
Persistent activation of DNA damage signaling in response to complex mixtures of PAHs in air particulate matter
Keywords: PAH, polycyclic aromatic hydrocarbon; PM, particulate matter; BP, benzo[a]pyrene; DBP, dibenzo[a,l]pyrene; Chk1, checkpoint kinase 1; CYP, cytochrome P450; TEF, toxic equivalency factor; RPF, relative potency factor; SPE, solid phase extraction; DDR, DNA