Keywords: نقطه پایانی; Surrogate endpoint; Cancer; Overall survival; Meta-analysis; Randomized controlled trial; Systematic review;
مقالات ISI نقطه پایانی (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: نقطه پایانی; Left ventricular mass (LVM); LVM regression; cardiovascular mortality; chronic kidney disease (CKD); left ventricular hypertrophy; surrogate endpoint; surrogate outcome; cardioprotection; erythropoiesis-stimulating agent (ESA); renin-angiotensin-aldostero
Keywords: نقطه پایانی; Nasopharyngeal carcinoma; Surrogate endpoint; Chemotherapy; Radiotherapy; Failure-free survival; Progression-free survival;
Keywords: نقطه پایانی; Proteinuria; surrogate endpoint; kidney disease progression; disease trajectory; end-stage renal disease (ESRD); prognostic marker;
Early Change in Urine Protein as a Surrogate End Point in Studies of IgA Nephropathy: An Individual-Patient Meta-analysis
Keywords: نقطه پایانی; Proteinuria; urine protein; surrogate endpoint; IgA nephropathy (IgAN); end-stage renal disease (ESRD); prognostic marker; clinical end point; disease progression; kidney disease; glomerulonephritis; meta-analysis;
Promise and limits of the CellSearch platform for evaluating pharmacodynamics in circulating tumor cells
Keywords: نقطه پایانی; CTCs; Assay validation; Surrogate endpoint; Pharmacodynamics;
Change in Novel Filtration Markers and Risk of ESRD
Keywords: نقطه پایانی; β2-Microglobulin (B2M); creatinine; cystatin C; filtration marker; chronic kidney disease (CKD); disease progression; end-stage renal disease (ESRD); kidney disease outcome; surrogate endpoint;
Association of Drug Effects on Serum Parathyroid Hormone, Phosphorus, and Calcium Levels With Mortality in CKD: A Meta-analysis
Keywords: نقطه پایانی; Renal failure; surrogate endpoint; drug effect; biomarker; parathyroid hormone (PTH); phosphorus; calcium; outcomes; death; all-cause mortality; cardiovascular mortality; chronic kidney disease-mineral and bone disorder (CKD-MBD); phosphate binders; vit
The importance of biomarkers in neonatology
Keywords: نقطه پایانی; Acute-phase reactants; Biomarker; Metabolomics; Necrotizing enterocolitis; Neonatal sepsis; Sepsis biomarkers; Surrogate endpoint; Translational medicine
Patient blood management and outcome, too early or not?
Keywords: نقطه پایانی; patient blood management; outcome assessment; blood transfusion; surrogate endpoint; mortality; morbidity
Early Proctoscopy is a Surrogate Endpoint of Late Rectal Toxicity in Prostate Cancer Treated With Radiotherapy
Keywords: نقطه پایانی; Prostate cancer; Radiotherapy; Proctoscopy; Late toxicity; Rectal bleeding; Surrogate endpoint;
Issues surrounding clinical trial endpoints in solid malignancies with a focus on metastatic non-small cell lung cancer
Keywords: نقطه پایانی; Lung cancer; Progression-free survival; Overall survival; Surrogate endpoint; Disease control rate; Clinical research;
What is the clinical benefit of preoperative chemoradiotherapy with 5FU/leucovorin for T3-4 rectal cancer in a pooled analysis of EORTC 22921 and FFCD 9203 trials: Surrogacy in question?
Keywords: نقطه پایانی; Surrogate endpoint; Clinical trial; Rectal cancer; Neoadjuvant; Methodology; Local control;
Ultrasound and radiology surrogate endpoints in pharmacological studies
Keywords: نقطه پایانی; Surrogate endpoint; Carotid artery; Clinical trial; Flow-mediated dilatation; Ultrasound; Cardiac computed tomography; Magnetic resonance imaging;
Magnetic resonance biomarkers of neuroprotective effects in infants with hypoxic ischemic encephalopathy
Keywords: نقطه پایانی; Biological marker; Diffusion tensor imaging; Diffusion-weighted imaging; Magnetic resonance imaging; Magnetic resonance spectroscopy; Surrogate endpoint
Running a tightrope: Regulatory challenges in the development of antiretrovirals
Keywords: نقطه پایانی; HIV-1; Drug regulations; Accelerated approval; Surrogate endpoint; Fast track; Clinical trial designs; Resistance; PEPFAR; Expanded access
Simplified modeling strategies for surrogate validation with multivariate failure-time data
Keywords: نقطه پایانی; Frailty model; Meta-analytic approach; Failure-time data; Random effects; Surrogate endpoint
Does the decision in a validation process of a surrogate endpoint change with level of significance of treatment effect? A proposal on validation of surrogate endpoints
Keywords: نقطه پایانی; Surrogate endpoint; Validation criteria; Colon cancer; Meta-analytic; Clinical trials;
Surrogate markers in clinical trials—Challenges and opportunities
Keywords: نقطه پایانی; Surrogate endpoint; Atherosclerosis; Cardiovascular disease; Plasma biomarker; Vascular imaging
Validation of novel imaging methodologies for use as cancer clinical trial end-points
Keywords: نقطه پایانی; Surrogate endpoint; Phase II clinical trial; Meta-analysis; Imaging endpoint; RECIST
Análisis cuantitativo de la función ventricular izquierda como herramienta para la investigación clÃnica. Fundamentos y metodologÃa
Keywords: نقطه پایانی; Función ventricular izquierda; Fracción de eyección ventricular izquierda; Objetivo subrogado; Corelab; Left ventricular function; Left ventricular ejection fraction; Surrogate endpoint; Core lab; FEVI; fracción de eyección del ventrÃculo izquierdo;
The meta-analytic framework for the evaluation of surrogate endpoints in clinical trials
Keywords: نقطه پایانی; Hierarchical model; Likelihood reduction factor; Meta-analysis; Random-effects model; Surrogate endpoint; Surrogate threshold effect
How Useful Is Root Canal Culturing in Predicting Treatment Outcome?
Keywords: نقطه پایانی; Evidence-based; microbiology; performance; surrogate endpoint;
Change in MRI striatal volumes as a biomarker in preclinical Huntington's disease
Keywords: نقطه پایانی; Clinical trial; Huntington's disease; Preclinical; Biomarker; Surrogate endpoint
Flexible surrogate marker evaluation from several randomized clinical trials with continuous endpoints, using R and SAS
Keywords: نقطه پایانی; Adjusted association; Hierarchical model; Meta-analysis; Proportion explained; Random-effects model; Relative effect; Surrogate endpoint
Prostate-specific antigen (PSA) alone is not an appropriate surrogate marker of long-term therapeutic benefit in prostate cancer trials
Keywords: نقطه پایانی; PSA; Surrogate endpoint; Clinical trials; Prostate cancer; Prognostic factor
Posttreatment prostatic-specific antigen doubling time as a surrogate endpoint for prostate cancer-specific survival: An analysis of Radiation Therapy Oncology Group Protocol 92-02
Keywords: نقطه پایانی; Prostate cancer; Prostate-specific antigen doubling time; Mortality; Surrogate endpoint;
Robust analysis of biomarker data with informative missingness using a two-stage hypothesis test in an HIV treatment interruption trial: AIEDRP AIN503/ACTG A5217
Keywords: نقطه پایانی; Surrogate endpoint; HIV treatment interruption trial; Missing data; Bias; Robust analysis
New science-based endpoints to accelerate oncology drug development
Keywords: نقطه پایانی; Drug development; Oncology; Surrogate endpoint; Biomarker; Genomics; Proteomics; Functional imaging; Molecular imaging;