دانلود مقالات ISI درباره Th-T + ترجمه فارسی

اکسیداسیون تک سلولی پس از ترجمه به اندازه کافی برای به خطر انداختن ثبات جنبشی پروتئین های کروی و ترویج آمیلوئید

A single cysteine post-translational oxidation suffices to compromise globular proteins kinetic stability and promote amyloid formation

Keywords: PTM; post-translational modifications; ROS; reactive oxygen species; MSO; methionine sulfoxide; CD; circular dichroism; MD; molecular dynamics; Th-T; thioflavin T; CR; Congo red; Protein oxidation; Protein misfolding; Protein aggregation; Oxidative stress

دانلود رایگان متن کامل مقاله ISI 29 صفحه سال انتشار : 2018 سفارش ترجمه

یک روش سریع و خاص برای نمایش برای مهار کننده های آمیلیید داخل سلولی با استفاده از سیستم های مدل باکتری

A fast and specific method to screen for intracellular amyloid inhibitors using bacterial model systems

Keywords: Amyloid; Protein aggregation inhibitors; Inclusion bodies; ProteoStat; Screening; Aβ; β-amyloid peptide; AD; Alzheimer's disease; APF; aggregation propensity factor; APP; amyloid precursor protein; CR; Congo Red; DMSO; dimethyl sulfoxide; FC; flow cytom

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2016 سفارش ترجمه

Mechanistic analyses of the suppression of amyloid β42 aggregation by apomorphine

Keywords: Aβ; amyloid β-protein; AD; Alzheimer's disease; HFIP; 1,1,1,3,3,3,-hexafluoroisopropyl alcohol; HMQC; heteronuclear multiple quantum coherence; HPLC; high performance liquid chromatography; LC-MS; liquid chromatography-mass spectrometry; LC/Q Tof-MS

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2018 سفارش ترجمه

Inhibition of Alzheimer's amyloid-beta aggregation in-vitro by carbenoxolone: Insight into mechanism of action

Keywords: Alzheimer's disease; Amyloid-beta 42; Carbenoxolone; Oligomers; Fibrils; Anti-fibrillation; AD; Alzheimer's disease; Aβ; Amyloid beta; Cbx; carbenoxolone; APP; Amyloid precursor protein; Th-T; Thioflavin-T; CD; Circular dichroism; SVAU; Sedimentation vel

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2017 سفارش ترجمه

Overcoming electrostatic repulsions during amyloid assembly: Effect of pH and interaction with divalent metals using model peptides

Keywords: Amyloid; Peptides; Electrostatic repulsion; pH; Divalent metals; Coordination; Th-T; Thioflavin-T; Mg+2; magnesium ion; Mn+2; manganese ion; K+; potassium ion; TEM; transmission electron microscopy; NTases; nucleotydil transferases;

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2017 سفارش ترجمه

Inhibition of amyloid fibril formation and cytotoxicity by caffeic acid-conjugated amyloid-β C-terminal peptides

Keywords: Aβ; amyloid-β; AD; Alzheimer's disease; CA; caffeic acid; DCFH-DA; 2′,7′-dichlorodihydrofluorescein diacetate; DHCA; dihydrocaffeic acid; DIPEA; N,N-diisopropylethylamine; DMF; N,N-dimethylformamide; DMSO; dimethyl sulfoxide; Gly; glycine; HBTU; O

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2016 سفارش ترجمه

Ginsenoside Rb1 inhibits fibrillation and toxicity of alpha-synuclein and disaggregates preformed fibrils

Keywords: α-syn; α-synuclein; PD; Parkinson's disease; Aβ; beta amyloid; LBs; Lewy bodies; LNs; Lewy neuritis; Gn; ginsenoside; GST; glutathione S-transferase; IPTG; isopropyl β-d-1-thiogalactopyranoside; DTT; dithiothreitol; SDS; sodium dodecyl sulfate; PBS; p

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Toward a common aggregation mechanism for a β-barrel protein family: Insights derived from a stable dimeric species

Keywords: IFABP; intestinal fatty acid binding protein; Δ98Δ; a truncated variant of IFABP corresponding to the fragment 29-126 of the parent protein; Δ78Δ; a truncated variant of IFABP corresponding to the fragment 29-106 of the parent protein; TFE; 2,2,2-

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Active and peripheral anionic sites of acetylcholinesterase have differential modulation effects on cell proliferation, adhesion and neuritogenesis in the NG108-15 cell line

Keywords: Acetylcholinesterase; Peripheral anionic site; Acylation site; Cell adhesion; Proliferation; Neuritogenesis; ACh; acetylcholine; AChE; acetylcholinesterase; BSA; bovine serum albumin; ChE; cholinesterase; CV; crystal violet; dbcAMP; (dybutyryl cyclic-AMP)

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Gadolinium-based contrast agents targeted to amyloid aggregates for the early diagnosis of Alzheimer's disease by MRI

Keywords: Alzheimer's disease; Amyloid; Gadolinium; DOTA; Pyridine containing TriAza (PCTA); Magnetic resonance imaging (MRI); BAT; bis-amine-bis-thiol; BTA; 2-(4-N-methylaminophenyl)benzothiazole; CA; contrast agent; CMC; critic micelle concentration; CV; cone vol

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2014 سفارش ترجمه

Non-toxic conformer of amyloid β may suppress amyloid β-induced toxicity in rat primary neurons: Implications for a novel therapeutic strategy for Alzheimer's disease

Keywords: AD; Alzheimer's disease; Aβ40; 40-mer amyloid β-protein; Aβ42; 42-mer amyloid β-protein; DIV; days in vitro; IgG; immunoglobulin G; iPSCs; induced pluripotent stem cells; MTT; 3-(4,5-di-methylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; NMR; nucle

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه