Keywords: RLK; receptor-like kinase; RTK; receptor tyrosine kinase; IRAK; interleukin-1 receptor-associated kinase; SYMRK; Symbiosis Receptor Kinase; WT; wild-type; Trx; thioredoxin; CD; circular dichroism; Gatekeeper tyrosine; Autophosphorylation; Autoinhibition;