دانلود مقالات ISI درباره دقت استاندارد + ترجمه فارسی

سنتز مشتقات اگزیدا دیازول و آمید بر اساس پریازول اکریلیک اسید به عنوان داروهای ضد مالاریا و ضد سرطانی

Synthesis of pyrazole acrylic acid based oxadiazole and amide derivatives as antimalarial and anticancer agents

Keywords: دقت استاندارد; HOBt; hydroxybenzotriazole; EDCl; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide; DMF; N-N-dimethyl formamide; s; singlet; 5-FU; 5-fluorouracil; P. falciparum; Plasmodium falciparum; SI; Selectivity Index; TLC; Thin Layer Chromatography; IR; infra-red; NMR

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2018 سفارش ترجمه

بررسی داروهای جدید برای بیماری گوچر

Investigation of novel pharmacological chaperones for Gaucher Disease

Keywords: دقت استاندارد; GBA; Glucocerebrosidase; MD; Molecular Dynamics; GD; Gaucher Disease; PC; Pharmacological Chaperone; SP; Standard Precision; XP; Extra Precision; GBA; Gaucher disease; Molecular docking; Substructure search; Molecular dynamics; Blood brain barrier; Pharma

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2017 سفارش ترجمه

A Computational workflow for the identification of the potent inhibitor of type II secretion system traffic ATPase of Pseudomonas aeruginosa

Keywords: دقت استاندارد; kj/mol; kilojoule per mol; MD; molecular dynamics; MM; molecular mechanics; MM-GBSA; molecular mechanics - generalized born and surface area; OPLS; optimized potential for liquid simulations; GBSA; generalized-born surface area; PME; particle mesh ewa

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2018 سفارش ترجمه

Oroxin A from Oroxylum indicum prevents the progression from prediabetes to diabetes in streptozotocin and high-fat diet induced mice

Keywords: دقت استاندارد; Oroxin A; Prediabetes; Type 2 diabetes; PPARγ; Mechanism; 2h-PG; 2-h postprandial glucose; ALT; alanine transaminase; AST; aspartate transaminase; AUC; area under the curve; CMC-Na; Sodium carboxymethylcellulose; CαRMSD; Cα root mean square deviation;

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

E7 oncoprotein of human papillomavirus: Structural dynamics and inhibitor screening study

Keywords: دقت استاندارد; HPV; Human papillomavirus; pRB; Phosphorylated Retiboblastoma; 3D; Three dimensional; MoRFs; Molecular recognition features; DNA; Deoxyribo nucleic acid; CRs; Conserved regions; IDPs; Intrinsically disordered proteins; CD-HIT; Cluster database at high ide

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2018 سفارش ترجمه

Ensemble docking-based virtual screening yields novel spirocyclic JAK1 inhibitors

Keywords: دقت استاندارد; AUC; area under the (ROC) curve; EF; enrichment factor; FDA; Food and Drug Administration; FPR; false positive rate; HTVS; high throughput virtual screening; JAK; Janus kinase; LLE; lipophilic ligand efficiency; LELP; lipophilicity-corrected ligand effici

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Pharmacological properties and predicted binding mode of arylmethylene quinuclidine-like derivatives at the α3β4 nicotinic acetylcholine receptor (nAChR)

Keywords: دقت استاندارد; ACHBP; acetylcholine-binding protein; Ach; acetylcholine; CNS; central nervous system; MEC; minimum-effective concentration; nAChR; nicotinic acetylcholine receptor; NIC; nicotine; Pdb; protein databank; rmsd; root-mean-squared-deviation; ROC; receiver op

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

QM-polarized ligand docking accurately predicts the trend in binding affinity of a series of arylmethylene quinuclidine-like derivatives at the α4β2 and α3β4 nicotinic acetylcholine receptors (nAChRs)

Keywords: دقت استاندارد; ACHBP; acetylcholine-binding protein; Ach; acetylcholine; CNS; central nervous system; MEC; minimum-effective concentration; nAChR; nicotinic acetylcholine receptor; NIC; nicotine; Pdb; protein databank; rmsd; root-mean-squared-deviation; ROC; receiver op

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Development of peptide inhibitor as a therapeutic agent against head and neck squamous cell carcinoma (HNSCC) targeting p38α MAP kinase

Keywords: دقت استاندارد; MAPK; mitogen activated protein kinase; HNSCC; head and neck squamous cell carcinoma; MKK; MAPK kinase; MKKK; MKK kinase; LB; Luria-Bertani; IPTG; isopropyl-ß-d-galactosidase; DLS; dynamic light scattering; ATF; activated transcription factor; NPP; 4-nit

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Inhibition in vivo of the activity of botulinum neurotoxin A by small molecules selected by virtual screening

Keywords: دقت استاندارد; Botulinum neurotoxin A; Small molecule inhibitors; Virtual screening; In vivo activity; Mouse protection assay; BoNT; botulinum neurotoxin; Glide; Grid-based ligand docking energetics; MPA; mouse protection assay; SP; Standard precision; VS; virtual scre

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه