In search of diamine analogs of the α,α-diphenyl prolinol privileged chiral organocatalyst. Synthesis of diamine derivatives of α,α-diphenyl-(S)-prolinol and their application as organocatalysts in the asymmetric Michael and Mannich reactions
Keywords: Organocatalysis; Proline derivatives; Thorpe-Ingold effect; Asymmetric Michael addition; Asymmetric Mannich reaction; Water effect;