Keywords: Mechanotransduction; Syndecan-4; Dorsal root ganglion; Protein kinase C; Focal adhesion kinase; Polydimethylsiloxane;
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Effects of heparan sulfate proteoglycan syndecan-4 on the insulin secretory response in a mouse pancreatic β-cell line, MIN6
Keywords: Core protein; Heparan sulfate; Insulin secretory response; Proteoglycan; Syndecan-4;
Syndecan-4 deficiency accelerates the transition from compensated hypertrophy to heart failure following pressure overload
Keywords: Syndecan-4; Angiogenesis; Cardiac hypertrophy; Heart failure; PKCα;
Syndecan-4, a PRRSV attachment factor, mediates PRRSV entry through its interaction with EGFR
Keywords: Porcine reproductive and respiratory syndrome virus; Attachment; Entry; Syndecan-4; EGFR
Full length articleSyndecan-4 enhances PDGF-BB activity in diabetic wound healing
Keywords: Syndecan-4; Wound healing; Diabetes; Platelet derived growth factor-BB (PDGF-BB); Growth factor therapy;
Syndecan-4 shedding impairs macrovascular angiogenesis in diabetes mellitus
Keywords: Syndecan-4; Diabetes mellitus; Shedding;
Crystal structure of syndesmos and its interaction with Syndecan-4 proteoglycan
Keywords: Syndesmos; Nudix hydrolase; Syndecan-4; X-ray crystallography; NMR spectroscopy;
MMPs and ADAMTSs in intervertebral disc degeneration
Keywords: IVD; intervertebral disc; IDD; intervertebral disc degeneration; ECM; extracellular matrix; MMPs; matrix metalloproteinases; ADAMTSs; a disintegrin and metalloprotease with thrombospondin motifs; NP; nucleus pulposus; AF; annulus fibrosus; Col I; type I c
Targeting glycosaminoglycans in the lung by an engineered CXCL8 as a novel therapeutic approach to lung inflammation
Keywords: BAL; brochoalveolar lavage; COPD; chronic obstructive pulmonary disease; CF; cystic fibrosis; GAG; glycosaminoglycan; GM-CSF; granulocyte macrophage colony-stimulating factor; HMVEC-L; human lung microvascular endothelial cells; KC; keratinocytes-derived
Syndecan-4 ectodomain evokes mobilization of podocyte TRPC6 channels and their associated pathways: An essential role for integrin signaling
Keywords: ADAM17; A disintegrin and metalloproteinase 17; Ang II; angiotensin II; CGT; cilengitide; CsA; cyclosporine A; DAG; diacylglycerol; FSGS; focal and segmental glomerulosclerosis; GBM; glomerular basement membrane; NFATc1; nuclear factor of activated T-cell
Molecular interplays involved in the cellular uptake of octaarginine on cell surfaces and the importance of syndecan-4 cytoplasmic V domain for the activation of protein kinase Cα
Keywords: CPPs; cell-penetrating peptides; GAGs; glycosaminoglycans; HSPGs; heparan sulfate proteoglycans; Syn-4; syndecan-4; CD; cytoplasmic domain; PKCα; protein kinase C-alpha; PtdIns[4,5]P2; phosphatidylinositol (4,5) bisphosphate; Syn-4ÎV; V domain-lacking s
High glucose modifies transient receptor potential canonical type 6 channels via increased oxidative stress and syndecan-4 in human podocytes
Keywords: Diabetic nephropathy; Podocytes; Transient receptor potential channels; Syndecan-4; High glucose; Oxidative stress;
Up-regulation of TGM2 with ITGB1 and SDC4 is important in the development and metastasis of renal cell carcinoma
Keywords: Tissue transglutaminase; Renal cell carcinoma; Integrin β1; Syndecan-4; Metastasis;
Syndecan-4 inhibits Wnt/β-catenin signaling through regulation of low-density-lipoprotein receptor-related protein (LRP6) and R-spondin 3
Keywords: Wnt; Syndecan-4; LRP6; Fibronectin; R-spondin;
EGFR and HER2 exert distinct roles on colon cancer cell functional properties and expression of matrix macromolecules
Keywords: EGFR; epidermal growth factor receptor; HER2; human epidermal receptor 2; ECM; extracellular matrix; MMPs; matrix metalloproteinases; MT-MMPs; membrane type-matrix metalloproteinases; TIMPs; tissue inhibitor of matrix metaloproteinases; uPA; plasminogen a
Thy-1-mediated cell-cell contact induces astrocyte migration through the engagement of αVβ3 integrin and syndecan-4
Keywords: Thy-1; Integrin; Syndecan-4; Neuron-astrocyte interaction; Cell migration;
Syndecan-4 signaling via NFAT regulates extracellular matrix production and cardiac myofibroblast differentiation in response to mechanical stress
Keywords: Mechanical stress; Cardiac fibroblast; Extracellular matrix; Myofibroblast; Syndecan-4; NFAT
Syndecan-4 and fibronectin in osteosarcoma
Keywords: Fibronectin; immunohistochemistry; osteosarcoma; syndecan-4;
Probing the interaction between heparan sulfate proteoglycan with biologically relevant molecules in mimetic models for cell membranes: A Langmuir film study
Keywords: PM-IRRAS; polarization-modulation infrared reflection-absorption spectroscopy; HSPGs; heparan sulfate proteoglycans; EGF; epidermal growth factor; EC; endothelial cell; EJ-ras EC; Endothelial cell transfected with EJ-ras oncogene; shRNA-Syn4-EC; EC tr
Host cell/Orientia tsutsugamushi interactions: Evolution and expression of syndecan-4 in Asian rodents (Rodentia, Muridae)
Keywords: Zoonotic disease; Scrub typhus; Orientia tsutsugamushi; Syndecan-4; Rattini; Murini;
Osteoarthritis year 2010 in review: pathomechanisms
Keywords: Cartilage destruction; Metalloproteinases; Chondrocytes; Autophagy; OA cartilage pathology; TGFβ; S100A8; HIF-2α; Syndecan-4; DDR-2
Recombinant expression, purification, and characterization of transmembrane domain of syndecan-4
Keywords: Syndecan-4; Transmembrane protein; Expression; Purification; NMR;
CXCR7 and syndecan-4 are potential receptors for CXCL12 in human cytotrophoblasts
Keywords: CXCL12; CXCR7; Syndecan-4; Placenta; Cytotrophoblast;
Muscle satellite cells from GRMD dystrophic dogs are not phenotypically distinguishable from wild type satellite cells in ex vivo culture
Keywords: Syndecan-4; Satellite cells; GRMD; Muscular dystrophy;
Fibroblast growth factor-2 modulates melanoma adhesion and migration through a syndecan-4-dependent mechanism
Keywords: FGF-2; Syndecan-4; Melanoma; Adhesion; Migration
Syndecan-4 regulates platelet-derived growth factor-mediated MAP kinase activation by altering intracellular reactive oxygen species
Keywords: Reactive oxygen species; Syndecan-4; MAP kinase; Platelet-derived growth factor; DCF; fluorescent 2â²,7â²-dichlorofluorescein; ECM; extracellular matrix; FBS; fetal bovine serum; GST; glutathione-S-transferase; PDGF; platelet-derived growth factor; REF;
The oligomeric status of syndecan-4 regulates syndecan-4 interaction with α-actinin
Keywords: Syndecan-4; Oligomerization; α-Actinin; Cytoskeletal organization; Focal adhesion
Protein kinase Cα can undergo membrane localization via an alternative phosphatidylinositol 4,5-bisphosphate-dependent pathway
Keywords: Phosphatidylinositol 4,5-bisphosphate; Protein kinase C; Syndecan-4; Membrane localization; Cytoskeleton
Syndecan-4 dependent FGF stimulation of mouse vibrissae growth
Keywords: FGF signaling; Syndecan-4; Growth; Regeneration; Mouse vibrissae
EJ-ras oncogene transfection of endothelial cells upregulates the expression of syndecan-4 and downregulates heparan sulfate sulfotransferases and epimerase
Keywords: EJ-ras oncogene; Sulfotransferases; Phorbol ester; Syndecan-4; Heparan sulfate structure; BrdU; 5-bromo-2â²-deoxyuridine; ÎGlcA-GlcNAc,6S or ÎIdoA-GlcNAc,6S; O-(4-deoxy-hex-4-enopyranosyluronic acid)-(1â4)-2-acetamido-d-glucose 6-sulfate; ÎGlcA-GlcN
Structural Basis of Syndecan-4 Phosphorylation as a Molecular Switch to Regulate Signaling
Keywords: NMR; solution structure; syndecan-4; phosphorylation; phosphatidylinositol 4, 5-bisphosphateHSPG, heparan sulfate proteoglycan; V, variable; C, constant; PtdIns(4,5)P2, phosphatidylinositol 4,5-bisphosphate; PKC, protein kinase C; NOESY, nuclear Overhause
Src tyrosine kinase-dependent migratory effects of antithrombin in leukocytes
Keywords: Leukocytes; Syndecan-4; Antithrombin; Src tyrosine kinase; Migration;
Reduced syndecan-4 expression in arterial smooth muscle cells with enhanced proliferation
Keywords: Syndecan-4; Heparan sulfate; Proteoglycans; Smooth muscle cells; Atherosclerosis; Cell proliferation;
Three-Dimensional Migration of Human Adult Dermal Fibroblasts from Collagen Lattices into Fibrin/Fibronectin Gels Requires Syndecan-4 Proteoglycan
Keywords: cell migration; fibroblast; fibronectin; heparan sulfate; syndecan-4; wounds;