Post-translational modifications in host cells during bacterial infection
Keywords: Rho GTPase; Cytoskeleton; Ubiquitin; MAPK; SUMO; Pathogenesis; Listeria;
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The small ubiquitin-like modifier (SUMO) is essential in cell cycle regulation in Trypanosoma brucei
Keywords: SUMO; Trypanosoma brucei; Cell cycle; Mitosis; Chromosome segregation
Positively charged amino acids flanking a sumoylation consensus tetramer on the 110Â kDa tri-snRNP component SART1 enhance sumoylation efficiency
Keywords: Bis-Tris; 2-[bis(2-hydroxyethyl)amino]-2-(hydroxymethyl)propane-1,3-diol; E1; SUMO activating enzyme; E2; SUMO protein carrier protein; E3; SUMO ligase; Fmoc; 9H-fluorenylmethyloxycarbonyl; IPTG; isopropyl-β-D-thiogalactopyranoside; NMM; N-methylmorpholi
Sumoylation controls retinal progenitor proliferation by repressing cell cycle exit in Xenopus laevis
Keywords: Ubc9; Sumo; Xenopus; Retina; Cell cycle; Progenitor;
Repression of interferon-α stimulated genes expression by Kaposi's sarcoma-associated herpesvirus K-bZIP protein
Keywords: KSHV; Interferon; Sumo; K-bZIP; Interferon-responsive genes; CBP; Herpes
Targets and consequences of protein SUMOylation in neurons
Keywords: SUMO; Ubc9; Ubiquitin; SENP; Post-translational modification; Neuronal function
SUMOylation of RORα potentiates transcriptional activation function
Keywords: SUMO, small ubiquitin-like modifier; RORα, retinoic acid receptor-related orphan receptor α; RORE, ROR response element; PML, promyelocytic leukemia protein; PIAS, protein inhibitor of activated STAT; SENP, SUMO-specific proteaseRORα; SUMO; SUMOylation; d
Analysis of in vitro SUMOylation using bioluminescence resonance energy transfer (BRET)
Keywords: SUMO; Energy transfer; BRET; FRET; RanGAP; Luciferase
Enhanced SUMOylation of proteins containing a SUMO-interacting motif by SUMO-Ubc9 fusion
Keywords: SUMO; Ubc9; SUMO-interacting motif; SIM; IE2; Sp100; HCMV
Molecular cloning, expression, and bioactivity of dove B lymphocyte stimulator (doBAFF)
Keywords: Dove B lymphocyte stimulator; SUMO; Fusion protein; B cells survival;
Host cell sumoylation level influences papillomavirus E2 protein stability
Keywords: HPV; SUMO; Proteasome; Post-translational modification
Emerging roles of desumoylating enzymes
Keywords: Desumoylation enzyme; SUMO; Ulp; SENP; SUMO isoform
Regulation of p53 family members by the ubiquitin-like SUMO system
Keywords: SUMO; p53 family; p63; p73; Ubiquitin
The Yin and Yang of the MMS21–SMC5/6 SUMO ligase complex in homologous recombination
Keywords: MMS21; NSE2; SUMO; SMC5; SMC6; Homologous recombination; DNA repair
Genome stability roles of SUMO-targeted ubiquitin ligases
Keywords: Ubiquitin; SUMO; STUbL; Proteasome; Degradation; SUMO-interaction motif; Ubiquitin ligase; DNA repair; Genome stability
SUMO association with repressor complexes, emerging routes for transcriptional control
Keywords: SUMO; SIM; Transcription repression; Chromatin remodelling; Heterochromatin; HDAC
Regulating post-translational modifications of the eukaryotic replication clamp PCNA
Keywords: DNA damage tolerance; Translesion synthesis; PCNA; Ubiquitin; SUMO; RAD6 pathway; Rad18; RPA; DNA; Ubc9; Siz1
Sumo-2/3-ylation following in vitro modeled ischemia is reduced in delayed ischemic tolerance
Keywords: Hypothermia; Ischemia; OGD; Neurons; Preconditioning; Sumo; Tolerance cycloheximide
Molecular determinants of kainate receptor trafficking
Keywords: glutamate receptors; trafficking; cytoplasmic domains; intracellular partners; AMPAR; AMPA receptor; COPI; coatomer protein complex I; ER; endoplasmic reticulum; Is(AHP); slow Ca2+-activated K+ current; KAR; kainate receptor; PKA; cAMP-dependent protein k
BS69 undergoes SUMO modification and plays an inhibitory role in muscle and neuronal differentiation
Keywords: BS69; SUMO; Neuronal differentiation; Muscle differentiation
SUMO Modification of DNA topoisomerase II: Trying to get a CENse of it all
Keywords: DNA topoisomerase II; SUMO; Sumoylation; Mitosis; Centromere; Kinetochore; Spindle assembly checkpoint; Aurora B/Ipl1; Chromosome segregation; Chromosome dynamics
Mel-18 interacts with RanGAP1 and inhibits its sumoylation
Keywords: RanGAP1; Mel-18; Polycomb; SUMO; SUMO-1; Mitosis;
Ubc9-mediated sumoylation leads to transcriptional repression of IRF-1
Keywords: IRF; Ubc9; SUMO; Transcriptional repression; SumoylationAD, transcriptional activation domain; DBD, DNA-binding domain; OD, oligomerization domain; HA, hemagglutinin; GST, glutathione S-transferase; ONPG, p-nitrophenyl-d-galactopyranoside; β-gal, β-galact
Nuclear localization of Rad52 is pre-requisite for its sumoylation
Keywords: Homologous recombination; Mating-switching; Sister chromatid recombination; Rad52; Rad52- K200R; Rad52-3KR; SUMO; Ubc9; NLS; S. cerevisiae;
Analysis of SUMO-1 modification of neuronal proteins containing consensus SUMOylation motifs
Keywords: SUMO; Posttranslational modification; SUMOylation; Metabotropic glutamate receptors; Group III mGluRs; Kainate receptor; GluR7; Synaptic protein
The IL-6 family of cytokines modulates STAT3 activation by desumoylation of PML through SENP1 induction
Keywords: IL-6; LIF; SENP1; SUMO; STAT3; PML; Transcriptional regulation
Redox-mediated modification of PLZF by SUMO-1 and ubiquitin
Keywords: SUMO; Ubiquitin; PLZF; ROS; Serum deprivation
Ku70 is stabilized by increased cellular SUMO
Keywords: DNA repair; SUMO; Ku70;
Aging and dietary restriction effects on ubiquitination, sumoylation, and the proteasome in the heart
Keywords: AL, ad libitum; DR, dietary restriction; NIA, National Institute of Aging; POMP, proteasome maturation protein; ROS, reactive oxygen species; Sumo, small ubiquitin-like modifier; Ub, ubiquitinAging; Heart; Oxidative stress; Proteasome; Sumo; Ubiquitin
Expression, purification and crystallization of cysteine-rich human protein muskelin in Escherichia coli
Keywords: β-Barrel; β-Propeller; SUMO; Crystallization; Muskelin
Ubiquitin and ubiquitin-like specific proteases targeted by infectious pathogens: Emerging patterns and molecular principles
Keywords: OTU; ovarian tumor domain; UBP; ubiquitin processing protease; UCH; ubiquitin C-terminal hydrolase; ULP; ubiquitin-like specific protease; USP; ubiquitin specific protease; Ubl; ubiquitin-like protein; Bacteria; Hydrolase; ISG15; Nedd8; Protease; SUMO; Ub
Sumoylation in Aspergillus nidulans: sumO inactivation, overexpression and live-cell imaging
Keywords: SUMO; Conidiation; Sexual development; Fusion PCR; Cell cycle
Increased protein SUMOylation following focal cerebral ischemia
Keywords: SUMO; Ischemia; Stroke; Kainate receptor; AMPA receptor; Posttranslational modification
Developmental control of sumoylation pathway proteins in mouse male germ cells
Keywords: SUMO; Sumoylation; Spermatogenesis; UBE2I; SUMO ligases; SUMO proteases; XY body; Meiosis; Spermatocytes; Male germ cells
Architecture and Assembly of Poly-SUMO Chains on PCNA in Saccharomyces cerevisiae
Keywords: PCNA, proliferating cell nuclear antigen; SUMO, small ubiquitin-like modifier; MMS, methyl methane sulfonate; 4-NQO, 4-nitroquinoline oxide; WT, wild typeposttranslational protein modifications; SUMO; Ubc9; Siz1; PCNA
A Phaseolus vulgaris EF-hand calcium-binding domain is induced early in the defense response against Colletotrichum lindemuthianum and by abiotic stress: Sequences shared between interacting partners
Keywords: Calcium signaling; EF-hand calcium-binding; SUMO; Light/dark co-regulation; Plant biotic and abiotic stress responses; UV-light response; Colletotrichum lindemuthianum-common bean pathosystems
ERM transcription factor contains an inhibitory domain which functions in sumoylation-dependent manner
Keywords: ETS; ERM; Transcription factor; SUMO; Regulation of transcription
Cell cycle-dependent kinetochore localization of condensin complex in Saccharomyces cerevisiae
Keywords: Cell cycle; Centromeres; Condensin; Kinetochores; SUMO
The rate of base excision repair of uracil is controlled by the initiating glycosylase
Keywords: BER; base excision repair; cccDNA; covalently closed circular DNA; dRP; deoxyribosephosphate; FEN1; flap endonuclease 1; Lig I; DNA ligase I; Lig III; DNA ligase III; LP; long patch; MBD4; methyl-binding domain 4; nAP; nicked abasic site; PARP; poly-(ADP-
Functional interaction of AIRE with PIAS1 in transcriptional regulation
Keywords: AIRE; PIAS; SUMO; Insulin promoter; Cystatin B (CSTB) promoter; SP100
Predicting the protein SUMO modification sites based on Properties Sequential Forward Selection (PSFS)
Keywords: Prediction; SUMO; SVM; AAindex; Sequential Forward Selection (SFS); Sumoylation
Effects of aging and dietary restriction on ubiquitination, sumoylation, and the proteasome in the spleen
Keywords: AL, ad libitum; DR, dietary restriction; NIA, National Institute of Aging; POMP, proteasome maturation protein; Sumo, small ubiquitin-like modifier; Ub, ubiquitinAging; POMP1; Proteasome; Spleen; Sumo; Ubiquitin
Production of sumoylated proteins using a baculovirus expression system
Keywords: Baculovirus; Wrn; Ubc9; SAE; SUMO; Sumoylation
Affinity chromatography of native SUMO proteins using His-tagged recombinant UBC9 bound to Co2+-charged talon resin
Keywords: SUMO; SUMO4; Affinity chromatography; MALDI-TOF; Ion exchange chromatography; Type 1 diabetes
N-terminal determinants of human cytomegalovirus IE1 protein in nuclear targeting and disrupting PML-associated subnuclear structures
Keywords: HCMV; IE1; PML; Nucleus; Localization; SUMO
A sensitive fluorescence intensity assay for deubiquitinating proteases using ubiquitin-rhodamine110-glycine as substrate
Keywords: Nedd8; Protease assay; Rhodamine; SUMO; Ubiquitin-specific proteases
A fluorescence-resonance-energy-transfer-based protease activity assay and its use to monitor paralog-specific small ubiquitin-like modifier processing
Keywords: SUMO; Ubiquitin-like modifier; Sentrin Protease; FRET; Paralog specificity; C-terminal hydrolase
Ligation independent cloning vectors for expression of SUMO fusions
Keywords: Ligation independent cloning; LIC; SUMO; Subtractive purification; Expressed protein ligation; EPL; Structural genomics
PIAS Proteins as Repressors of Oct4 Function
Keywords: SUMO, small ubiquitin-related modifier; PIAS, protein inhibitor of activated STAT; PGC, primordial germ cell; ES, embryonic stem; MT, Myc epitope; tk, thymidine kinase; TE, trophectoderm; ICM, inner cell massPIAS; POU; Oct4; SUMO; transcriptional repressi
SUMO on the road to neurodegeneration
Keywords: SUMO; Neurodegenerative diseases; Proteasome; Ubiquitin; Neuronal inclusions;