Keywords: LOC; lipid oligonucleotide conjugate; TLC; thin-layer chromatography; ACN; acetonitrile; TEAA; triethylammonium acetate; TOF; time-of-flight; ODN; oligodeoxyribonucleotide; CPG; controlled-pore glass; PBS; phosphate-buffered saline; DOPC; 1,2-dioleyl-l-α