Investigation of solubilising effects of bile salts on an active pharmaceutical ingredient with unusual pH dependent solubility by NMR spectroscopy
Keywords: DOSY, Diffusion Ordered Spectroscopy; TC, taurocholate; L, lecithin; NOE, Nuclear Overhauser Effect/Enhancement; FaSSIF, Fasted State Simulated Intestinal FluidBiophysical models; Diffusion; Dissolution; Gastrointestinal; Micelles; NMR; Taurocholate–lecit