
RNase domains determine the functional difference between IRE1α and IRE1β
Keywords: aa, amino acid; ER, endoplasmic reticulum; hIRE1, human IRE1; rIRE1, recombinant hIRE1 protein; RNase, endoribonuclease; Tm, tunicamycin; UPR, unfolded protein responseER stress; IRE1; Unfolded protein response