
Endothelial microsomal prostaglandin E synthase-1 facilitates neurotoxicity by elevating astrocytic Ca2+ levels
Keywords: PGE2, prostaglandin E2; COX, cyclooxygenase; PGES, PGE2-synthesizing enzyme; mPGES-1, microsomal prostaglandin E synthase-1; KA, kainic acid; TMT, trimethyltin; [Ca2+]i, intracellular Ca2+; WT, wild-type; mPGES-1−/−, mPGES-1 knockout mice; GFAP, glial fib