Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; Angiogenesis; Chronic subdural hematoma; STAT3CSDH, Chronic subdural hematoma; IL-6, Interleukin-6; JAK, Janus kinase; STAT, Signal transducer and activator of transcription; STAT3, Signal transducer and activator of transcription 3; VEGF, Vascular endoth
مقالات ISI STAT3، مبدل سیگنال و فعال کننده رونویسی 3 (ترجمه نشده)
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Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; N. sativa, Nigella sativa; TQ, thymoquinone; NF-κB, nuclear factor-κB; STAT3, signal transducer and activator of transcription 3; MAPK, mitogen-activated protein kinases; PPAR-γ, peroxisome proliferator-activated receptor gamma; AKt, protein kinase B; LTC
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; CYP19, aromatase enzyme; ER, estrogen receptor; T, testosterone; E2, estradiol; STAT3, signal transducer and activator of transcription 3; SDS, standard deviation score; BMI, body mass index; FSH, Follicle stimulating hormone; LH, luteinizing hormone; DHE
Transient expression of Fc-fused human glycoprotein 130 in Expi293F suspension cells
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; Glycoprotein 130; Fc fragment; Expi293F; Transient expressionGp130, Glycoprotein 130; STAT3, signal transducer and activator of transcription 3; DMEM, Dulbecco modified essential medium; PBS, Phosphate buffer solution; PBST, PBS with 0.02% Tween-20; PVDF,
Colorectal cancer cell-derived interleukin-6 enhances the phagocytic capacity and migration of THP-1 cells
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; CRC, colorectal cancer; IL-6, interleukin-6; STAT3, signal transducer and activator of transcription 3; TAMs, tumor-associated macrophagesInterleukin-6; Macrophages; Colorectal cancer; Phagocytosis; Migration
Cyclosporine A sensitizes human non-small cell lung cancer cells to gefitinib through inhibition of STAT3
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; Cyclosporine A; EGFR–TKI; Lung cancer; STAT3NSCLC, non-small cell lung cancer; EGFR, epidermal growth factor receptor; TKI, tyrosine kinase inhibitor; STAT3, signal transducer and activator of transcription 3; CsA, cyclosporine A; CypA, cyclophilin A; MDR
Role of the anti-glioma drug AT13148 in the inhibition of Notch signaling pathway
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; GO, (Gene Oncology); DEGs, differentially expressed genes; KEGG, Kyoto Encyclopedia of Genes and Genomes; GBMg, glioblastomamultiforme; NF-κB, nuclear factor κB; STAT3, signal transducer and activator of transcription 3; DTX1, deltex homolog 1; MAML1, mas
Evolution in medicinal chemistry of ursolic acid derivatives as anticancer agents
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; Natural products; Ursolic acid derivatives; Anticancer agents; Drug discovery; Chemical biologyUA, ursolic acid; NF-κB, nuclear factor-κB; STAT3, signal transducer and activator of transcription 3; TRAIL, tumor necrosis factor (TNF)-related apoptosis indu
The STAT3 inhibitor WP1066 reverses the resistance of chronic lymphocytic leukemia cells to histone deacetylase inhibitors induced by interleukin-6
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; CLL, chronic lymphocytic leukemia; BMSCs, bone marrow stromal cells; IL-6, interleukin-6; IL-1β, interleukin-1β; bFGF, basic fibroblast growth factor; SDF-1, stromal cell-derived factor-1; STAT3, signal transducer and activator of transcription 3; HDACs,
Sorafenib Sensitizes Glioma Cells to the BH3 Mimetic ABT-737 by Targeting MCL1 in a STAT3-Dependent Manner 12
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; ATF5, activating transcrpition factor 5; MCL1, myeloid cell leukemia 1; STAT3, signal transducer and activator of transcription 3
STAT3 regulated ATR via microRNA-383 to control DNA damage to affect apoptosis in A431 cells
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; STAT3, signal transducer and activator of transcription 3; 3′ UTR, 3′ untranslated regions; UV, ultraviolet radiation; PIKK, phosphatidylinositol 3-kinase-related kinase; ATM, the ataxia telangiectasia-mutated; ATR, Rad3-related; CHK1, checkpoint kinase 1
RhoC Mediates Epidermal Growth Factor-Stimulated Migration and Invasion in Head and Neck Squamous Cell Carcinoma
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; EGFR, epidermal growth factor receptor; EGF, epidermal growth factor; HNSCC, head a neck squamous cell carcinoma; PI3K, phosphatidylinositol 3-kinase; STAT3, signal transducer and activator of transcription 3; EMT, epithelial mesenchymal transition; GSK3β
STAT3-mediated MMP-2 expression is required for 15-HETE-induced vascular adventitial fibroblast migration
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; 15-HETE, 15-hydroxy-eicosatetraenoicacid; VAFs, vascular adventitial fibroblasts; MMP-2, matrix metalloproteinase-2; α-SMA, alpha smooth muscle actin; STAT3, signal transducer and activator of transcription 3; CREB, cAMP-response element binding protein;
Predominant Activation of JAK/STAT3 Pathway by Interleukin-6 Is Implicated in Hepatocarcinogenesis 12
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; IL6, interleukin-6; JAK, Janus kinase; STAT3, signal transducer and activator of transcription 3; PI3K, phosphoinositide 3-kinase; MAPK, mitogen activated protein kinase; LFABP, liver fatty acid binding protein; RS6K, ribosomal S6 kinase; HCC, hepatocellu
Sugiol inhibits STAT3 activity via regulation of transketolase and ROS-mediated ERK activation in DU145 prostate carcinoma cells
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; STAT3, signal transducer and activator of transcription 3; EGFR, epidermal growth factor receptor; PDGFR, platelet-derived growth factor receptor; JAK, Janus-activated kinases; DCF-DA, 2,7-dichlorofluorescein diacetate; NAC, N-acetylcysteine; GSH, glutath
Ascochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; Ascochlorin; HCC; STAT3; PIAS3; Invasion; Orthotopic modelASC, ascochlorin; STAT3, signal transducer and activator of transcription 3; HCC, hepatocellular carcinoma; FBS, fetal bovine serum; MTT, 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyl-2H-tetrazolium
Influence of vitamin C and vitamin E on redox signaling: Implications for exercise adaptations
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; 5-LOX; 5-lipoxygenase; AP-1; activating protein 1; cGMP; cyclic guanosine monophosphate; ERK; extracellular signal-regulated kinase; GSH; glutathione (reduced); GSSG; glutathione (oxidized); H2O2; hydrogen peroxide; HIF-α; hypoxia inducible factor alpha;
Interleukin-17A in lipid metabolism and atherosclerosis
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; IL-17, interleukin-17; Th17, T helper 17; IL-17R, IL-17 receptor; STAT3, signal transducer and activator of transcription 3; RORγ, retinoic acid receptor-related orphan receptor γ; IRF4, interferon regulatory factor 4; ERK, extracellular signal-regulated
Stat3 signaling activation crosslinking of TGF-β1 in hepatic stellate cell exacerbates liver injury and fibrosis
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; ECM, extracellular matrix; HSCs, hepatic stellate cells; TGF-β1, transforming growth factor-β1; Col 1, collagen I; α-SMA, α-smooth muscle actin; Stat3, signal transducer and activator of transcription 3; Jak, Janus tyrosine kinase; GH, growth hormone; CHB
Bone marrow-derived myofibroblasts promote colon tumorigenesis through the IL-6/JAK2/STAT3 pathway
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; BMFs, bone marrow-derived myofibroblasts; BMF-CM, BMF conditioned medium; Co-culture-CM, co-culture medium of BMFs and cancer cells; IL-6, interleukin-6; JAK2, janus kinase 2; STAT3, signal transducer and activator of transcription 3; CAFs, cancer-associa
GRIM-19 inhibits the STAT3 signaling pathway and sensitizes gastric cancer cells to radiation
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; RA, retinoid acid; GRIMs, genes associated retinoid–IFN induced mortality; STAT3, signal transducer and activator of transcription 3; IR, irradiation; HRP, horseradish peroxidase; DAB, 3,3′-diaminobenzidine tetrahydrochloride; FCM, flow cytometric; PBS, p
Stat3 pathway correlates with the roles of leptin in mouse liver fibrosis and sterol regulatory element binding protein-1c expression of rat hepatic stellate cells
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; Jak2, Janus kinase 2; Stat3, signal transducer and activator of transcription 3; HSC, hepatic stellate cell; SREBP-1c, sterol regulatory element binding protein-1c; LXR, liver X receptor; FBS, fetal bovine serum; DMEM, Dulbecco's modified Eagle's medium;
The expression of glia maturation factors and the effect of glia maturation factor-γ on angiogenic sprouting in zebrafish
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; dpf, days postfertilization; hpf, hours postfertilization; MO, morpholino oligonucleotide; EC, endothelial cell; ISV, intersegmental vessel; CV, cardinal vein; STAT3, Signal Transducer and Activator of Transcription 3; VEGF-A, vascular endothelial growth
Thymoquinone: Potential cure for inflammatory disorders and cancer
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; PTEN, phosphatase and tensin homolog; STAT3, signal transducer and activator of transcription 3; PPAR-γ, peroxisome proliferator-activated receptors gamma; ROS, reactive oxygen species; NO, nitric oxide; TNF-α, tumor necrosis factor; IL, interleukin; MAPK
Activation of a pro-survival pathway IL-6/JAK2/STAT3 contributes to glial fibrillary acidic protein induction during the cholera toxin-induced differentiation of C6 malignant glioma cells
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; Interleukin-6; Janus kinase-2; Signal transducer and activator of transcription 3; Glioma; Glial fibrillary acidic protein; Cholera toxinIL-6, Interleukin-6; JAK2, Janus kinase-2; STAT3, Signal transducer and activator of transcription 3; GFAP, Glial fibr
Identification of C1qTNF-related protein 4 as a potential cytokine that stimulates the STAT3 and NF-κB pathways and promotes cell survival in human cancer cells
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; CTRP4; NF-κB; IL6/STAT3; Cancer related inflammation; Cancer therapyCTRP4/C1qTNF4, C1qTNF-related protein 4; IL6, interleukin 6; STAT3, signal transducer and activator of transcription 3; CHX, cycloheximide
Transcriptomics of enterotoxigenic Escherichia coli infection. Individual variation in intestinal gene expression correlates with intestinal function
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; CYP3A29, cytochrome P450 3A29; ETEC, enterotoxigenic E. coli; MMP1, matrix metalloproteinase-1; PAP, pancreatitis associated protein; STAT3, signal transducer and activator of transcription 3; THOC4, THO complex 4Enterotoxigenic E. coli; Host–pathogen int
Diosgenin, a steroidal saponin, inhibits STAT3 signaling pathway leading to suppression of proliferation and chemosensitization of human hepatocellular carcinoma cells
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; STAT3, signal transducer and activator of transcription 3; HCC, hepatocellular carcinoma; FBS, fetal bovine serum; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromideSTAT3; JAK2; Diosgenin; Hepatocellular carcinoma; Apoptosis
Interruption of β-catenin suppresses the EGFR pathway by blocking multiple oncogenic targets in human glioma cells
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; Glioma; β-catenin; EGFR; Signaling pathwayEGFR, epidermal growth factor receptor; STAT3, signal transducer and activator of transcription 3; AKT, AKT protein family, which members are also called protein kinases B; MMP2, matrix metalloproteinase-2; MMP9,
Noradrenaline acting at central β-adrenoceptors induces interleukin-10 and suppressor of cytokine signaling-3 expression in rat brain: Implications for neurodegeneration
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; IL-10; SOCS3; Noradrenaline; β-Adrenoceptor; STAT3; Brain; Anti-inflammatoryTyk2, non-receptor tyrosine-protein kinase 2; Jak1, Janus kinase 1; SOCS3, suppressor of cytokine signalling 3; STAT3, signal transducer and activator of transcription 3; SBE, STA
Leptin upregulates VEGF in breast cancer via canonic and non-canonical signalling pathways and NFκB/HIF-1α activation
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; MT, mammary tumor cells; VEGF, vascular endothelial growth factor; VEGFR2, vascular endothelial growth factor receptor 2; ER, estrogen receptor; JAK2, Janus kinase 2; STAT3, signal transducer and activator of transcription 3; ERK 1/2, extracellular signal
c-Jun NH2-terminal kinase mediates leptin-stimulated androgen-independent prostate cancer cell proliferation via signal transducer and activator of transcription 3 and Akt
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; AIPC, androgen-independent prostate cancer; IGF-I, insulin-like growth factor-I; IL-6, interleukin-6; STAT3, signal transducer and activator of transcription 3; PI3K, phosphatidylinositol-3 kinase; JNK, c-Jun NH2-terminal kinase; JAK, Janus kinase; SIE, s
β-Catenin/TCF pathway upregulates STAT3 expression in human esophageal squamous cell carcinoma
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; ESCC, esophageal squamous cell carcinoma; EC, esophageal cancer; STAT3, signal transducer and activator of transcription 3; TCF, T-cell Factor; TBE, TCF4-binding element; TSS, transcription start siteβ-catenin/TCF; STAT3; ESCC; Target gene; Overexpression
The early transcriptional response of pig small intestinal mucosa to invasion by Salmonella enterica serovar typhimurium DT104
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; CYP3A, cytochrome P450 3A29; ETEC, enterotoxic E. coli; MMP-1, matrix metalloproteinase-1; PAP, pancreatitis associated protein; SISP, small intestinal segment perfusion; STAT3, signal transducer and activator of transcription 3; TM4SF20, transmembrane 4L
Abrogation of constitutive STAT3 activity sensitizes human hepatoma cells to TRAIL-mediated apoptosis
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; JAK2, Janus kinase 2; SOCS, suppressor of cytokine signaling; STAT3, signal transducer and activator of transcription 3; TRAIL, tumor necrosis factor-related apoptosis-inducing ligandSTAT3; AG490; TRAIL; Hepatoma
Liver regeneration is suppressed in alcoholic cirrhosis: correlation with decreased STAT3 activation
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; Alcohol; STAT3; Liver regeneration; Cirrhosis; HCV; Cell proliferationHCV, hepatitis C virus; STAT3, signal transducer and activator of transcription 3; AST, aspartate transaminase; ALP, alkaline phosphatase
CD40 mediated human cholangiocyte apoptosis requires JAK2 dependent activation of STAT3 in addition to activation of JNK1/2 and ERK1/2
Keywords: STAT3، مبدل سیگنال و فعال کننده رونویسی 3; PBC, primary biliary cirrhosis; TNFR, tumour necrosis factor receptor; FasL, Fas ligand; Mab, monoclonal antibody; TNF-α, tumour necrosis factor-alpha; STAT3, signal transducer and activator of transcription 3; pSTAT3, phospho-STAT3; JAK1/2/3, janus tyros