replication Protein-A in Recombination Intermediates
Keywords: ssDNA، DNA تک رشته ای; RPA, replication protein-A; ssDNA, single-stranded DNA; DSB, double-strand break; HR, homologous recombination; SSA, single-strand annealing; dsDNA, double-stranded DNA; DAPI, 4′,6-diamidino-2-phenylindolehomologous recombination; genome integrity; single
Functional Importance of Bacteriophage ϕ29 DNA Polymerase Residue Tyr148 in Primer-terminus Stabilisation at the 3′-5′ Exonuclease Active Site
Keywords: ssDNA، DNA تک رشته ای; ssDNA, single-stranded DNA; pNP-TMP, 5′-p-nitrophenyl ester of thymidine 5′-monophosphate; Pol Ik, Klenow fragment of DNA polymerase Iϕ29 DNA polymerase; 3′-5′ exonuclease; site-directed mutagenesis; ssDNA binding; strand displacement
A Bridge Crosses the Active-Site Canyon of the Epstein–Barr Virus Nuclease with DNase and RNase Activities
Keywords: ssDNA، DNA تک رشته ای; dsDNA, double-stranded DNA; EBV, Epstein–Barr virus; NPC, nasopharyngeal carcinoma; ssDNA, single-stranded DNA; HSV, herpes simplex virus; NLS, nuclear localization signal; GFP, green fluorescent protein; WT, WT; KSHV, Kaposi-sarcoma-related herpesvirus;
Single-Stranded DNA-Binding Protein Complex from Helicobacter pylori Suggests an ssDNA-Binding Surface
Keywords: ssDNA، DNA تک رشته ای; SSB, single-stranded DNA-binding protein; OB-fold, oligonucleotide/oligosaccharide binding fold; ssDNA, single-stranded DNA; HpSSB, Helicobacter pylori SSB; HpSSBc, C-terminally truncated HpSSB; EcoSSB, Escherichia coli SSB; EMSA, electrophoretic mobility
Human Transcriptional Coactivator PC4 Stimulates DNA End Joining and Activates DSB Repair Activity
Keywords: ssDNA، DNA تک رشته ای; DSB, double-strand break; NHEJ, nonhomologous end joining; BSA, bovine serum albumin; AFM, atomic force microscopy; CTD, C-terminal domain; ssDNA, single-stranded DNA; dsDNA, double-stranded DNA; dNTP, deoxyribonucleotide triphosphate; HMGB1, high-mobilit
Role of Allosteric Switch Residue Histidine 195 in Maintaining Active-Site Asymmetry in Presynaptic Filaments of Bacteriophage T4 UvsX Recombinase
Keywords: ssDNA، DNA تک رشته ای; ssDNA, single-stranded DNA; EcRecA, Escherichia coli RecA; ScRad51, Saccharomyces cerevisiae Rad51; dsDNA, double-stranded DNA; RFIII, replicative fragment III; TLC, thin-layer chromatography; PPi, inorganic pyrophosphate; Pi, inorganic phosphate; EDTA, e
ATP Binding and Hydrolysis by Mcm2 Regulate DNA Binding by Mcm Complexes
Keywords: ssDNA، DNA تک رشته ای; Mcm, minichromosome maintenance; DDK, Dbf4-dependent kinase; Cdc, cell division control; ssDNA, single-stranded DNA; dsDNA, double-stranded DNA; PKA, protein kinase A; ATPγS, adenosine 5′-O-(3-thio)triphosphate; 5-FOA, 5-fluoroorotic acid; EDTA, ethylened
Murine APOBEC1 Is a Powerful Mutator of Retroviral and Cellular RNA InVitro and In Vivo
Keywords: ssDNA، DNA تک رشته ای; ssDNA, single-stranded DNA; HIV-1, human immunodeficiency virus type 1; apoB, apolipoprotein B; Fr–MLV, Friend–murine leukemia virus; 3D-PCR, differential DNA denaturation PCR; HPRT, hypoxanthine–guanine phosphoribosyl transferase; mACF, murine APOBEC1 co
Identification of the SSB Binding Site on E. coli RecQ Reveals a Conserved Surface for Binding SSB's C Terminus
Keywords: ssDNA، DNA تک رشته ای; SSB, single-stranded DNA binding protein; RPA, replication protein A; OB, oligosaccharide binding; ssDNA, single-stranded DNA; RecQ-WH, RecQ winged-helix; HSQC, heteronuclear single quantum coherence; 3D, three-dimensional; NOESY, nuclear Overhauser enhan
Molecular Interplay between the Replicative Helicase DnaC and Its Loader Protein DnaI from Geobacillus kaustophilus
Keywords: ssDNA، DNA تک رشته ای; dsDNA, double-stranded DNA; ssDNA, single-stranded DNA; BsDnaI, B. subtilis DnaI; SPR, surface plasmon resonance; NTP, nucleotide triphosphate; GST, glutathione S-transferase; ISM, initiator/loader-specific motif; PBS, phosphate-buffered salinereplication
Mechanism Analysis Indicates that Recombination Events in HIV-1 Initiate and Complete Over Short Distances, Explaining Why Recombination Frequencies Are Similar in Different Sections of the Genome
Keywords: ssDNA، DNA تک رشته ای; RNase, ribonuclease; PCIS, pre-created invasion site; RT, reverse transcriptase; NC, nucleocapsid protein; ssDNA, single-stranded DNA; PBS, primer binding site; DRNA, donor RNA; WT, wild type; DDNA, donor DNAHIV-1; reverse transcriptase; strand transfer;
Visualizing the Disassembly of S. cerevisiae Rad51 Nucleoprotein Filaments
Keywords: ssDNA، DNA تک رشته ای; AMP-PNP, adenosine 5'-(beta, gamma-imido) triphosphate; dsDNA, double-stranded DNA; DSB, dsDNA break; HR, homologous recombination; ssDNA, single-stranded DNA; TIRFM, total internal reflection fluorescence microscopy; QD, quantum dot; BSA, bovine serum al
Effect of 1-methyladenine on double-helical DNA structures
Keywords: ssDNA، DNA تک رشته ای; m1A, 1-methyladenine; m6A, N6-methyladenine; NMR, nuclear magnetic resonance; dsDNA, double-stranded DNA; ssDNA, single-stranded DNA; PAGE, polyacrylamide gel electrophoresis; 1D, one-dimensional; 2D, two-dimensional; NOE, nuclear Overhauser effect; NOESY