Divergent signature motifs of nucleotide binding domains of ABC multidrug transporter, CaCdr1p of pathogenic Candida albicans, are functionally asymmetric and noninterchangeable
Keywords: ABC, ATP binding cassette; PDR, pleiotropic drug resistance; NBD, nucleotide binding domain; TMD, transmembrane domain; TMS, transmembrane segment; PM, plasma membrane; FLC, fluconazole; CYH, cycloheximide; ANI, anisomycin; R6G, rhodamine 6G; [125I] IAAP,