Keywords: Clavulanic acid; Fed-batch fermentation; Streptomyces clavuligerus; Threonine; Arginine
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Screening of medium constituents for clavulanic acid production by Streptomyces clavuligerus
Keywords: Clavulanic acid; Streptomyces clavuligerus; Ferrous sulfate; Amino acids supplementation;
Proteome-wide alterations in an industrial clavulanic acid producing strain of Streptomyces clavuligerus
Keywords: Clavulanic acid; Streptomyces clavuligerus; Industrial strain; Proteomics; 2DE; MALDI-TOF/MS;
Purification of clavulanic acid produced by Streptomyces clavuligerus via submerged fermentation using polyethylene glycol/cholinium chloride aqueous two-phase systems
Keywords: Clavulanic acid; Aqueous two-phase systems; Polyethylene glycol; Cholinium chloride; Streptomyces clavuligerus;
An improved HPLC-DAD method for clavulanic acid quantification in fermentation broths of Streptomyces clavuligerus
Keywords: Clavulanic acid; Streptomyces clavuligerus; High performance liquid chromatography method; Fermentation processes; Clavulanate–imidazole
Heterologous expression of Streptomyces clavuligerus ATCC 27064 cephamycin C gene cluster
Keywords: Cephamycin C; Streptomyces clavuligerus; CcaR regulatory protein; Heterologous expression; Streptomyces flavogriseus;
Transcriptional analysis and proteomics of the holomycin gene cluster in overproducer mutants of Streptomyces clavuligerus
Keywords: Holomycin; hlm genes; Streptomyces clavuligerus; Heterologous expression;
Production of clavulanic acid by Streptomyces clavuligerus in batch cultures without and with glycerol pulses under different temperature conditions
Keywords: Clavulanic acid; Streptomyces clavuligerus; Temperature reduction; Glycerol uptake rate; Product degradation rate
A stable liquid–liquid extraction system for clavulanic acid using polymer-based aqueous two-phase systems
Keywords: Clavulanic acid; Aqueous two-phase systems; Poly(ethylene glycol); Poly(acrylic acid); Streptomyces clavuligerus
Optimisation of the glycerol-to-ornithine molar ratio in the feed medium for the continuous production of clavulanic acid by Streptomyces clavuligerus
Keywords: Clavulanic acid; Submerged culture; Streptomyces clavuligerus; Continuous culture; Glycerol; Ornithine; Bioprocess design; Optimisation
Aspects on evolution of fungal β-lactam biosynthesis gene clusters and recruitment of trans-acting factors
Keywords: Streptomyces clavuligerus; Aspergillus nidulans; Penicillium chrysogenum; Acremonium chrysogenum; Horizontal gene transfer; β-Lactam antibiotics; Penicillin; Cephalosporin; Regulators;
Isolation and identification of a novel microorganism producing the immunosuppressant tacrolimus
Keywords: tacrolimus; immunosuppressant; Streptomyces clavuligerus
Clavulanic acid: A review
Keywords: Clavulanic acid; Streptomyces clavuligerus; β-lactamase inhibitor; Secondary metabolite
Two-step purification of a highly thermostable alkaline protease from salt-tolerant alkaliphilic Streptomyces clavuligerus strain Mit-1
Keywords: Two-step purification of alkaline protease; Salt-tolerant alkaliphilic actinomycete; Streptomyces clavuligerus; Thermostable alkaline protease
Utilization of soybean derivatives on clavulanic acid production by Streptomyces clavuligerus
Keywords: Clavulanic acid; Streptomyces clavuligerus; Soybean flour; Soybean protein isolate; Soybean oil; Lipid
Application of lat gene disruption to increase the clavulanic acid production of Streptomyces clavuligerus
Keywords: Streptomyces clavuligerus; Clavulanic acid; Lat; Gene disruption
Optimization of medium composition for the production of clavulanic acid by Streptomyces clavuligerus
Keywords: Streptomyces clavuligerus; Clavulanic acid; Optimization; Medium composition;
Evolution of β-lactam biosynthesis genes and recruitment of trans-acting factors
Keywords: Streptomyces clavuligerus; Aspergillus nidulans; Penicillium chrysogenum; Acremonium chrysogenum; Horizontal gene transfer; β-Lactam antibiotics; Penicillin; Cephalosporin; Regulators;